Passer au contenu principal
Centre intégré universitaire de santé
et de services sociaux de l'Est-de-l'Île-de-Montréal

Centre intégré universitaire de santé et de services sociaux de l'Est-de-l'Île-de-Montréal

Lambert Busque, M.D.

Lambert Busque

Hématologue, Professeur titulaire

L'équipe de l’IHOT

Chercheur-clinicien

Contact

Tél. : 514 252-3404

Les intérêts de recherche du Dr Lambert Busque portent sur la caractérisation des causes moléculaires du développement de l’hématopoïèse clonale associée au vieillissement, l’immunothérapie du cancer et la recherche clinique en cancers myéloïdes.

 

  • Chef du service de diagnostic moléculaire clinique HMR
  • Directeur de l'unité de recherche en Hématopoïèse et vieillissement du Centre de recherche HMR
  • Membre du Comité de direction de l'IHOT
  • Président du Groupe québécois de recherche sur la LMC et les NMP (GQR-LMC/NMP)
  • Chef médical du Centre C3i (commercialisation en immunothérapie du cancer)
  • Entrée en poste à l’Hôpital Maisonneuve-Rosemont : 1994

 

Formation :

  • Fellowship en biologie moléculaire : Harvard Medical School de Boston (États-Unis), 1992-1994
  • Résidences en médecine interne et hématologie : Université de Montréal (Canada), 1986-1991
  • Doctorat en médecine : Université de Montréal (Canada), 1981-1986

Découvrez ses publications

  • Length: Cardiac Vagal Activity Influences the Relation in Older Adults

    Alexandra Connor, Alain Deschamps , Lambert Busque , Jean-Claude Tardif, Vincent Bourgoin, Marie-Pierre Dubé, David Busseuil, Bianca D'Antono
    DOI 10.1097/PSY.0000000000001290 PMID 38345296
    Consulter

  • CALR mutation burden in essential thrombocythemia and disease outcome

    Paola Guglielmelli , Natasha Szuber , Naseema Gangat, Giulio Capecchi, Chiara Maccari, Michaël Harnois, Omer Karrar, Maymona Abdelmagid, Manjola Balliu, Elena Nacca, Alessandro Atanasio, Ilaria Sestini, Audrey Désilets, Giuseppe Gaetano Loscocco, Giada Rotunno , Lambert Busque , Ayalew Tefferi, Alessandro Maria Vannucchi
    DOI 10.1182/blood.2023023428 PMID 38252902
    Consulter

  • The PGK-PCR clonality assay (PPCA)

    Lambert Busque , D G Gilliland
    DOI 10.1385/0-89603-258-2:237 PMID 7921021
    Consulter

  • Oral decitabine-cedazuridine versus intravenous decitabine for myelodysplastic syndromes and chronic myelomonocytic leukaemia (ASCERTAIN): a registrational, randomised, crossover, pharmacokinetics, phase 3 study

    Guillermo Garcia-Manero, James McCloskey, Elizabeth A Griffiths, Karen W L Yee, Amer M Zeidan, Aref Al-Kali, H Joachim Deeg, Prapti A Patel, Mitchell Sabloff, Mary-Margaret Keating , Nancy Zhu, Nashat Y Gabrail, Salman Fazal, Joseph Maly, Olatoyosi Odenike, Hagop Kantarjian, Amy E DeZern, Casey L O'Connell, Gail J Roboz , Lambert Busque , Rena Buckstein, Harshad Amin, Jasleen Randhawa, Brian Leber, Aditi Shastri, Kim-Hien Dao, Aram Oganesian, Yong Hao, Harold N Keer, Mohammad Azab, Michael R Savona
    DOI 10.1016/S2352-3026(23)00338-1 PMID 38135371
    Consulter

  • Final report of TKI discontinuation trial with dasatinib for the second attempt of treatment-free remission after failing the first attempt with imatinib: Treatment-free Remission Accomplished by Dasatinib (TRAD) study

    Maria Agustina Perusini, Igor Novitzky-Basso, Eshetu G. Atenafu, Donna Forrest, Isabelle Bence-Bruckler, Lynn Savoie, Mary-Margaret Keating , Lambert Busque , Robert Delage, Anargyros Xenocostas, Elena Liew, Pierre Laneuville, Kristjan Paulson, Tracy Stockley, Jeffrey H. Lipton, Brian Leber, Dennis Dong Hwan Kim
    DOI 10.1111/bjh.19058 PMID 37697469
    Consulter

  • Risk of progression in chronic phase-chronic myeloid leukemia patients eligible for tyrosine kinase inhibitor discontinuation: Final analysis of the TFR-PRO study

    Giovanni Paolo Maria Zambrotta, Franck E. Nicolini, Sarit Assouline , Lambert Busque , Ester Pungolino, Elisabetta Abruzzese, Maria Cristina Miggiano, Chiara Elena, Alberto Alvarez-Larran, Ana Triguero, Alessandra Iurlo, Cristina Bucelli, Marco Cerrano, Isabella Capodanno, Francesca Lunghi , Philipp le Coutre, Sara Galimberti, Giovanni Caocci, Margherita Maffioli, Fabio Stagno, Susanne Saussele, Rocco Piazza, Brian J. Druker, Carmen Fava, Veronica Guglielmana , Federica Colombo, Laura Antolini, Carlo Gambacorti-Passerini
    DOI 10.1002/ajh.27073 PMID 37647134
    Consulter

  • Canadian real-world experience of asciminib treatment in heavily pre-treated chronic myeloid leukemia (CML) patients who failed multiple lines of tyrosine kinase inhibitor (TKI) therapy

    Fatima M Khadadah, Sonia Cerquozzi, Harold J Olney, Christina Fraga, Jill Dudebout, Anargyros Xenocostas, Nicholas Finn, Vincent Ethier, M Lynn Savoie , Lambert Busque , Kareem Jamani, Philip Kuruvilla, Carolyn Faught, Brian Leber, Rayan Kaedbey, Sarit E Assouline, Dennis Kim
    DOI 10.1016/j.leukres.2023.107374 PMID 37657146
    Consulter

  • Interplay between hereditary and acquired factors determines the neutrophil counts in older individuals

    Marie-France Gagnon , Sylvie Provost, Maxine Sun, Sami Ayachi, Manuel Buscarlet , Luigina Mollica , Natasha Szuber , Marie-Pierre Dubé , Lambert Busque
    DOI 10.1182/bloodadvances.2022008793 PMID 36930802
    Consulter

  • Somatic Mosaic Chromosomal Alterations and Death of Cardiovascular Disease Causes among Cancer Survivors

    Maxine Sun, Marie-Christyne Cyr, Johanna Sandoval, Louis-Philippe Lemieux Perreault , Lambert Busque , Jean-Claude Tardif, Marie-Pierre Dubé
    DOI 10.1158/1055-9965.EPI-22-1290 PMID 36976640
    Consulter

  • Blasts in context: the impact of the immune environment on acute myeloid leukemia prognosis and treatment

    Yasmina Serroukh , Josée Hébert , Lambert Busque , François Mercier , Chris Rudd , Sarit Assouline , Sylvie Lachance , Jean-Sébastien Delisle
    DOI 10.1016/j.blre.2022.100991 PMID 35941029
    Consulter

  • Higher Rates of Perioperative Thrombosis and Distinct Management Practices in Secondary Erythrocytosis Versus Polycythemia Vera

    Natasha Szuber , Michael Harnois, Robert Delage, Shireen Sirhan , Lambert Busque
    DOI 10.1182/blood-2022-170026
    Consulter

  • Childhood maltreatment and leukocyte telomere length in men and women with chronic illness: an evaluation of moderating and mediating influences

    Alexandra Connor, Louisia Starnino , Lambert Busque , Jean-Claude Tardif, Vincent Bourgoin, Marie-Pierre Dubé, David Busseuil, Bianca D'Antono
    DOI 10.1017/S0033291722003543 PMID 36943406
    Consulter

  • Prognostic Impact of High Calreticulin Variant Allele Frequency in Patients with Myeloproliferative Neoplasms

    Audrey Desilets, Michael Harnois , Lambert Busque , Natasha Szuber
    DOI 10.1182/blood-2022-163785
    Consulter

  • A macaque clonal hematopoiesis model demonstrates expansion of TET2-disrupted clones and utility for testing interventions

    Tae-Hoon Shin, Yifan Zhou, Shirley Chen, Stefan Cordes, Max Z. Grice, Xing Fan, Byung-Chul Lee, Aisha A. Aljanahi, So Gun Hong, Kelli L. Vaughan, Julie A. Mattison, Steven G. Kohama, Margarete A. Fabre, Naoya Uchida , Selami Demirci, Marcus A. F. Corat, Jean-Yves Métais, Katherine R. Calvo, Manuel Buscarlet, Hannah Natanson, Kathy L. McGraw, Alan F. List , Lambert Busque , John F. Tisdale, George S. Vassiliou, Kyung-Rok Yu, Cynthia E. Dunbar
    DOI 10.1182/blood.2021014875 PMID 35714307
    Consulter

  • Combined PD-L1 and TIM3 blockade improves expansion of fit human CD8+ antigen-specific T cells for adoptive immunotherapy

    Shirin Lak, Valérie Janelle, Anissa Djedid, Gabrielle Boudreau, Ann Brasey, Véronique Lisi, Ali Smaani, Cédric Carli , Lambert Busque , Vincent-Philippe Lavallée , Jean-Sébastien Delisle
    DOI 10.1016/j.omtm.2022.09.016 PMID 36320412
    Consulter

  • Perioperative management of myeloproliferative neoplasms: A pan-Canadian physician survey and international expert opinion

    Natasha Szuber , Panagiota Toliopoulos , Lambert Busque , Sonia Cerquozzi, Lynda Foltz, Vikas Gupta, Ayalew Tefferi, Alessandro Maria Vannucchi, Christopher Hillis, Brian Leber, Dawn Maze, Jaroslav Prchal, Harold J. Olney, Shireen Sirhan
    DOI 10.1002/ajh.26739 PMID 36151067
    Consulter

  • Two types of human TCR differentially regulate reactivity to self and non-self antigens

    Assya Trofimov, Philippe Brouillard, Jean-David Larouche, Jonathan Séguin, Jean-Philippe Laverdure, Ann Brasey, Gregory Ehx , Denis-Claude Roy , Lambert Busque , Sylvie Lachance , Sébastien Lemieux, Claude Perreault
    DOI 10.1016/j.isci.2022.104968 PMID 36111255
    Consulter

  • The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms

    Joseph D. Khoury, Eric Solary, Oussama Abla, Yassmine Akkari, Rita Alaggio, Jane F. Apperley, Rafael Bejar, Emilio Berti , Lambert Busque , John K. C. Chan, Weina Chen, Xueyan Chen, Wee-Joo Chng, John K. Choi, Isabel Colmenero, Sarah E. Coupland, Nicholas C. P. Cross, Daphne De Jong, M. Tarek Elghetany, Emiko Takahashi, Jean-Francois Emile, Judith Ferry, Linda Fogelstrand, Michaela Fontenay, , Ulrich Germing, Sumeet Gujral, Torsten Haferlach, Claire Harrison, Jennelle C. Hodge, Shimin Hu, Joop H. Jansen, Rashmi Kanagal-Shamanna, Hagop M. Kantarjian, Christian P. Kratz, Xiao-Qiu Li, Megan S. Lim, Keith Loeb , Sanam Loghavi, Andrea Marcogliese, Soheil Meshinchi, Phillip Michaels, Kikkeri N. Naresh, Yasodha Natkunam, Reza Nejati, German Ott, Eric Padron, Keyur P. Patel, Nikhil Patkar, Jennifer Picarsic, Uwe Platzbecker , Irene Roberts, Anna Schuh, William Sewell, Reiner Siebert, Prashant Tembhare, Jeffrey Tyner, Srdan Verstovsek, Wei Wang, Brent Wood, Wenbin Xiao, Cecilia Yeung, Andreas Hochhaus
    DOI 10.1038/s41375-022-01613-1 PMID 35732831
    Consulter

  • Natural spring water gargle samples as an alternative to nasopharyngeal swabs for SARS-CoV-2 detection using a laboratory-developed test

    Sarah Gobeille Paré, Julie Bestman-Smith, Judith Fafard, Florence Doualla-Bell, Mariève Jacob-Wagner, Christian Lavallée, Hugues Charest, Stéphanie Beauchemin, François Coutlée, Jeannot Dumaresq , Lambert Busque , Manon St-Hilaire, Guylaine Lépine, Valérie Bouche, Marc Desforges, Isabelle Goupil-Sormany, Annie-Claude Labbé; G-SPIT study group
    DOI 10.1002/jmv.27407 PMID 34672374
    Consulter

  • Acute central nervous system graft-versus-host-disease after liver transplantation

    Valérie Massey, Véronique Martel, Dang Khoa Nguyen , Lambert Busque , Hugo Chapdelaine, Mark Robert Keezer
    DOI 10.1016/j.trim.2021.101521 PMID 34952167
    Consulter

  • BCR-ABL1 transcript doubling time as a predictor for treatment-free remission failure after imatinib discontinuation in chronic myeloid leukaemia in chronic phase

    Dennis Dong Hwan Kim, Taehyung Simon Kim, Eshetu G. Atenafu, Igor Novitzky Basso, Donna Forrest, Isabelle Bence-Bruckler, Lynn Savoie , Lambert Busque , Mary-Margaret Keating, Robert Delage, Anargyros Xenocostas, Elena Liew, Kristjan Paulson, Tracy Stockley, Pierre Laneuville, Jeffrey H. Lipton, Suzanne Kamel-Reid, Brian Leber
    DOI 10.1111/bjh.17807 PMID 34496035
    Consulter

  • The safety and efficacy of dasatinib plus nivolumab in patients with previously treated chronic myeloid leukemia: results from a phase 1b dose-escalation study

    Joaquín Martínez-López, Satu Mustjoki, Kimmo Porkka, Rebecca B Klisovic, Dominik Wolf , Lambert Busque , Juan Carlos Hernández-Boluda, Rene Swanink, Patricia Martin Regueira, Jeffrey H Lipton
    DOI 10.1080/10428194.2021.1889536 PMID 33653205
    Consulter

  • Colchicine for community-treated patients with COVID-19 (COLCORONA): a phase 3, randomised, double-blinded, adaptive, placebo-controlled, multicentre trial

    Jean-Claude Tardif, Nadia Bouabdallaoui, Philippe L L'Allier, Daniel Gaudet, Binita Shah, Michael H Pillinger, Jose Lopez-Sendon, Protasio da Luz, Lucie Verret, Sylvia Audet , Jocelyn Dupuis, André Denault, Martin Pelletier, Philippe A Tessier, Sarah Samson, Denis Fortin, Jean-Daniel Tardif, David Busseuil, Elisabeth Goulet, Chantal Lacoste , Anick Dubois, Avni Y Joshi, David D Waters, Priscilla Hsue, Norman E Lepor, Frédéric Lesage, Nicolas Sainturet, Eve Roy-Clavel, Zohar Bassevitch, Andreas Orfanos, Gabriela Stamatescu, Jean C Grégoire , Lambert Busque , Christian Lavallée, Pierre-Olivier Hétu, Jean-Sébastien Paquette, Spyridon G Deftereos, Sylvie Levesque, Mariève Cossette, Anna Nozza, Malorie Chabot-Blanchet, Marie-Pierre Dubé, Marie-Claude Guertin, Guy Boivin; COLCORONA Investigators
    DOI 10.1016/S2213-2600(21)00222-8 PMID 34051877
    Consulter

  • Risk of infection in MPN patients in the era of Covid-19: A prospective multicenter study of 257 patients from the CML-MPN Quebec Research Group

    Kevin Simpson-Poirier, Michaël Harnois, Harold J Olney, Shireen Sirhan , Michel-Olivier Gratton , Sarit Assouline, Pierre Laneuville, Robert Delage , Luigina Mollica , Lambert Busque , Natasha Szuber
    DOI 10.1002/ajh.26159 PMID 33719144
    Consulter

  • Optimal duration of imatinib treatment/deep molecular response for treatment-free remission after imatinib discontinuation from a Canadian tyrosine kinase inhibitor discontinuation trial

    Dennis D. H. Kim, Igor Novitzky-Basso, Taehyung S. Kim, Eshetu G. Atenafu, Donna Forrest, Lynn Savoie, Isabelle Bence-Bruckler, Mary-Margaret Keating , Lambert Busque , Robert Delage, Anargyros Xenocostas, Elena Liew, Kristjan Paulson, Tracy Stockley, Pierre Laneuville, Jeffrey H. Lipton, Suzanne Kamel-Reid, Brian Leber
    DOI 10.1111/bjh.17447 PMID 33876423
    Consulter

  • Phenotypical differences and thrombosis rates in secondary erythrocytosis versus polycythemia vera

    Eliane Nguyen, Michaël Harnois , Lambert Busque , Shireen Sirhan, Sarit Assouline, Ines Chamaki, Harold Olney , Luigina Mollica , Natasha Szuber
    DOI 10.1038/s41408-021-00463-x PMID 33859172
    Consulter

  • UM171-Expanded Cord Blood Transplants Support Robust T Cell Reconstitution with Low Rates of Severe Infections

    Maude Dumont-Lagacé, Qi Li , Mégane Tanguay , Jalila Chagraoui, Tibila Kientega, Guillaume B Cardin, Ann Brasey, Assya Trofimov, Cédric Carli , Imran Ahmad , Nadia M Bambace , Léa Bernard , Thomas Kiss , Jean Roy , Denis-Claude Roy , Sébastien Lemieux, Claude Perreault, Francis Rodier, Simon Frédéric Dufresne , Lambert Busque , Sylvie Lachance , Guy Sauvageau , Sandra Cohen , Jean-Sébastien Delisle
    DOI 10.1016/j.bbmt.2020.09.031 PMID 33022376
    Consulter

  • The associations of hostility and defensiveness with telomere length are influenced by sex and health status

    Louisia Starnino, Gilles Dupuis , Lambert Busque , Vincent Bourgoin, Marie-Pierre Dubé, David Busseuil, Bianca D'Antono
    DOI 10.1186/s13293-020-00349-w PMID 33397445
    Consulter

  • Single UM171-expanded cord blood transplant can cure severe idiopathic aplastic anemia in absence of suitable donors

    Jean-Sébastien Claveau , Sandra Cohen , Imran Ahmad , Jean-Sébastien Delisle , Thomas Kiss , Sylvie Lachance , Guy Sauvageau , Lambert Busque , Rose-Marie Brito, Nadia Bambace , Léa Bernard , Denis-Claude Roy , Jean Roy
    DOI 10.1111/ejh.13504 PMID 32749758
    Consulter

  • Correction: Imatinib mesylate inhibits STAT5 phosphorylation in response to IL-7 and promotes T cell lymphopenia in chronic myelogenous leukemia patients

    S Thiant, M M Moutuou, P Laflamme, R Sidi Boumedine, D M Leboeuf , Lambert Busque , Jean Roy , M Guimond
    DOI 10.1038/s41408-020-00374-3 PMID 33149116
    Consulter

  • Oral cedazuridine/decitabine for MDS and CMML: a phase 2 pharmacokinetic/pharmacodynamic randomized crossover study

    Guillermo Garcia-Manero, Elizabeth A. Griffiths, David P. Steensma, Gail J. Roboz, Richard Wells, James McCloskey, II, Olatoyosi Odenike, Amy E. DeZern, Karen Yee , Lambert Busque , Casey O’Connell, Laura C. Michaelis, Joseph Brandwein, Hagop Kantarjian, Aram Oganesian, Mohammad Azab, Michael R. Savona
    DOI 10.1182/blood.2019004143 PMID 32285126
    Consulter

  • High-sensitivity C-reactive protein is associated with clonal hematopoiesis of indeterminate potential

    Lambert Busque , Maxine Sun, Manuel Buscarlet, Sami Ayachi, Yassamin Feroz Zada, Sylvie Provost, Vincent Bourgoin , Luigina Mollica , Marlies Meisel, Reinhard Hinterleitner, Bana Jabri, Marie-Pierre Dubé, Jean-Claude Tardif
    DOI 10.1182/bloodadvances.2019000770 PMID 32492156
    Consulter

  • 60 Years of clonal hematopoiesis research: From X-chromosome inactivation studies to the identification of driver mutations

    Sami Ayachi, Manuel Buscarlet , Lambert Busque
    DOI 10.1016/j.exphem.2020.01.008 PMID 32001340
    Consulter

  • Hematopoietic stem cell transplantation using single UM171-expanded cord blood: a single-arm, phase 1-2 safety and feasibility study

    Sandra Cohen , Jean Roy , Sylvie Lachance , Jean-Sébastien Delisle , Anne Marinier , Lambert Busque , Denis-Claude Roy , Imran Ahmad , Nadia M Bambace , Léa Bernard , Thomas Kiss , Philippe Bouchard, Pierre Caudrelier, Sévérine Landais, Fannie Larochelle, Jalila Chagraoui, Bernhard Lehnertz, Sophie Corneau, Elisa Tomellini, Jeroen J A van Kampen, Jan J Cornelissen, Maude Dumont-Lagacé, Mégane Tanguay, Qi Li , Sébastien Lemieux, Peter W Zandstra , Guy Sauvageau
    DOI 10.1016/S2352-3026(19)30202-9 PMID 31704264
    Consulter

  • The predictive value of intracellular imatinib levels in newly diagnosed chronic myeloid leukemia

    Christopher M. Hillis, Nicholas L. Jackson Chornenki, Isabelle Bence-Bruckler , Lambert Busque , Yvan Cote, Caroline Hamm, Wanda Hasegawa, Suzanne Kamel-Reid, Lynn Savoie, A. Robert Turner, Anargyros Xenocostas, Jeffrey H. Lipton, Brian Leber
    DOI 10.1016/j.leukres.2019.106285 PMID 31846781
    Consulter

  • Allodepleted T-cell immunotherapy after haploidentical haematopoietic stem cell transplantation without severe acute graft-versus-host disease (GVHD) in the absence of GVHD prophylaxis

    Denis-Claude Roy , Sylvie Lachance , Sandra Cohen , Jean-Sébastien Delisle , Thomas Kiss , Guy Sauvageau , Lambert Busque , Imran Ahmad , Léa Bernard , Nadia M Bambace, Radia S Boumédine, Marie-Claude Guertin, Katayoun Rezvani, Stephan Mielke, Claude Perreault , Jean Roy
    DOI 10.1111/bjh.15970 PMID 31135970
    Consulter

  • Persistence with generic imatinib for chronic myeloid leukemia: a matched cohort study

    Adi J. Klil-Drori Hui Yin Laurent Azoulay Michaël Harnois , Michel-Olivier Gratton , Lambert Busque , Sarit E Assouline, Groupe Québécois de Recherche en Leucémie Myéloïde Chronique et Néoplasies Myéloprolifératives (GQR LMC-NMP)
    DOI 10.3324/haematol.2018.211235 PMID 30630987
    Consulter

  • 3023 Mayo Clinic Patients With Myeloproliferative Neoplasms: Risk-Stratified Comparison of Survival and Outcomes Data Among Disease Subgroups

    Natasha Szuber , Mythri Mudireddy, Maura Nicolosi, Domenico Penna, Rangit R Vallapureddy, Terra L Lasho, Christy Finke, Kebede H Begna, Michelle A Elliott, C Christopher Hook, Alexandra P Wolanskyj, Mrinal M Patnaik, Curtis A Hanson , Rhett P Ketterling, Shireen Sirhan, Animesh Pardanani, Naseema Gangat , Lambert Busque , Ayalew Tefferi
    DOI 10.1016/j.mayocp.2018.08.022 PMID 30824279
    Consulter

  • Molecular monitoring of therapeutic milestones and clinical outcomes in patients with chronic myeloid leukemia

    Adi J Klil-Drori, Hui Yin, Laurent Azoulay, Alexa Del Corpo, Michaël Harnois , Michel-Olivier Gratton , Harold J Olney, Robert Delage, Pierre Laneuville , Luigina Mollica , Lambert Busque , Sarit E Assouline; Groupe Québécois de Recherche en Leucémie Myéloïde Chronique et Néoplasies Myéloprolifératives (GQR LMC-NMP)
    DOI 10.1002/cncr.31835 PMID 30423211
    Consulter

  • MBD4: guardian of the epigenetic galaxy

    Lambert Busque , Lucy A Godley
    DOI 10.1182/blood-2018-08-867044 PMID 30287469
    Consulter

  • Concise Review: Age-Related Clonal Hematopoiesis: Stem Cells Tempting the Devil

    Lambert Busque , Manuel Buscarlet , Luigina Mollica , Ross L Levine
    DOI 10.1002/stem.2845 PMID 29883022
    Consulter

  • Lineage restriction analyses in CHIP indicate myeloid bias for TET2 and multipotent stem cell origin for DNMT3A

    Manuel Buscarlet, Sylvie Provost, Yassamin Feroz Zada, Vincent Bourgoin , Luigina Mollica , Marie-Pierre Dubé , Lambert Busque
    DOI 10.1182/blood-2018-01-829937 PMID 29764839
    Consulter

  • Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host

    Marlies Meisel, Reinhard Hinterleitner, Alain Pacis, Li Chen, Zachary M. Earley, Toufic Mayassi, Joseph F. Pierre, Jordan D. Ernest, Heather J. Galipeau, Nikolaus Thuille, Romain Bouziat, Manuel Buscarlet, Daina L. Ringus , Yitang Wang, Ye Li, Vu Dinh, Sangman M. Kim, Benjamin D. McDonald, Matthew A. Zurenski, Mark W. Musch, Glaucia C. Furtado, Sergio A. Lira, Gottfried Baier, Eugene B. Chang, A. Murat Eren, Christopher R. Weber , Lambert Busque , Lucy A. Godley, Elena F. Verdú, Luis B. Barreiro, Bana Jabri
    DOI 10.1038/s41586-018-0125-z PMID 29769727
    Consulter

  • Rationale, design, and preliminary results of the Quebec Warfarin Cohort Study

    Sylvie Perreault, Payman Shahabi, Robert Côté, Stéphanie Dumas, Étienne Rouleau-Mailloux, Yassamin Feroz Zada, Sylvie Provost, Ian Mongrain, Marc Dorais, Thao Huynh, Simon Kouz, Ariel Diaz , Mark Blostein, Simon de Denus, Jacques Turgeon, Jeffrey Ginsberg, Jacques Lelorier, Lyne Lalonde , Lambert Busque , Jeannine Kassis , Mario Talajic, Jean-Claude Tardif, Marie-Pierre Dubé
    DOI 10.1002/clc.22948 PMID 29542828
    Consulter

  • Clonal Hematopoiesis and Evolution to Hematopoietic Malignancies

    Robert L Bowman , Lambert Busque , Ross L Levine
    DOI 10.1016/j.stem.2018.01.011 PMID 29395053
    Consulter

  • Identification of the genetic determinants responsible for retinal degeneration in families of Mexican descent

    Adda Villanueva, Pooja Biswas, Kameron Kishaba, John Suk, Keerti Tadimeti, Pongali B Raghavendra, Karine Nadeau , Bruno Lamontagne , Lambert Busque , Steve Geoffroy, Ian Mongrain, Géraldine Asselin, Sylvie Provost, Marie-Pierre Dubé, Eric Nudleman, Radha Ayyagari
    DOI 10.1080/13816810.2017.1373830 PMID 28945494
    Consulter

  • Clinical-Scale Rapid Autologous BK Virus-Specific T Cell Line Generation From Kidney Transplant Recipients With Active Viremia for Adoptive Immunotherapy

    Caroline Lamarche, Julie Orio, Victoria Georges-Tobar, Thomas Pincez, Mathieu Goupil, Amina Dahmani, Cedric Carli, Ann Brasey , Lambert Busque , Jean-Sébastien Delisle
    DOI 10.1097/TP.0000000000001698 PMID 28230645
    Consulter

  • Early switch to second-line tyrosine kinase inhibitor in chronic myeloid leukemia patients failing to achieve early molecular response

    Adi J. Klil-Drori, Hui Yin, Laurent Azoulay, Michaël Harnois , Michel-Olivier Gratton , Alexa Del Corpo, Harold J. Olney, Robert Delage, Pierre Laneuville , Luigina Mollica , Lambert Busque , Sarit E. Assouline, On behalf of the Quebec CML Group
    DOI 10.1002/ajh.24838 PMID 28670773
    Consulter

  • DNMT3A and TET2 dominate clonal hematopoiesis and demonstrate benign phenotypes and different genetic predispositions

    Manuel Buscarlet, Sylvie Provost, Yassamin Feroz Zada, Amina Barhdadi, Vincent Bourgoin, Guylaine Lépine , Luigina Mollica , Natasha Szuber , Marie-Pierre Dubé , Lambert Busque
    DOI 10.1182/blood-2017-04-777029 PMID 28655780
    Consulter

  • Imatinib mesylate inhibits STAT5 phosphorylation in response to IL-7 and promotes T cell lymphopenia in chronic myelogenous leukemia patients

    S Thiant, M M Moutuou, P Laflamme, R Sidi Boumedine, D M Leboeuf , Lambert Busque , Jean Roy , M Guimond
    DOI 10.1038/bcj.2017.29 PMID 28387753
    Consulter

  • HSPCs are marathon and not sprint relay athletes

    Lambert Busque
    DOI 10.1182/blood-2017-02-763516 PMID 28302687
    Consulter

  • Human blood cell levels of 5-hydroxymethylcytosine (5hmC) decline with age, partly related to acquired mutations in TET2

    Manuel Buscarlet, Alain Tessier, Sylvie Provost , Luigina Mollica , Lambert Busque
    DOI 10.1016/j.exphem.2016.07.009 PMID 27475703
    Consulter

  • Psychological Profiles in the Prediction of Leukocyte Telomere Length in Healthy Individuals

    Louisia Starnino , Lambert Busque , Jean-Claude Tardif, Bianca D'Antono
    DOI 10.1371/journal.pone.0165482 PMID 27788238
    Consulter

  • Laboratory Investigation of Myeloproliferative Neoplasms (MPNs): Recommendations of the Canadian Mpn Group

    Lambert Busque , Anna Porwit, Radmila Day, Harold J Olney, Brian Leber, Vincent Éthier, Shireen Sirhan, Linda Foltz, Jaroslav Prchal, Suzanne Kamel-Reid, Aly Karsan, Vikas Gupta
    DOI 10.1093/ajcp/aqw131 PMID 27686169
    Consulter

  • Novel germline mutations in the calreticulin gene: implications for the diagnosis of myeloproliferative neoplasms

    Natasha Szuber , Bruno Lamontagne , Lambert Busque
    DOI 10.1136/jclinpath-2016-203940 PMID 27466382
    Consulter

  • Evaluating the Impact of a Switch to Nilotinib on Imatinib-Related Chronic Low-Grade Adverse Events in Patients With CML-CP: The ENRICH Study

    Jorge E Cortes, Jeffrey H Lipton, Carole B Miller , Lambert Busque , Luke P Akard, Javier Pinilla-Ibarz, Christopher Keir, Ghulam Warsi, Felice P Lin, Michael J Mauro
    DOI 10.1016/j.clml.2016.02.002 PMID 26993758
    Consulter

  • Favorable long-term outcome of patients with multiple myeloma using a frontline tandem approach with autologous and non-myeloablative allogeneic transplantation

    Imran Ahmad , Richard LeBlanc , Sandra Cohen , Sylvie Lachance , Thomas Kiss , Guy Sauvageau , Denis-Claude Roy , Lambert Busque , Jean-Sébastien Delisle , Nadia M Bambace , Léa Bernard , W Sabry , Jean Roy
    DOI 10.1038/bmt.2015.319 PMID 26691426
    Consulter

  • Evolving Therapeutic Options for Polycythemia Vera: Perspectives of the Canadian Myeloproliferative Neoplasms Group

    Shireen Sirhan , Lambert Busque , Lynda Foltz, Kuljit Grewal, Caroline Hamm, Nicole Laferriere, Pierre Laneuville, Brian Leber, Elena Liew, Harold J Olney, Jaroslav Prchal, Anna Porwit, Vikas Gupta
    DOI 10.1016/j.clml.2015.07.650 PMID 26433906
    Consulter

  • Integrated genomic analysis illustrates the central role of JAK-STAT pathway activation in myeloproliferative neoplasm pathogenesis

    Raajit Rampal, Fatima Al-Shahrour, Omar Abdel-Wahab, Jay P. Patel, Jean-Philippe Brunel, Craig H. Mermel, Adam J. Bass, Jennifer Pretz, Jihae Ahn, Todd Hricik, Outi Kilpivaara, Martha Wadleigh , Lambert Busque , D. Gary Gilliland, Todd R. Golub, Benjamin L. Ebert, Ross L. Levine
    DOI 10.1182/blood-2014-02-554634 PMID 24740812
    Consulter

  • Safety and cost-effectiveness of outpatient autologous stem cell transplantation in patients with multiple myeloma

    Andreas Holbro , Imran Ahmad , Sandra Cohen , Jean Roy , Sylvie Lachance , Miguel Chagnon , Richard LeBlanc , Léa Bernard , Lambert Busque , Denis-Claude Roy , Guy Sauvageau , Thomas Kiss
    DOI 10.1016/j.bbmt.2012.12.006 PMID 23253556
    Consulter

  • Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis

    Lambert Busque , Jay P Patel, Maria E Figueroa, Aparna Vasanthakumar, Sylvie Provost, Zineb Hamilou , Luigina Mollica , Juan Li, Agnes Viale, Adriana Heguy, Maryam Hassimi, Nicholas Socci, Parva K Bhatt, Mithat Gonen, Christopher E Mason, Ari Melnick, Lucy A Godley, Cameron W Brennan, Omar Abdel-Wahab, Ross L Levine
    DOI 10.1038/ng.2413 PMID 23001125
    Consulter

  • Tandem autologous-allogeneic nonmyeloablative sibling transplantation in relapsed follicular lymphoma leads to impressive progression-free survival with minimal toxicity

    Sandra Cohen , Thomas Kiss , Sylvie Lachance , Denis-Claude Roy , Guy Sauvageau , Lambert Busque , Imran Ahmad , Jean Roy
    DOI 10.1016/j.bbmt.2011.11.028 PMID 22155507
    Consulter

  • Cardiac tamponade potentially related to sirolimus following cord blood transplantation

    A Holbro , Imran Ahmad , Lambert Busque , Sandra Cohen , Sylvie Lachance , Denis-Claude Roy , Jean Roy , Guy Sauvageau , Thomas Kiss
    DOI 10.1038/bmt.2011.44 PMID 21399672
    Consulter

  • Emerging therapeutic options for myelofibrosis: a Canadian perspective

    Vikas Gupta, Lynda Foltz, Shireen Sirhan , Lambert Busque , A Robert Turner
    PMID 23119228
    Consulter

  • Incidence and prognostic value of eosinophilia in chronic graft-versus-host disease after nonmyeloablative hematopoietic cell transplantation

    Imran Ahmad , Annie-Claude Labbé, Miguel Chagnon , Lambert Busque , Sandra Cohen , Thomas Kiss , Sylvie Lachance , Denis-Claude Roy , Guy Sauvageau , Jean Roy
    DOI 10.1016/j.bbmt.2011.04.012 PMID 21601640
    Consulter

  • The replication rate of human hematopoietic stem cells in vivo

    Sandra N Catlin , Lambert Busque , Rosemary E Gale, Peter Guttorp, Janis L Abkowitz
    DOI 10.1182/blood-2010-08-303537 PMID 21343613
    Consulter

  • The most commonly reported variant in ASXL1 (c.1934dupG;p.Gly646TrpfsX12) is not a somatic alteration

    O Abdel-Wahab, O Kilpivaara, J Patel , Lambert Busque , R L Levine
    DOI 10.1038/leu.2010.144 PMID 20596031
    Consulter

  • Late acute renal failure due to bilateral kidney infiltration by ALL as single manifestation of relapse after allogeneic transplantation

    M Detrait, C Meunier , Denis-Claude Roy , Thomas Kiss , Sylvie Lachance , Sandra Cohen , Lambert Busque , Guy Sauvageau , Jean Roy
    DOI 10.1038/bmt.2009.246 PMID 19767785
    Consulter

  • No association between telomere length and blood cell counts in elderly individuals

    Luigina Mollica , Isabelle Fleury , Claude Belisle, Sylvie Provost , Denis-Claude Roy , Lambert Busque
    DOI 10.1093/gerona/glp065 PMID 19435952
    Consulter

  • Graft-versus-host disease prophylaxis with tacrolimus and mycophenolate mofetil in HLA-matched nonmyeloablative transplant recipients is associated with very low incidence of GVHD and nonrelapse mortality

    Waleed Sabry , Richard LeBlanc , Annie-Claude Labbé , Guy Sauvageau , Stephen Couban , Thomas Kiss , Lambert Busque , Sandra Cohen , Sylvie Lachance , Denis-Claude Roy , Jean Roy
    DOI 10.1016/j.bbmt.2009.04.004 PMID 19589481
    Consulter

  • Diphyllobothriasis, a rare cause of profuse diarrhea following autologous transplantation

    M Detrait, L Poirier , Denis-Claude Roy , Thomas Kiss , Lambert Busque , Sandra Cohen , Sylvie Lachance , Guy Sauvageau , Jean Roy
    DOI 10.1038/bmt.2008.439 PMID 19169286
    Consulter

  • Skewing of X-inactivation ratios in blood cells of aging women is confirmed by independent methodologies

    Lambert Busque , Yves Paquette, Sylvie Provost , Denis-Claude Roy , Ross L Levine , Luigina Mollica , D Gary Gilliland
    DOI 10.1182/blood-2008-12-195677 PMID 19202126
    Consulter

  • Differential expression of SMAD3 transcripts is not regulated by cis-acting genetic elements but has a gender specificity

    Lambert Busque , C Belisle, S Provost , Martin Giroux , C Perreault
    DOI 10.1038/gene.2008.101 PMID 19129849
    Consulter

  • Telomere length is severely and similarly reduced in JAK2V617F-positive and -negative myeloproliferative neoplasms

    Léa Bernard , C Belisle , Luigina Mollica , S Provost , Denis-Claude Roy , D G Gilliland, R L Levine , Lambert Busque
    DOI 10.1038/leu.2008.319 PMID 19005480
    Consulter

  • Non-traumatic necrosis of bone (osteonecrosis) is associated with endothelial cell activation but not thrombophilia

    C Séguin , Jeannine Kassis , Lambert Busque , A Bestawros, J Theodoropoulos, M-L Alonso, E J Harvey
    DOI 10.1093/rheumatology/ken206 PMID 18524806
    Consulter

  • Evidence suggesting the presence of a stem cell clone anteceding the acquisition of the JAK2-V617F mutation

    R Jamal, C Bélisle, M-C Lessard , Josée Hébert , Denis-Claude Roy , R Levine , Lambert Busque
    DOI 10.1038/leu.2008.6 PMID 18239619
    Consulter

  • Hb Montreal II: a novel elongated beta-globin variant caused by a frameshift mutation [beta142 (-C)]

    Pierre Chagnon , Luigina Mollica , Claude Belisle, Céline Deveaux, Giovanni D Angelo , Denis-Claude Roy , Denis Soulières , Lambert Busque
    DOI 10.1080/03630260802173593 PMID 18654885
    Consulter

  • No evidence that skewing of X chromosome inactivation patterns is transmitted to offspring in humans

    Véronique Bolduc, Pierre Chagnon, Sylvie Provost, Marie-Pierre Dubé, Claude Belisle, Marianne Gingras , Luigina Mollica , Lambert Busque
    DOI 10.1172/JCI33166 PMID 18097474
    Consulter

  • High incidence of invasive aspergillosis associated with intestinal graft-versus-host disease following nonmyeloablative transplantation

    Annie-Claude Labbé, Shi Hann Su, Michel Laverdière, Jacques Pépin, Carlos Patiño , Sandra Cohen , Thomas Kiss , Sylvie Lachance , Guy Sauvageau , Lambert Busque , Denis-Claude Roy , Jean Roy
    DOI 10.1016/j.bbmt.2007.06.013 PMID 17889356
    Consulter

  • Endothelial-like vascular progenitor cells (VPCs) from allogeneic and autologous donors: mobilization features distinct from hematopoietic progenitors

    David S Allan, Pascale Dubé , Jean Roy , Lambert Busque , Denis-Claude Roy
    DOI 10.1016/j.bbmt.2006.11.016 PMID 17382249
    Consulter

  • Prediction of graft-versus-host disease in humans by donor gene-expression profiling

    Chantal Baron, Roland Somogyi, Larry D Greller, Vincent Rineau, Peter Wilkinson, Carolyn R Cho, Mark J Cameron, David J Kelvin, Pierre Chagnon , Denis-Claude Roy , Lambert Busque , Rafick-Pierre Sékaly, Claude Perreault
    DOI 10.1371/journal.pmed.0040023 PMID 17378698
    Consulter

  • X-inactivation-based clonality analysis and quantitative JAK2V617F assessment reveal a strong association between clonality and JAK2V617F in PV but not ET/MMM, and identifies a subset of JAK2V617F-negative ET and MMM patients with clonal hematopoiesis

    Ross L Levine, Claude Belisle, Martha Wadleigh, David Zahrieh, Stephanie Lee, Pierre Chagnon, D Gary Gilliland , Lambert Busque
    DOI 10.1182/blood-2005-09-3900 PMID 16434490
    Consulter

  • Identification and characterization of an Xp22.33;Yp11.2 translocation causing a triplication of several genes of the pseudoautosomal region 1 in an XX male patient with severe systemic lupus erythematosus

    Pierre Chagnon, Rayfel Schneider, Josée Hébert, Paul R Fortin, Sylvie Provost, Claude Belisle, Marianne Gingras, Véronique Bolduc, Claude Perreault, Earl Silverman , Lambert Busque
    DOI 10.1002/art.21733 PMID 16575839
    Consulter

  • Evidence that donor intrinsic response to G-CSF is the best predictor of acute graft-vs-host disease following allogeneic peripheral blood stem cell transplantation

    Nathalie Dhédin, Inès Chamakhi, Claude Perreault , Denis-Claude Roy , Guy Sauvageau , Thierry Ducruet , Lambert Busque , Douglas Fish, Robert Bélanger , Jean Roy
    DOI 10.1016/j.exphem.2005.09.013 PMID 16413397
    Consulter

  • Age-associated skewing of X-inactivation ratios of blood cells in normal females: a candidate-gene analysis approach

    Pierre Chagnon, Sylvie Provost, Claude Belisle, Véronique Bolduc, Marianne Gingras , Lambert Busque
    DOI 10.1016/j.exphem.2005.06.023 PMID 16219543
    Consulter

  • Maintaining high autopsy rates in a Canadian blood and marrow transplant program: preserving a diagnostic and research tool

    D S Allan, R Bélanger , Lambert Busque , Sandra Cohen , D Fish , Denis-Claude Roy , Jean Roy
    DOI 10.1038/sj.bmt.1704869 PMID 15735662
    Consulter

  • Antiphospholipid antibodies and thrombosis: association with acquired activated protein C resistance in venous thrombosis and with hyperhomocysteinemia in arterial thrombosis

    Jeannine Kassis , Carolyn Neville, Joyce Rauch , Lambert Busque , Erika R Chang, Lawrence Joseph, Martine Le Comte, Rebecca Subang, Paul R Fortin
    DOI 10.1160/TH04-03-0138 PMID 15583739
    Consulter

  • Acute leukemia of donor origin arising after stem cell transplantation for acute promyelocytic leukemia

    Andrew S Daly, Suzanne Kamel-Reid, Jeffrey H Lipton, Hans A Messner , Thomas Kiss , Kathy Chun , Lambert Busque , Hong Chang
    DOI 10.1016/j.leukres.2004.02.003 PMID 15289025
    Consulter

  • The presence of multiple prothrombotic risk factors is associated with a higher risk of thrombosis in individuals with anticardiolipin antibodies

    Marie Hudson, Andrée-Laure Herr, Joyce Rauch, Carolyn Neville, Erika Chang, Reda Ibrahim, Chantal Séguin , Jeannine Kassis , Lambert Busque , Paul R Fortin
    PMID 14677182
    Consulter

  • Unrelated bone marrow transplantation for leukocyte adhesion deficiency

    N J Farinha, M Duval, E Wagner, J Champagne, N Lapointe, S Barrette, B Tapiero , Lambert Busque , M A Champagne
    DOI 10.1038/sj.bmt.1703719 PMID 12476295
    Consulter

  • Development and evaluation of a PCR method for detection of the Clostridium difficile toxin B gene in stool specimens

    C Guilbault, A-C Labbé, L Poirier , Lambert Busque , C Béliveau, M Laverdière
    DOI 10.1128/JCM.40.6.2288-2290.2002 PMID 12037113
    Consulter

  • Allogeneic transplantation for multiple myeloma: further evidence for a GVHD-associated graft-versus-myeloma effect

    Richard LeBlanc , S Montminy-Métivier, R Bélanger , Lambert Busque , D Fish , Denis-Claude Roy , Jeannine Kassis , J Boileau, R Lavallée, D Bélanger, F Letendre , Josée Hébert , Guy Sauvageau , C Perreault , Jean Roy
    DOI 10.1038/sj.bmt.1703253 PMID 11781644
    Consulter

  • Hyperhomocysteinemia in hemodialysis patients: effects of 12-month supplementation with hydrosoluble vitamins

    R Tremblay, A Bonnardeaux, D Geadah , Lambert Busque , M Lebrun, D Ouimet, M Leblanc
    DOI 10.1046/j.1523-1755.2000.00234.x PMID 10916110
    Consulter

  • Relapse after bone marrow transplantation: evidence for distinct immunological mechanisms between adult and paediatric populations

    M Guimond , Lambert Busque , C Baron, Y Bonny, R Bélanger, J Mattioli, C Perreault , Denis-Claude Roy
    DOI 10.1046/j.1365-2141.2000.01961.x PMID 10848792
    Consulter

  • Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

    W J Song, M G Sullivan, R D Legare, S Hutchings, X Tan, D Kufrin, J Ratajczak, I C Resende, C Haworth, R Hock, M Loh, C Felix , Denis-Claude Roy , Lambert Busque , D Kurnit, C Willman, A M Gewirtz, N A Speck, J H Bushweller, F P Li, K Gardiner, M Poncz, J M Maris, D G Gilliland
    DOI 10.1038/13793 PMID 10508512
    Consulter

  • Development of a highly polymorphic STR marker for identity testing purposes at the human androgen receptor gene (HUMARA)

    D Desmarais, Y Zhong, R Chakraborty, C Perreault , Lambert Busque
    PMID 9729823
    Consulter

  • Quantitative assessment of hematopoietic chimerism after allogeneic bone marrow transplantation has predictive value for the occurrence of irreversible graft failure and graft-vs.-host disease

    M Gyger, C Baron, L Forest, P Lussier, F Lagacé, I Bissonnette, R Bélanger, Y Bonny , Lambert Busque , Denis-Claude Roy , C Perreault
    PMID 9590660
    Consulter

  • X-inactivation analysis in the 1990s: promise and potential problems

    Lambert Busque , D G Gilliland
    DOI 10.1038/sj.leu.2400936 PMID 9519772
    Consulter

  • Lymphoma cell burden in progenitor cell grafts measured by competitive polymerase chain reaction: less than one log difference between bone marrow and peripheral blood sources

    B M Léonard, F Hétu , Lambert Busque , M Gyger, R Bélanger, C Perreault , Denis-Claude Roy
    PMID 9414302
    Consulter

  • Analysis of allele distribution for six short tandem repeat loci in the French Canadian population of Québec

    Lambert Busque , D Desmarais, S Provost, J W Schumm, Y Zhong, R Chakraborty
    PMID 9397560
    Consulter

  • Familial antiphospholipid syndrome and HLA-DRB gene associations

    N Hudson , Lambert Busque , J Rauch , Jeannine Kassis , P R Fortin
    DOI 10.1002/art.1780401030 PMID 9336432
    Consulter

  • Demonstration of an osteoblast defect in two cases of human malignant osteopetrosis. Correction of the phenotype after bone marrow transplant

    D Lajeunesse , Lambert Busque , P Ménard, M G Brunette, Y Bonny
    DOI 10.1172/JCI118984 PMID 8878435
    Consulter

  • Nonrandom X-inactivation patterns in normal females: lyonization ratios vary with age

    Lambert Busque , R Mio, J Mattioli, E Brais, N Blais, Y Lalonde, M Maragh, D G Gilliland
    PMID 8704202
    Consulter

  • Sequential analysis of early hematopoietic reconstitution following allogeneic bone marrow transplantation with fluorescence in situ hybridization (FISH)

    C Lapointe, L Forest, P Lussier , Lambert Busque , F Lagace, C Perreault , Denis-Claude Roy , M Gyger
    PMID 8807127
    Consulter

  • The PGK-PCR clonality assay (PPCA)

    Lambert Busque , D G Gilliland
    DOI 10.1007/BF02900366 PMID 8837034
    Consulter

  • Analysis of meningiomas by methylation- and transcription-based clonality assays

    J Zhu, M P Frosch , Lambert Busque , A H Beggs, K Dashner, D G Gilliland, P M Black
    PMID 7641206
    Consulter

  • Natural killer cell lymphoproliferative disease associated with neuropathy

    D Leitenberg, R N Eisen, J M Goldstein , Lambert Busque , H M Rinder, P Stys, M E Katz, D G Gilliland, B R Smith
    DOI 10.1016/s0002-9343(99)80112-0 PMID 7598151
    Consulter

  • Clonality in juvenile chronic myelogenous leukemia

    Lambert Busque , D G Gilliland, J T Prchal, C A Sieff, H J Weinstein, J M Sokol, M Belickova, A S Wayne, K S Zuckerman, L Sokol, et al.
    PMID 7803795
    Consulter

  • Langerhans'-cell histiocytosis (histiocytosis X)--a clonal proliferative disease

    C L Willman , Lambert Busque , B B Griffith, B E Favara, K L McClain, M H Duncan, D G Gilliland
    DOI 10.1056/NEJM199407213310303 PMID 8008029
    Consulter

  • Human pituitary adenomas show no loss of heterozygosity at the retinoblastoma gene locus

    J Zhu, S P Leon, A H Beggs , Lambert Busque , D G Gilliland, P M Black
    DOI 10.1210/jcem.78.4.8157722 PMID 8157722
    Consulter

  • An expression based clonality assay at the human androgen receptor locus (HUMARA) on chromosome X

    Lambert Busque , J Zhu, D DeHart, B Griffith, C Willman, R Carroll, P M Black, D G Gilliland
    DOI 10.1093/nar/22.4.697 PMID 8127721
    Consulter

  • Clonality analysis of childhood ALL in remission: no evidence of clonal hematopoiesis

    Lambert Busque , R Ilaria Jr, R Tantravahi, H Weinstein, D G Gilliland
    DOI 10.1016/0145-2126(94)90121-x PMID 8107490
    Consulter

  • Clonal evolution in acute myeloid leukemia

    Lambert Busque , D G Gilliland
    PMID 8329693
    Consulter

  • Cytogenic characterization of primary refractory anemia

    M Gyger, G D'Angelo, R Bélanger, L Forest, P Lussier , Lambert Busque , C Perreault, J Boileau, Y Bonny, R Lavallée, et al.
    DOI 10.1002/ajh.2830410404 PMID 1288285
    Consulter

  • Alloimmunization to platelet antigen HPA-1a (PIA1) is strongly associated with both HLA-DRB3*0101 and HLA-DQB1*0201

    D L'Abbé, L Tremblay, M Filion , Lambert Busque , M Goldman, F Décary, P Chartrand
    DOI 10.1016/0198-8859(92)90036-m PMID 1358865
    Consulter