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Centre intégré universitaire de santé
et de services sociaux de l'Est-de-l'Île-de-Montréal

Centre intégré universitaire de santé et de services sociaux de l'Est-de-l'Île-de-Montréal

Denis-Claude Roy, M.D.

Denis-Claude Roy

Hématologue-greffeur, Professeur titulaire

L'équipe de l’IHOT

Chercheur-clinicien

Contact

Tél. : 514 252-3400, poste 5503

Précurseur dans le domaine de la thérapie cellulaire, Dr Denis Claude Roy a pour principaux champs d’intérêt la greffe hématopoïétique autologue et allogénique, la maladie du greffon contre l’hôte (GVHD) ainsi que la thérapie cellulaire, incluant les cellules souches en médecine régénératrice oculaire et cardiaque.

 

  • Membre fondateur et directeur de l'Institut universitaire d'hématologie-oncologie et de thérapie cellulaire (IHOT)
  • Directeur du CETC (Centre d’excellence en thérapie cellulaire) HMR
  • Directeur de l'unité de recherche en Thérapie cellulaire du Centre de recherche HMR
  • Membre fondateur et directeur scientifique Centre C3i (commercialisation de l’immunothérapie du cancer)
  • Membre fondateur et directeur général, CellCAN (Réseau canadien de médecine régénératrice et de thérapie cellulaire)
  • Entrée en poste à l’Hôpital Maisonneuve-Rosemont : 1990

 

Formation :

  • Fellowship en immunologie tumorale : Dana-Farber Cancer Institute de l'Université Harvard, Boston (États-Unis), 1987-1990
  • Résidences en médecine interne et hématologie : Université de Montréal (Canada), 1983-1987
  • Doctorat en médecine : Université de Montréal (Canada), 1977-1982

 

Découvrez ses publications

  • Improved outcomes of UM171-expanded cord blood transplantation compared with other graft sources: real-world evidence

    Sandra Cohen , Nadia Bambace , Imran Ahmad , Jean Roy , Xiaoying Tang, Mei-Jie Zhang, Linda Burns, Frédéric Barabé , Léa Bernard , Jean-Sébastien Delisle , Thomas Kiss , Sylvie Lachance , Denis-Claude Roy , Olivier Veilleux , Guy Sauvageau
    DOI 10.1182/bloodadvances.2023010599 PMID 37467030
    Consulter

  • Impact of Implementing a Bendamustine-Based Conditioning Regimen on Outcomes of Autologous Stem Cell Transplantation in Lymphoma while Novel Cellular Therapies Emerge

    Sylvie Lachance , Alex Bourguignon, Josie-Anne Boisjoly, Philippe Bouchard , Imran Ahmad , Nadia Bambace , Léa Bernard , Sandra Cohen , Jean-Sébastien Delisle , Isabelle Fleury , Thomas Kiss , Luigina Mollica , Denis-Claude Roy , Guy Sauvageau , Olivier Veilleux , Justine Zehr, Miguel Chagnon , Jean Roy
    DOI 10.1016/j.jtct.2022.10.003 PMID 36243319
    Consulter

  • Bortezomib Maintenance After Allogeneic Transplantation in Newly Diagnosed Myeloma Patients Results in Decreased Incidence and Severity of Chronic GVHD

    Jean-Sébastien Claveau , Richard LeBlanc , Imran Ahmad , Jean-Sébastien Delisle , Sandra Cohen , Thomas Kiss , Nadia Bambace , Léa Bernard , Sylvie Lachance , Denis-Claude Roy , Guy Sauvageau , Olivier Veilleux , Jean Roy
    DOI 10.1016/j.jtct.2022.10.022 PMID 36334654
    Consulter

  • Donor Age and Non-Relapse Mortality: Study of Their Association after HLA-Matched Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndrome

    Yasmine Kadri, Michelle Phan, Nadia Bambace , Léa Bernard , Sandra Cohen , Jean-Sébastien Delisle , Thomas Kiss , Sylvie Lachance , Denis-Claude Roy , Guy Sauvageau , Olivier Veilleux , Jean Roy , Imran Ahmad
    DOI 10.3390/curroncol29080470 PMID 36005208
    Consulter

  • Two types of human TCR differentially regulate reactivity to self and non-self antigens

    Assya Trofimov, Philippe Brouillard, Jean-David Larouche, Jonathan Séguin, Jean-Philippe Laverdure, Ann Brasey, Gregory Ehx , Denis-Claude Roy , Lambert Busque , Sylvie Lachance , Sébastien Lemieux, Claude Perreault
    DOI 10.1016/j.isci.2022.104968 PMID 36111255
    Consulter

  • Negative Regulation of Zap70 by Lck Forms the Mechanistic Basis of Differential Expression in CD4 and CD8 T Cells

    Hassan Damen, Christian Tebid, Melissa Viens , Denis-Claude Roy , Vibhuti P Dave
    DOI 10.3389/fimmu.2022.935367 PMID 35860252
    Consulter

  • Real-World Outcomes of Autologous and Allogeneic Hematopoietic Stem Cell Transplantation for Relapsed/Refractory Hodgkin Lymphoma in the Era of Novel Therapies: A Canadian Perspective

    Olivier Veilleux , Jean-Sébastien Claveau , Habiba Alaoui , Jean Roy , Imran Ahmad , Jean-Sébastien Delisle , Thomas Kiss , Nadia M Bambace , Léa Bernard , Sandra Cohen , Guy Sauvageau , Isabelle Fleury , Luigina Mollica , Denis-Claude Roy , Yasmina Serroukh , Sylvie Lachance
    DOI 10.1016/j.jtct.2021.12.005 PMID 34954149
    Consulter

  • Outcomes in newly diagnosed young or high-risk myeloma patients receiving tandem autologous/allogeneic transplant followed by bortezomib maintenance: a phase II study

    Richard LeBlanc , Imran Ahmad , Rafik Terra, Jean-Samuel Boudreault, David Ogez, Kristopher Lamore , Jean-Sébastien Delisle , Nadia Bambace , Léa Bernard , Sandra Cohen , Thomas Kiss , Sylvie Lachance , Séverine Landais, Émilie Lemieux-Blanchard , Guy Sauvageau , Michael Sebag , Denis-Claude Roy , Jean Roy
    DOI 10.1038/s41409-021-01532-2 PMID 34845367
    Consulter

  • UM171-Expanded Cord Blood Transplants Support Robust T Cell Reconstitution with Low Rates of Severe Infections

    Maude Dumont-Lagacé, Qi Li , Mégane Tanguay , Jalila Chagraoui, Tibila Kientega, Guillaume B Cardin, Ann Brasey, Assya Trofimov, Cédric Carli , Imran Ahmad , Nadia M Bambace , Léa Bernard , Thomas Kiss , Jean Roy , Denis-Claude Roy , Sébastien Lemieux, Claude Perreault, Francis Rodier, Simon Frédéric Dufresne , Lambert Busque , Sylvie Lachance , Guy Sauvageau , Sandra Cohen , Jean-Sébastien Delisle
    DOI 10.1016/j.bbmt.2020.09.031 PMID 33022376
    Consulter

  • Single UM171-expanded cord blood transplant can cure severe idiopathic aplastic anemia in absence of suitable donors

    Jean-Sébastien Claveau , Sandra Cohen , Imran Ahmad , Jean-Sébastien Delisle , Thomas Kiss , Sylvie Lachance , Guy Sauvageau , Lambert Busque , Rose-Marie Brito, Nadia Bambace , Léa Bernard , Denis-Claude Roy , Jean Roy
    DOI 10.1111/ejh.13504 PMID 32749758
    Consulter

  • Newly diagnosed multiple myeloma patients treated with tandem auto-allogeneic stem cell transplant have better overall survival with similar outcomes at time of relapse compared to patients who received autologous transplant only

    Richard LeBlanc , Jean-Sébastien Claveau , Imran Ahmad , Jean-Sébastien Delisle , Nadia M Bambace , Léa Bernard , Sandra Cohen , Thomas Kiss , Sylvie Lachance , Séverine Landais , Denis-Claude Roy , Guy Sauvageau , Jean Roy
    DOI 10.1111/ctr.14099 PMID 32981146
    Consulter

  • Stigma associated with parental depression or cancer: Impact on spouse and offspring's cortisol levels and socioemotional functioning

    Sonia J Lupien , Denis-Claude Roy , Catherine Raymond, Sarah Leclaire, Nathalie Wan, Réal Labelle, Charles-Édouard Giguère, Isabelle Ouellet-Morin
    DOI 10.1017/S0954579420001431 PMID 33427165
    Consulter

  • Analysis of the COMPARE-AMI trial: First report of long-term safety of CD133+ cells

    Kevin Haddad, Brian James Potter, Alexis Matteau, François Reeves, Guy Leclerc, Alain Rivard, François Gobeil , Denis-Claude Roy , Nicolas Noiseux, Samer Mansour
    DOI 10.1016/j.ijcard.2020.06.004 PMID 32553596
    Consulter

  • Closing the system: production of viral antigen-presenting dendritic cells eliciting specific CD8+ T cell activation in fluorinated ethylene propylene cell culture bags

    Jean-Philippe Bastien, Natalie Fekete, Ariane V Beland, Marie-Paule Lachambre, Veronique Laforte, David Juncker, Vibhuti Dave , Denis-Claude Roy , Corinne A Hoesli
    DOI 10.1186/s12967-020-02543-1 PMID 33036618
    Consulter

  • ATIR101 administered after T-cell-depleted haploidentical HSCT reduces NRM and improves overall survival in acute leukemia

    Denis-Claude Roy , Irwin Walker, Johan Maertens, Philippe Lewalle, Eduardo Olavarria, Dominik Selleslag , Sylvie Lachance , Marc Buyse, Kun Wang, Jeroen Rovers, Irene Santi, Halvard Bonig, Andrew Sandler, Jurjen Velthuis, Stephan Mielke
    DOI 10.1038/s41375-020-0733-0 PMID 32047237
    Consulter

  • Persistence of Drug-Resistant Leukemic Stem Cells and Impaired NK Cell Immunity in CML Patients Depend on MIR300 Antiproliferative and PP2A-Activating Functions

    Giovannino Silvestri; Rossana Trotta; Lorenzo Stramucci; Justin J. Ellis; Jason G. Harb; Paolo Neviani; Shuzhen Wang , Ann-Kathrin Eisfeld; Christopher J. Walker; Bin Zhang; Klara Srutova; Carlo Gambacorti-Passerini; Gabriel Pineda; Catriona H. M. Jamieson; Fabio Stagno; Paolo Vigneri; Georgios Nteliopoulos; Philippa C. May; Alistair G. Reid; Ramiro Garzon , Denis-Claude Roy , Moutuaata M. Moutuou; Martin Guimond; Peter Hokland; Michael W. Deininger; Garrett Fitzgerald; Christopher Harman; Francesco Dazzi; Dragana Milojkovic; Jane F. Apperley; Guido Marcucci; Jianfei Qi , Katerina Machova Polakova; Ying Zou; Xiaoxuan Fan; Maria R. Baer; Bruno Calabretta; Danilo Perrotti
    DOI 10.1158/0008-5472.BCD-19-0039 PMID 32974613
    Consulter

  • Hematopoietic stem cell transplantation using single UM171-expanded cord blood: a single-arm, phase 1-2 safety and feasibility study

    Sandra Cohen , Jean Roy , Sylvie Lachance , Jean-Sébastien Delisle , Anne Marinier , Lambert Busque , Denis-Claude Roy , Imran Ahmad , Nadia M Bambace , Léa Bernard , Thomas Kiss , Philippe Bouchard, Pierre Caudrelier, Sévérine Landais, Fannie Larochelle, Jalila Chagraoui, Bernhard Lehnertz, Sophie Corneau, Elisa Tomellini, Jeroen J A van Kampen, Jan J Cornelissen, Maude Dumont-Lagacé, Mégane Tanguay, Qi Li , Sébastien Lemieux, Peter W Zandstra , Guy Sauvageau
    DOI 10.1016/S2352-3026(19)30202-9 PMID 31704264
    Consulter

  • Evaluation of the Impact of Autologous Hematopoietic Stem Cell Transplantation on the Quality of Life of Older Patients with Lymphoma

    Christopher Lemieux , Imran Ahmad , Nadia M. Bambace , Léa Bernard , Sandra Cohen , Jean-Sébastien Delisle , Isabelle Fleury , Thomas Kiss , Luigina Mollica , Denis-Claude Roy , Guy Sauvageau , Jean Roy , Sylvie Lachance
    DOI 10.1016/j.bbmt.2019.09.007 PMID 31521818
    Consulter

  • Clinical applications of donor lymphocyte infusion from an HLA-haploidentical donor: consensus recommendations from the Acute Leukemia Working Party of the EBMT

    Bhagirathbhai Dholaria, Bipin N Savani, Myriam Labopin, Leo Luznik, Annalisa Ruggeri, Stephan Mielke, Monzr M Al Malki, Piyanuch Kongtim, Ephraim Fuchs, Xiao-Jun Huang , Franco Locatelli, Franco Aversa, Luca Castagna, Andrea Bacigalupo, Massimo Martelli, Didier Blaise, Patrick Ben Soussan, Yolande Arnault, Rupert Handgretinger , Denis-Claude Roy , Paul O'Donnell, Asad Bashey, Scott Solomon, Rizwan Romee, Philippe Lewalle, Jorge Gayoso, Michael Maschan, Hillard M Lazarus, Karen Ballen , Sebastian Giebel, Frederic Baron, Fabio Ciceri, Jordi Esteve, Norbert-Claude Gorin, Alexandros Spyridonidis, Christoph Schmid, Stefan O Ciurea, Arnon Nagler, Mohamad Mohty
    DOI 10.3324/haematol.2019.219790 PMID 31537691
    Consulter

  • The European Society for Blood and Marrow Transplantation (EBMT) consensus recommendations for donor selection in haploidentical hematopoietic cell transplantation

    Stefan O. Ciurea, Monzr M. Al Malki, Piyanuch Kongtim, Ephraim J. Fuchs, Leo Luznik, Xiao-Jun Huang, Fabio Ciceri, Franco Locatelli, Franco Aversa, Luca Castagna, Andrea Bacigalupo, Massimo Martelli , Didier Blaise, Patrick Ben Soussan, Yolande Arnault, Rupert Handgretinger , Denis-Claude Roy , Paul V. O’Donnell, Asad Bashey, Scott Solomon, Rizwan Romee, Jorge Gayoso, Hillard M. Lazarus, Karen Ballen, Bipin N. Savani, Mohamad Mohty, Arnon Nagler
    DOI 10.1038/s41409-019-0499-z PMID 30833742
    Consulter

  • Allodepleted T-cell immunotherapy after haploidentical haematopoietic stem cell transplantation without severe acute graft-versus-host disease (GVHD) in the absence of GVHD prophylaxis

    Denis-Claude Roy , Sylvie Lachance , Sandra Cohen , Jean-Sébastien Delisle , Thomas Kiss , Guy Sauvageau , Lambert Busque , Imran Ahmad , Léa Bernard , Nadia M Bambace, Radia S Boumédine, Marie-Claude Guertin, Katayoun Rezvani, Stephan Mielke, Claude Perreault , Jean Roy
    DOI 10.1111/bjh.15970 PMID 31135970
    Consulter

  • Critical Role for TCR Signal Strength and MHC Specificity in ThPOK-Induced CD4 Helper Lineage Choice

    Nabil Zeidan, Hassan Damen , Denis-Claude Roy , Vibhuti P Dave
    DOI 10.4049/jimmunol.1801464 PMID 31036767
    Consulter

  • Correction: The European Society for Blood and Marrow Transplantation (EBMT) Consensus Guidelines for the Detection and Treatment of Donor-specific Anti-HLA Antibodies (DSA) in Haploidentical Hematopoietic Cell Transplantation

    Stefan O Ciurea, Kai Cao, Marcelo Fernandez-Vina, Piyanuch Kongtim, Monzr Al Malki, Ephraim Fuchs, Leo Luznik, Xiao-Jun Huang, Fabio Ciceri, Franco Locatelli , Franco Aversa, Luca Castagna, Andrea Bacigalupo, Massimo Martelli, Didier Blaise, Rupert Handgretinger , Denis-Claude Roy , Paul O'Donnell, Asad Bashey, Hillard M Lazarus, Karen Ballen, Bipin N Savani, Mohamad Mohty, Arnon Nagler
    DOI 10.1038/s41409-018-0332-0 PMID 30232413
    Consulter

  • Outcome of autologous hematopoietic stem cell transplant in older patients with B cell lymphoma when selected for fitness and chemosensitive disease

    Christopher Lemieux , Imran Ahmad , Nadia M. Bambace , Léa Bernard , Sandra Cohen , Jean-Sébastien Delisle , Isabelle Fleury , Thomas Kiss , Luigina Mollica , Denis-Claude Roy , Guy Sauvageau , Jean Roy , Sylvie Lachance
    DOI 10.1016/j.leukres.2019.01.002 PMID 30654975
    Consulter

  • Double-Negative T Cell Levels Correlate with Chronic Graft-versus-Host Disease Severity

    Erin E Hillhouse, Stéphanie Thiant, Moutuaata M Moutuou, Félix Lombard-Vadnais, Rachel Parat , Jean-Sébastien Delisle , Imran Ahmad , Denis-Claude Roy , Martin Guimond , Jean Roy , Sylvie Lesage
    DOI 10.1016/j.bbmt.2018.09.008 PMID 30244108
    Consulter

  • Proceedings From the Fourth Haploidentical Stem Cell Transplantation Symposium (HAPLO2016), San Diego, California, December 1, 2016

    Monzr M Al Malki, Richard Jones, Qing Ma, Dean Lee, Yair Reisner, Jeffrey S Miller, Peter Lang, Suradej Hongeng, Parameswaran Hari, Samuel Strober, Jianhua Yu, Richard Maziarz, Domenico Mavilio , Denis-Claude Roy , Chiara Bonini, Richard E Champlin, Ephraim J Fuchs, Stefan O Ciurea
    DOI 10.1016/j.bbmt.2018.01.008 PMID 29339270
    Consulter

  • The European Society for Blood and Marrow Transplantation (EBMT) Consensus Guidelines for the Detection and Treatment of Donor-specific Anti-HLA Antibodies (DSA) in Haploidentical Hematopoietic Cell Transplantation

    Stefan O. Ciurea, Kai Cao, Marcelo Fernandez-Vina, Piyanuch Kongtim, Monzr Al Malki, Ephraim Fuchs, Leo Luznik, Xiao-Jun Huang, Fabio Ciceri, Franco Locatelli, Franco Aversa, Luca Castagna , Andrea Bacigalupo, Massimo Martelli, Didier Blaise, Rupert Handgretinger , Denis-Claude Roy , Paul O’Donnell, Asad Bashey, Hillard M. Lazarus, Karen Ballen, Bipin N. Savani, Mohamad Mohty, Arnon Nagler
    DOI 10.1038/s41409-017-0062-8 PMID 29335625
    Consulter

  • Membrane permeabilizing amphiphilic peptide delivers recombinant transcription factor and CRISPR-Cas9/Cpf1 ribonucleoproteins in hard-to-modify cells

    Thomas Del'Guidice, Jean-Pascal Lepetit-Stoffaes, Louis-Jean Bordeleau, Joannie Roberge, Vanessa Théberge, Coraline Lauvaux, Xavier Barbeau, Jessica Trottier, Vibhuti Dave , Denis-Claude Roy , Bruno Gaillet, Alain Garnier, David Guay
    DOI 10.1371/journal.pone.0195558 PMID 29617431
    Consulter

  • Major vs minor histocompatibility antigens

    Denis-Claude Roy , Claude Perreault
    DOI 10.1182/blood-2016-12-754515 PMID 28183746
    Consulter

  • The IMPACT-CABG trial: A multicenter, randomized clinical trial of CD133+ stem cell therapy during coronary artery bypass grafting for ischemic cardiomyopathy

    Nicolas Noiseux, Samer Mansour, Richard Weisel, Louis-Mathieu Stevens, Shant Der Sarkissian, Katherine Tsang, Andrew M Crean, Eric Larose, Shu-Hong Li , Bernd Wintersperger, Minh Quan Vu, Ignacio Prieto, Ren-Ke Li , Denis-Claude Roy , Terrence M Yau
    DOI 10.1016/j.jtcvs.2016.07.067 PMID 27665225
    Consulter

  • Proteogenomic-based discovery of minor histocompatibility antigens with suitable features for immunotherapy of hematologic cancers

    D P Granados, A Rodenbrock, J-P Laverdure, C Côté, O Caron-Lizotte, C Carli, H Pearson, V Janelle, C Durette, E Bonneil , Denis-Claude Roy , Jean-Sébastien Delisle , S Lemieux, P Thibault, C Perreault
    DOI 10.1038/leu.2016.22 PMID 26857467
    Consulter

  • Proceedings from the Second Haploidentical Stem Cell Transplantation Symposium-Haplo2014, San Francisco, California, December 4, 2014

    Monzr M Al Malki, Mary Horowitz, Rupert Handgretinger, Wing Leung , Denis-Claude Roy , Xiao-Jun Huang, Ephraim Fuchs, Franco Locatelli, Didier Blaise, Shin Mineishi, Massimo Martelli, Jeffrey Miller, Carl June, Hui-Sheng Ai, Leo Luznik, Domenico Mavilio, Enrico Lugli, Marcel R M van den Brink, Richard E Champlin, Stefan O Ciurea
    DOI 10.1016/j.bbmt.2016.01.001 PMID 26806585
    Consulter

  • Favorable long-term outcome of patients with multiple myeloma using a frontline tandem approach with autologous and non-myeloablative allogeneic transplantation

    Imran Ahmad , Richard LeBlanc , Sandra Cohen , Sylvie Lachance , Thomas Kiss , Guy Sauvageau , Denis-Claude Roy , Lambert Busque , Jean-Sébastien Delisle , Nadia M Bambace , Léa Bernard , W Sabry , Jean Roy
    DOI 10.1038/bmt.2015.319 PMID 26691426
    Consulter

  • Impact of intracoronary injection of CD133+ bone marrow stem cells on coronary atherosclerotic progression in patients with STEMI: a COMPARE-AMI IVUS substudy

    Fuyu Qiu, Akiko Maehara, Ramez El Khoury, Philippe Généreux, Laura LaSalle, Gary S Mintz, Nicolas Noiseux , Denis-Claude Roy , François Gobeil, Louis-Mathieu Stevens, François Reeves, Guy Leclerc, Alain Rivard, Samer Mansour
    DOI 10.1097/MCA.0000000000000302 PMID 26340545
    Consulter

  • Early exposure to interleukin-21 limits rapidly generated anti-Epstein-Barr virus T-cell line differentiation

    Julie Orio, Cédric Carli, Valérie Janelle , Martin Giroux , Julie Taillefer, Mathieu Goupil, Manon Richaud , Denis-Claude Roy , Jean-Sébastien Delisle
    DOI 10.1016/j.jcyt.2014.12.009 PMID 25661862
    Consulter

  • CellCAN: a unique enabler of regenerative medicine and cell therapy in Canada

    Denis-Claude Roy , Anne-Marie Alarco, Rosario Isasi
    DOI 10.1089/scd.2014.0354 PMID 25457957
    Consulter

  • Harnessing the power of alloreactivity without triggering graft-versus-host disease: how non-engrafting alloreactive cellular therapy might change the landscape of acute myeloid leukemia treatment

    Elizabeth F Krakow , Julie Bergeron , Sylvie Lachance , Denis-Claude Roy , Jean-Sébastien Delisle
    DOI 10.1016/j.blre.2014.08.002 PMID 25228333
    Consulter

  • Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal

    Iman Fares, Jalila Chagraoui, Yves Gareau, Stéphane Gingras, Réjean Ruel, Nadine Mayotte, Elizabeth Csaszar, David J H F Knapp, Paul Miller, Mor Ngom, Suzan Imren , Denis-Claude Roy , Kori L Watts, Hans-Peter Kiem, Robert Herrington, Norman N Iscove, R Keith Humphries, Connie J Eaves , Sandra Cohen , Anne Marinier, Peter W Zandstra , Guy Sauvageau
    DOI 10.1126/science.1256337 PMID 25237102
    Consulter

  • Medium conditioned with mesenchymal stromal cell-derived osteoblasts improves the expansion and engraftment properties of cord blood progenitors

    Nellie Dumont, Lucie Boyer, Hélène Émond, Betül Celebi-Saltik, Roya Pasha, Renée Bazin, Diego Mantovani , Denis-Claude Roy , Nicolas Pineault
    DOI 10.1016/j.exphem.2014.04.009 PMID 24793546
    Consulter

  • Inability of HOXB4 to enhance self-renewal of malignant B cells: favorable profile for the expansion of autologous hematopoietic stem cells

    Marilaine Fournier, Isabelle Savoie-Rondeau, Fannie Larochelle, Mona Hassawi, Elena A Shestakova , Denis-Claude Roy , Janetta J Bijl
    DOI 10.1016/j.exphem.2014.01.011 PMID 24503485
    Consulter

  • Policy recommendations for addressing privacy challenges associated with cell-based research and interventions

    Ubaka Ogbogu, Sarah Burningham, Adam Ollenberger, Kathryn Calder, Li Du, Khaled El Emam, Robyn Hyde-Lay, Rosario Isasi, Yann Joly, Ian Kerr, Bradley Malin, Michael McDonald, Steven Penney, Gayle Piat , Denis-Claude Roy , Jeremy Sugarman, Suzanne Vercauteren, Griet Verhenneman, Lori West, Timothy Caulfield
    DOI 10.1186/1472-6939-15-7 PMID 24485220
    Consulter

  • Reply to letter from Kopjar et al.-the IMPACT-CABG Pilot Trial

    Nicolas Noiseux, Louis-Mathieu Stevens, Ignacio Prieto, Reda Salem , Denis-Claude Roy , Eric Larose, Samer Mansour
    DOI 10.1016/j.cjca.2013.03.016 PMID 23725864
    Consulter

  • Bcl-xL anti-apoptotic network is dispensable for development and maintenance of CML but is required for disease progression where it represents a new therapeutic target

    J G Harb 1, P Neviani, B J Chyla, J J Ellis, G J Ferenchak, J J Oaks, C J Walker, P Hokland , Denis-Claude Roy , M A Caligiuri, G Marcucci, C S Huettner, D Perrotti
    DOI 10.1038/leu.2013.151 PMID 23670294
    Consulter

  • Preclinical and clinical efficacy of XPO1/CRM1 inhibition by the karyopherin inhibitor KPT-330 in Ph+ leukemias

    Christopher J. Walker, Joshua J. Oaks, Ramasamy Santhanam, Paolo Neviani, Jason G. Harb, Gregory Ferenchak, Justin J. Ellis, Yosef Landesman, Ann-Kathrin Eisfeld, Nash Y. Gabrail, Carrie L. Smith, Michael A. Caligiuri, Peter Hokland , Denis-Claude Roy , Alistair Reid, Dragana Milojkovic, John M. Goldman, Jane Apperley, Ramiro Garzon, Guido Marcucci, Sharon Shacham, Michael G. Kauffman, Danilo Perrotti
    DOI 10.1182/blood-2013-04-495374 PMID 23970380
    Consulter

  • Transplantation of mesenchymal stem cells promotes tissue regeneration in a glaucoma model through laser-induced paracrine factor secretion and progenitor cell recruitment

    Renaud Manuguerra-Gagné, Patrick R Boulos, Ahmed Ammar, François A Leblond, Gorazd Krosl, Vincent Pichette, Mark R Lesk , Denis-Claude Roy
    DOI 10.1002/stem.1364 PMID 23495088
    Consulter

  • Implantation of CD133+ stem cells in patients undergoing coronary bypass surgery: IMPACT-CABG pilot trial

    Jessica Forcillo, Louis-Mathieu Stevens, Samer Mansour, Ignacio Prieto, Reda Salem, Chantal Baron , Denis-Claude Roy , Eric Larose, Daiana Masckauchan, Nicolas Noiseux
    DOI 10.1016/j.cjca.2012.08.009 PMID 23265095
    Consulter

  • Safety and cost-effectiveness of outpatient autologous stem cell transplantation in patients with multiple myeloma

    Andreas Holbro , Imran Ahmad , Sandra Cohen , Jean Roy , Sylvie Lachance , Miguel Chagnon , Richard LeBlanc , Léa Bernard , Lambert Busque , Denis-Claude Roy , Guy Sauvageau , Thomas Kiss
    DOI 10.1016/j.bbmt.2012.12.006 PMID 23253556
    Consulter

  • Selective T-cell depletion for haplotype-mismatched allogeneic stem cell transplantation

    Jean-Philippe Bastien , Jean Roy , Denis-Claude Roy
    DOI 10.1053/j.seminoncol.2012.09.004 PMID 23206844
    Consulter

  • Cotransplantation of ex vivo expanded progenitors with nonexpanded cord blood cells improves platelet recovery

    Hélène Émond, Lucie Boyer , Denis-Claude Roy , Nicolas Pineault
    DOI 10.1089/scd.2012.0142 PMID 22783996
    Consulter

  • Preconditioning of stem cells by oxytocin to improve their therapeutic potential

    Nicolas Noiseux, Mélanie Borie, Alexandra Desnoyers, Ahmed Menaouar, Louis Mathieu Stevens, Samer Mansour, Bogdan A Danalache , Denis-Claude Roy , Marek Jankowski, Jolanta Gutkowska
    DOI 10.1210/en.2012-1402 PMID 23024264
    Consulter

  • Tandem autologous-allogeneic nonmyeloablative sibling transplantation in relapsed follicular lymphoma leads to impressive progression-free survival with minimal toxicity

    Sandra Cohen , Thomas Kiss , Sylvie Lachance , Denis-Claude Roy , Guy Sauvageau , Lambert Busque , Imran Ahmad , Jean Roy
    DOI 10.1016/j.bbmt.2011.11.028 PMID 22155507
    Consulter

  • Distinct but phenotypically heterogeneous human cell populations produce rapid recovery of platelets and neutrophils after transplantation

    Alice M S Cheung, Donna Leung, Shabnam Rostamirad, Kiran Dhillon, Paul H Miller, Radina Droumeva, Ryan R Brinkman, Donna Hogge , Denis-Claude Roy , Connie J Eaves
    DOI 10.1182/blood-2011-12-398024 PMID 22374695
    Consulter

  • Cardiac tamponade potentially related to sirolimus following cord blood transplantation

    A Holbro , Imran Ahmad , Lambert Busque , Sandra Cohen , Sylvie Lachance , Denis-Claude Roy , Jean Roy , Guy Sauvageau , Thomas Kiss
    DOI 10.1038/bmt.2011.44 PMID 21399672
    Consulter

  • Incidence and prognostic value of eosinophilia in chronic graft-versus-host disease after nonmyeloablative hematopoietic cell transplantation

    Imran Ahmad , Annie-Claude Labbé, Miguel Chagnon , Lambert Busque , Sandra Cohen , Thomas Kiss , Sylvie Lachance , Denis-Claude Roy , Guy Sauvageau , Jean Roy
    DOI 10.1016/j.bbmt.2011.04.012 PMID 21601640
    Consulter

  • Next-generation leukemia immunotherapy

    Krystel Vincent , Denis-Claude Roy , Claude Perreault
    DOI 10.1182/blood-2011-04-350868 PMID 21734234
    Consulter

  • IMPACT-CABG Trial: Implantation of CD133(+) Stem Cells in Patients Undergoing Coronary Bypass Surgery-Presentation of the First Treated Patient

    Jessica Forcillo, Louis-Mathieu Stevens, Samer Mansour, Ignacio Prieto , Denis-Claude Roy , Nicolas Noiseux
    DOI 10.1155/2011/685394 PMID 23213603
    Consulter

  • Individual and synergistic cytokine effects controlling the expansion of cord blood CD34(+) cells and megakaryocyte progenitors in culture

    Nicolas Pineault, Valérie Cortin, Lucie Boyer, Alain Garnier, Amélie Robert, Cynthia Thérien , Denis-Claude Roy
    DOI 10.3109/14653249.2010.530651 PMID 21090916
    Consulter

  • COMPARE-AMI trial: comparison of intracoronary injection of CD133+ bone marrow stem cells to placebo in patients after acute myocardial infarction and left ventricular dysfunction: study rationale and design

    Samer Mansour , Denis-Claude Roy , Vincent Bouchard, Ba Khoi Nguyen, Louis Mathieu Stevens, Francois Gobeil, Alain Rivard, Guy Leclerc, François Reeves, Nicolas Noiseux
    DOI 10.1007/s12265-009-9145-2 PMID 20560029
    Consulter

  • One-Year Safety Analysis of the COMPARE-AMI Trial: Comparison of Intracoronary Injection of CD133 Bone Marrow Stem Cells to Placebo in Patients after Acute Myocardial Infarction and Left Ventricular Dysfunction

    Samer Mansour , Denis-Claude Roy , Vincent Bouchard, Louis Mathieu Stevens, Francois Gobeil, Alain Rivard, Guy Leclerc, François Reeves, Nicolas Noiseux
    DOI 10.1155/2011/385124 PMID 22046562
    Consulter

  • Photodepletion differentially affects CD4+ Tregs versus CD4+ effector T cells from patients with chronic graft-versus-host disease

    Jean-Philippe Bastien 1, Gorazd Krosl, Cynthia Therien, Marissa Rashkovan, Christian Scotto , Sandra Cohen , David S Allan, Donna Hogge, R Maarten Egeler, Claude Perreault , Denis-Claude Roy
    DOI 10.1182/blood-2010-03-273193 PMID 20798236
    Consulter

  • Late acute renal failure due to bilateral kidney infiltration by ALL as single manifestation of relapse after allogeneic transplantation

    M Detrait, C Meunier , Denis-Claude Roy , Thomas Kiss , Sylvie Lachance , Sandra Cohen , Lambert Busque , Guy Sauvageau , Jean Roy
    DOI 10.1038/bmt.2009.246 PMID 19767785
    Consulter

  • miR-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts

    Anna M Eiring, Jason G Harb, Paolo Neviani, Christopher Garton, Joshua J Oaks, Riccardo Spizzo, Shujun Liu, Sebastian Schwind, Ramasamy Santhanam, Christopher J Hickey, Heiko Becker , Jason C Chandler, Raul Andino, Jorge Cortes, Peter Hokland, Claudia S Huettner, Ravi Bhatia , Denis-Claude Roy , Stephen A Liebhaber, Michael A Caligiuri, Guido Marcucci, Ramiro Garzon, Carlo M Croce, George A Calin, Danilo Perrotti
    DOI 10.1016/j.cell.2010.01.007 PMID 20211135
    Consulter

  • Stem cell therapy for the broken heart: mini-organ transplantation

    S Mansour , Denis-Claude Roy , B Lemieux, C Ouellet, L-M Stevens, N Noiseux
    DOI 10.1016/j.transproceed.2009.08.033 PMID 19857748
    Consulter

  • No association between telomere length and blood cell counts in elderly individuals

    Luigina Mollica , Isabelle Fleury , Claude Belisle, Sylvie Provost , Denis-Claude Roy , Lambert Busque
    DOI 10.1093/gerona/glp065 PMID 19435952
    Consulter

  • Graft-versus-host disease prophylaxis with tacrolimus and mycophenolate mofetil in HLA-matched nonmyeloablative transplant recipients is associated with very low incidence of GVHD and nonrelapse mortality

    Waleed Sabry , Richard LeBlanc , Annie-Claude Labbé , Guy Sauvageau , Stephen Couban , Thomas Kiss , Lambert Busque , Sandra Cohen , Sylvie Lachance , Denis-Claude Roy , Jean Roy
    DOI 10.1016/j.bbmt.2009.04.004 PMID 19589481
    Consulter

  • Molecular targeting of the oncogene eIF4E in acute myeloid leukemia (AML): a proof-of-principle clinical trial with ribavirin

    Sarit Assouline, Biljana Culjkovic, Eftihia Cocolakis, Caroline Rousseau, Nathalie Beslu, Abdellatif Amri, Stephen Caplan, Brian Leber , Denis-Claude Roy , Wilson H Miller Jr, Katherine L B Borden
    DOI 10.1182/blood-2009-02-205153 PMID 19433856
    Consulter

  • Diphyllobothriasis, a rare cause of profuse diarrhea following autologous transplantation

    M Detrait, L Poirier , Denis-Claude Roy , Thomas Kiss , Lambert Busque , Sandra Cohen , Sylvie Lachance , Guy Sauvageau , Jean Roy
    DOI 10.1038/bmt.2008.439 PMID 19169286
    Consulter

  • An automated system for delivery of an unstable transcription factor to hematopoietic stem cell cultures

    Elizabeth Csaszar, Geneviève Gavigan, Mark Ungrin, Cynthia Thérien, Pascale Dubé, James Féthière , Guy Sauvageau , Denis-Claude Roy , Peter W Zandstra
    DOI 10.1002/bit.22297 PMID 19266473
    Consulter

  • Skewing of X-inactivation ratios in blood cells of aging women is confirmed by independent methodologies

    Lambert Busque , Yves Paquette, Sylvie Provost , Denis-Claude Roy , Ross L Levine , Luigina Mollica , D Gary Gilliland
    DOI 10.1182/blood-2008-12-195677 PMID 19202126
    Consulter

  • Telomere length is severely and similarly reduced in JAK2V617F-positive and -negative myeloproliferative neoplasms

    Léa Bernard , C Belisle , Luigina Mollica , S Provost , Denis-Claude Roy , D G Gilliland, R L Levine , Lambert Busque
    DOI 10.1038/leu.2008.319 PMID 19005480
    Consulter

  • Evidence suggesting the presence of a stem cell clone anteceding the acquisition of the JAK2-V617F mutation

    R Jamal, C Bélisle, M-C Lessard , Josée Hébert , Denis-Claude Roy , R Levine , Lambert Busque
    DOI 10.1038/leu.2008.6 PMID 18239619
    Consulter

  • Hb Montreal II: a novel elongated beta-globin variant caused by a frameshift mutation [beta142 (-C)]

    Pierre Chagnon , Luigina Mollica , Claude Belisle, Céline Deveaux, Giovanni D Angelo , Denis-Claude Roy , Denis Soulières , Lambert Busque
    DOI 10.1080/03630260802173593 PMID 18654885
    Consulter

  • High incidence of invasive aspergillosis associated with intestinal graft-versus-host disease following nonmyeloablative transplantation

    Annie-Claude Labbé, Shi Hann Su, Michel Laverdière, Jacques Pépin, Carlos Patiño , Sandra Cohen , Thomas Kiss , Sylvie Lachance , Guy Sauvageau , Lambert Busque , Denis-Claude Roy , Jean Roy
    DOI 10.1016/j.bbmt.2007.06.013 PMID 17889356
    Consulter

  • High levels of the BCR/ABL oncoprotein are required for the MAPK-hnRNP-E2 dependent suppression of C/EBPalpha-driven myeloid differentiation

    Ji Suk Chang, Ramasamy Santhanam, Rossana Trotta, Paolo Neviani, Anna M Eiring, Edward Briercheck, Mattia Ronchetti , Denis-Claude Roy , Bruno Calabretta, Michael A Caligiuri, Danilo Perrotti
    DOI 10.1182/blood-2007-03-078303 PMID 17475908
    Consulter

  • FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome-positive acute lymphocytic leukemia

    Paolo Neviani, Ramasamy Santhanam, Joshua J Oaks, Anna M Eiring, Mario Notari, Bradley W Blaser, Shujun Liu, Rossana Trotta, Natarajan Muthusamy, Carlo Gambacorti-Passerini, Brian J Druker, Jorge Cortes, Guido Marcucci, Ching-Shih Chen, Nicole M Verrills , Denis-Claude Roy , Michael A Caligiuri, Clara D Bloomfield, John C Byrd, Danilo Perrotti
    DOI 10.1172/JCI31095 PMID 17717597
    Consulter

  • Endothelial-like vascular progenitor cells (VPCs) from allogeneic and autologous donors: mobilization features distinct from hematopoietic progenitors

    David S Allan, Pascale Dubé , Jean Roy , Lambert Busque , Denis-Claude Roy
    DOI 10.1016/j.bbmt.2006.11.016 PMID 17382249
    Consulter

  • Prediction of graft-versus-host disease in humans by donor gene-expression profiling

    Chantal Baron, Roland Somogyi, Larry D Greller, Vincent Rineau, Peter Wilkinson, Carolyn R Cho, Mark J Cameron, David J Kelvin, Pierre Chagnon , Denis-Claude Roy , Lambert Busque , Rafick-Pierre Sékaly, Claude Perreault
    DOI 10.1371/journal.pmed.0040023 PMID 17378698
    Consulter

  • Recommendations of the canadian consensus group on the management of chronic myeloid leukemia

    P Laneuville, M J Barnett, R Bélanger, S Couban, D L Forrest , Denis-Claude Roy , J H Lipton
    PMID 22792021
    Consulter

  • What is the clinical significance of infusing hematopoietic cell grafts contaminated with bacteria?

    M Kelly , Denis-Claude Roy , A C Labbe, M Laverdiere
    DOI 10.1038/sj.bmt.1705421 PMID 16785868
    Consulter

  • A MAPK/HNRPK pathway controls BCR/ABL oncogenic potential by regulating MYC mRNA translation

    Mario Notari, Paolo Neviani, Ramasamy Santhanam, Bradley W Blaser, Ji-Suk Chang, Annamaria Galietta, Anne E Willis , Denis-Claude Roy , Michael A Caligiuri, Guido Marcucci, Danilo Perrotti
    DOI 10.1182/blood-2005-09-3732 PMID 16293596
    Consulter

  • Evidence that donor intrinsic response to G-CSF is the best predictor of acute graft-vs-host disease following allogeneic peripheral blood stem cell transplantation

    Nathalie Dhédin, Inès Chamakhi, Claude Perreault , Denis-Claude Roy , Guy Sauvageau , Thierry Ducruet , Lambert Busque , Douglas Fish, Robert Bélanger , Jean Roy
    DOI 10.1016/j.exphem.2005.09.013 PMID 16413397
    Consulter

  • The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein

    Paolo Neviani, Ramasamy Santhanam, Rossana Trotta, Mario Notari, Bradley W Blaser, Shujun Liu, Hsiaoyin Mao, Ji Suk Chang, Annamaria Galietta, Ashwin Uttam , Denis-Claude Roy , Mauro Valtieri, Rebecca Bruner-Klisovic, Michael A Caligiuri, Clara D Bloomfield, Guido Marcucci, Danilo Perrotti
    DOI 10.1016/j.ccr.2005.10.015 PMID 16286244
    Consulter

  • Elimination of alloreactive T cells using photodynamic therapy

    Radia Sidi Boumédine , Denis-Claude Roy
    DOI 10.1080/14653240510027109 PMID 16040392
    Consulter

  • Maintaining high autopsy rates in a Canadian blood and marrow transplant program: preserving a diagnostic and research tool

    D S Allan, R Bélanger , Lambert Busque , Sandra Cohen , D Fish , Denis-Claude Roy , Jean Roy
    DOI 10.1038/sj.bmt.1704869 PMID 15735662
    Consulter

  • Vascular leak syndrome and serositis as an unusual manifestation of chronic graft-versus-host disease in nonmyeloablative transplants

    M Gyger, A Rosenberg, A Shamy, A Hercz, S Caplan, I A Sebag, M L Brisson , Denis-Claude Roy
    DOI 10.1038/sj.bmt.1704730 PMID 15558044
    Consulter

  • Evidence for adequate thymic function but impaired naive T-cell survival following allogeneic hematopoietic stem cell transplantation in the absence of chronic graft-versus-host disease

    Jean-François Poulin, Myriam Sylvestre, Patrick Champagne, Marie-Lise Dion, Nadia Kettaf, Alain Dumont, Maryse Lainesse, Pierre Fontaine , Denis-Claude Roy , Claude Perreault, Rafick-Pierre Sékaly, Rémi Cheynier
    DOI 10.1182/blood-2003-05-1428 PMID 12933579
    Consulter

  • Oncogenic interaction between BCR-ABL and NUP98-HOXA9 demonstrated by the use of an in vitro purging culture system

    Nadine Mayotte , Denis-Claude Roy , Jing Yao, Evert Kroon , Guy Sauvageau
    DOI 10.1182/blood-2002-04-1244 PMID 12393433
    Consulter

  • P-glycoprotein targeting: a unique strategy to selectively eliminate immunoreactive T cells

    Martin Guimond, Antonia Balassy, Mélanie Barrette, Sylvie Brochu, Claude Perreault , Denis-Claude Roy
    DOI 10.1182/blood-2001-12-0353 PMID 12091325
    Consulter

  • Allogeneic transplantation for multiple myeloma: further evidence for a GVHD-associated graft-versus-myeloma effect

    Richard LeBlanc , S Montminy-Métivier, R Bélanger , Lambert Busque , D Fish , Denis-Claude Roy , Jeannine Kassis , J Boileau, R Lavallée, D Bélanger, F Letendre , Josée Hébert , Guy Sauvageau , C Perreault , Jean Roy
    DOI 10.1038/sj.bmt.1703253 PMID 11781644
    Consulter

  • Adoptive transfer of minor histocompatibility antigen-specific T lymphocytes eradicates leukemia cells without causing graft-versus-host disease

    P Fontaine, G Roy-Proulx, L Knafo, C Baron , Denis-Claude Roy , C Perreault
    DOI 10.1038/89907 PMID 11433342
    Consulter

  • Relapse after bone marrow transplantation: evidence for distinct immunological mechanisms between adult and paediatric populations

    M Guimond , Lambert Busque , C Baron, Y Bonny, R Bélanger, J Mattioli, C Perreault , Denis-Claude Roy
    DOI 10.1046/j.1365-2141.2000.01961.x PMID 10848792
    Consulter

  • The in vivo fate of APCs displaying minor H antigen and/or MHC differences is regulated by CTLs specific for immunodominant class I-associated epitopes

    V Loyer, P Fontaine, S Pion, F Hétu , Denis-Claude Roy , C Perreault
    PMID 10586037
    Consulter

  • Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

    W J Song, M G Sullivan, R D Legare, S Hutchings, X Tan, D Kufrin, J Ratajczak, I C Resende, C Haworth, R Hock, M Loh, C Felix , Denis-Claude Roy , Lambert Busque , D Kurnit, C Willman, A M Gewirtz, N A Speck, J H Bushweller, F P Li, K Gardiner, M Poncz, J M Maris, D G Gilliland
    DOI 10.1038/13793 PMID 10508512
    Consulter

  • Massive activation-induced cell death of alloreactive T cells with apoptosis of bystander postthymic T cells prevents immune reconstitution in mice with graft-versus-host disease

    S Brochu, B Rioux-Massé , Jean Roy , Denis-Claude Roy , C Perreault
    PMID 10397705
    Consulter

  • The effect of graft-versus-host disease on T cell production and homeostasis

    G Dulude , Denis-Claude Roy , C Perreault
    DOI 10.1084/jem.189.8.1329 PMID 10209049
    Consulter

  • Quantitative assessment of hematopoietic chimerism after allogeneic bone marrow transplantation has predictive value for the occurrence of irreversible graft failure and graft-vs.-host disease

    M Gyger, C Baron, L Forest, P Lussier, F Lagacé, I Bissonnette, R Bélanger, Y Bonny , Lambert Busque , Denis-Claude Roy , C Perreault
    PMID 9590660
    Consulter

  • Immunodominant minor histocompatibility antigens: the major ones

    C Perreault , Denis-Claude Roy , C Fortin
    DOI 10.1016/s0167-5699(97)01185-7 PMID 9509761
    Consulter

  • Lymphoma cell burden in progenitor cell grafts measured by competitive polymerase chain reaction: less than one log difference between bone marrow and peripheral blood sources

    B M Léonard, F Hétu , Lambert Busque , M Gyger, R Bélanger, C Perreault , Denis-Claude Roy
    PMID 9414302
    Consulter

  • Conjugation of blocked ricin to an anti-CD19 monoclonal antibody increases antibody-induced cell calcium mobilization and CD19 internalization

    A C Goulet, V S Goldmacher, J M Lambert, C Baron , Denis-Claude Roy , E Kouassi
    PMID 9310487
    Consulter

  • Thymic and extrathymic differentiation and expansion of T lymphocytes following bone marrow transplantation in irradiated recipients

    G Dulude, S Brochu, P Fontaine, C Baron, M Gyger , Denis-Claude Roy , C Perreault
    PMID 9257813
    Consulter

  • Elimination of neuroblastoma and small-cell lung cancer cells with an anti-neural cell adhesion molecule immunotoxin

    Denis-Claude Roy , S Ouellet, C Le Houillier, P D Ariniello, C Perreault, J M Lambert
    DOI 10.1093/jnci/88.16.1136 PMID 8757193
    Consulter

  • Identification of an immunodominant mouse minor histocompatibility antigen (MiHA). T cell response to a single dominant MiHA causes graft-versus-host disease

    C Perreault, J Jutras , Denis-Claude Roy , J G Filep, S Brochu
    DOI 10.1172/JCI118832 PMID 8698852
    Consulter

  • Sequential analysis of early hematopoietic reconstitution following allogeneic bone marrow transplantation with fluorescence in situ hybridization (FISH)

    C Lapointe, L Forest, P Lussier , Lambert Busque , F Lagace, C Perreault , Denis-Claude Roy , M Gyger
    PMID 8807127
    Consulter

  • Flow cytometric evaluation of leukocyte subpopulations in the follicular fluids of infertile patients

    M H Lachapelle, R Hemmings , Denis-Claude Roy , T Falcone, P Miron
    DOI 10.1016/s0015-0282(16)58327-7 PMID 8641486
    Consulter

  • Endometrial T, B, and NK cells in patients with recurrent spontaneous abortion. Altered profile and pregnancy outcome

    M H Lachapelle, P Miron, R Hemmings , Denis-Claude Roy
    PMID 8621945
    Consulter

  • Phenotypic and functional characterization of peripheral blood and bone marrow natural killer cells prior to autologous transplantation

    S Arbour, S Toupin, R Bélanger, M Gyger, J P Hallé, C Perreault , Denis-Claude Roy
    PMID 8704680
    Consulter

  • Flow-cytometric characterization of hematopoietic cells in non-pregnant human endometrium

    M H Lachapelle, P Miron, R Hemmings, C Baron , Denis-Claude Roy
    DOI 10.1111/j.1600-0897.1996.tb00002.x PMID 8789553
    Consulter

  • Oligoclonal expansion of CTLs directed against a restricted number of dominant minor histocompatibility antigens in hemopoietic chimeras

    S Brochu, C Baron, F Hétu , Denis-Claude Roy , C Perreault
    PMID 7594519
    Consulter

  • Distinct patterns of minimal residual disease associated with graft-versus-host disease after allogeneic bone marrow transplantation for chronic myelogenous leukemia

    G Pichert , Denis-Claude Roy , R Gonin, E P Alyea, R Bélanger, M Gyger, C Perreault, Y Bonny, I Lerra, C Murray
    DOI 10.1200/JCO.1995.13.7.1704 PMID 7602361
    Consulter

  • Elimination of B-lineage leukemia and lymphoma cells from bone marrow grafts using anti-B4-blocked-ricin immunotoxin

    Denis-Claude Roy , C Perreault, R Bélanger, M Gyger, C Le Houillier, W A Blättler, J M Lambert, J Ritz
    DOI 10.1007/BF01489490 PMID 7539011
    Consulter

  • A non-isotopic nested polymerase chain reaction method to quantitate minimal residual disease in patients with non-Hodgkin's lymphoma

    F Hétu, F Coutlée , Denis-Claude Roy
    DOI 10.1006/mcpr.1994.1064 PMID 7700265
    Consulter

  • Persistence of myeloid progenitor cells expressing BCR-ABL mRNA after allogeneic bone marrow transplantation for chronic myelogenous leukemia

    G Pichert, E P Alyea, R J Soiffer , Denis-Claude Roy , J Ritz
    PMID 7919323
    Consulter

  • Allogeneic bone marrow transplantation following busulfan-cyclophosphamide with or without etoposide conditioning regimen for patients with acute lymphoblastic leukaemia

    Anne von Bueltzingsloewen, Robert Bélanger, Claude Perreault, Yvette Bonny , Denis-Claude Roy , Jacques Boileau , Jeannine Kassis , René Lavallée, Michel Lacombe, Martin Gyger
    DOI 10.1111/j.1365-2141.1993.tb03212.x PMID 7918033
    Consulter

  • Acute graft-versus-host disease prophylaxis with methotrexate and cyclosporine after busulfan and cyclophosphamide in patients with hematologic malignancies

    Anne von Bueltzingsloewen, Robert Belanger, Claude Perreault, Yvette Bonny , Denis-Claude Roy , Yves Lalonde, Jacques Boileau , Jeannine Kassis , Rene Lavallee, Michel Lacombe, Martin Gyger
    PMID 8427977
    Consulter

  • Tolerance to host minor histocompatibility antigens after allogenic bone marrow transplantation. Specific donor-host unresponsiveness is maintained by peripheral tolerizing cells

    S Brochu , Denis-Claude Roy , C Perreault
    PMID 1431092
    Consulter

  • Immunologic purging of marrow assessed by PCR before autologous bone marrow transplantation for B-cell lymphoma

    John G. Gribben, Arnold S. Freedman, Donna Neuberg , Denis-Claude Roy , Kelly W. Blake, Sunhee D. Woo, Michael L. Grossbard, Susan N. Rabinowe., Felice Coral, Gordon J. Freeman, Jerome Ritz, Lee M. Nadler
    DOI 10.1056/NEJM199111283252201 PMID 1944436
    Consulter

  • Pulmonary alveolar microlithiasis

    S K Agarwal , Denis-Claude Roy , A Johri
    PMID 1795121
    Consulter

  • Critical issues in bone marrow transplantation immunology

    C Perreault, R Bélanger, Y Bonny, M Gyger , Denis-Claude Roy
    PMID 2043881
    Consulter

  • Anti-MY9-blocked-ricin: an immunotoxin for selective targeting of acute myeloid leukemia cells

    Denis-Claude Roy , J D Griffin, M Belvin, W A Blättler, J M Lambert, J Ritz
    PMID 2039821
    Consulter

  • Minor histocompatibility antigens

    Claude Perreault, Francine Decary, Sylvie Brochu, Martin Gyger, Robert Belanger , Denis-Claude Roy
    PMID 2207305
    Consulter

  • Comparative activities of rabbit complements of different ages using an in-vitro marrow purging model

    Denis-Claude Roy , M Felix, W G Cannady, S Cannistra, J Ritz
    DOI 10.1016/0145-2126(90)90026-6 PMID 2345466
    Consulter

  • Evaluating respiratory allergy in Varanasi and environs

    Denis-Claude Roy , J K Mishra
    PMID 2292392
    Consulter

  • Electrocardiographic abnormalities in tropical pulmonary eosinophilia

    S K Agarwal , Denis-Claude Roy , A Johri
    PMID 2148545
    Consulter

  • Natural history of mixed chimerism after bone marrow transplantation with CD6-depleted allogeneic marrow: a stable equilibrium

    Denis-Claude Roy , Ramana Tantravahi, Christine Murray, Keith Dear, Barbara Gorgone, Kenneth C. Anderson, Arnold S. Freedman, Lee M. Nadler, Jerome Ritz
    PMID 1967216
    Consulter

  • Importance of smoking index for assessing lung damage by lung function tests

    A K De, M M Tripathi, S C Matah , Denis-Claude Roy
    PMID 2638652
    Consulter

  • Unilateral recurrent pneumothorax complicating rheumatoid lung

    S K Agarwal , Denis-Claude Roy , R Pandey
    PMID 2600437
    Consulter

  • Profile of serum transaminases in acute bronchial asthma

    J K Samaria , Denis-Claude Roy , B V Agarwal, S C Matah
    PMID 3596655
    Consulter

  • Short course intermittent chemotherapy in pulmonary tuberculosis

    S K Agarwal , Denis-Claude Roy , S Sundar, S C Matah
    PMID 4030678
    Consulter

  • Empyema thoracis: a review of 70 cases

    S K Agarwal , Denis-Claude Roy , N Jha
    PMID 3837752
    Consulter

  • Pleural irrigation in the management of empyema thoracis

    S K Agarwal , Denis-Claude Roy , N Jha
    PMID 3837753
    Consulter