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Centre intégré universitaire de santé
et de services sociaux de l'Est-de-l'Île-de-Montréal

Centre intégré universitaire de santé et de services sociaux de l'Est-de-l'Île-de-Montréal

    Caroline Lamarche, M.D., M. Sc.

    Caroline Lamarche

    Néphrologue, Professeure agrégée de clinique

    L'équipe de l’IHOT

    Chercheur-clinicien

    Contact

    Tél. : 514 252-3404

    Dre Caroline Lamarche a obtenu une maîtrise en sciences biomédicales de l’Université de Montréal en plus de sa formation médicale en néphrologie. Ses champs d’expertise vont de la recherche fondamentale en immunologie jusqu’aux études cliniques d’immunothérapie et de thérapie cellulaire. 

    • Membre du comité de vulgarisation scientifique du Centre de recherche HMR : 2022-2026 
    • Membre du comité opérationnel recherche de l'IHOT : 2025-présent
    • Directrice de l'unité d'immunothérapie de l'axe de néphrologie du Centre de recherche HMR
    • Chercheuse-boursière clinicienne Junior 1 du FRQS : 2022-2026
    • Entrée en poste à l’Hôpital Maisonneuve-Rosemont : 2020

    Formations

    • Fellowship en immunologie - 2016-2020

      Université de Colombie-Britannique (Canada)

    • Maîtrise en sciences biomédicales - 2014-2017

      Université de Montréal (Canada)

    • Résidences en médecine interne et néphrologie - 2010-2015

      Université de Montréal (Canada)

    • Doctorat en médecine - 2006-2010

      Université de Sherbrooke (Canada)

    Découvrez ses publications

    • Highlights of 2024: Tregs immunometabolism and how to counter inflammatory niches

      Nicolas Valentini, Christopher J Requejo Cier , Caroline Lamarche
      DOI 10.1111/imcb.70027 PMID 40320285
      Consulter

    • Efficacy and Safety of Ravulizumab in IgA Nephropathy: A Phase 2 Randomized Double-Blind Placebo-Controlled Trial

      Richard Lafayette, James Tumlin, Roberta Fenoglio, Jessica Kaufeld, Miguel Ángel Pérez Valdivia, Mai-Szu Wu, Shih-Han Susan Huang, Eric Alamartine , Sung Gyun Kim, Min Yee, Andreas Kateifides, Kara Rice, Katherine Garlo, Jonathan Barratt; SANCTUARY Study Investigators , Caroline Lamarche
      DOI 10.1681/ASN.0000000534 PMID 39455063
      Consulter

    • Assessment of renal perfusion with 82-rubidium PET in patients with normal and abnormal renal function

      Alexandre Bibeau-Delisle, Nadia Bouabdallaoui , Caroline Lamarche , Francois Harel, Matthieu Pelletier-Galarneau
      DOI 10.1097/MNM.0000000000001890 PMID 39155795
      Consulter

    • Impact of Prolonged SARS-CoV-2 Dosing Interval in Hemodialysis Patients

      Caroline Lamarche , Karthik Tennankore, Lorie Marchitto, William Beabien-Souligny, Rémi Goupil, Annie-Claire Nadeau-Fredette, Lakshman Gunaratnam, Fabrice Mac-Way , Mehdi Benlarbi, Debashree Chatterjee, Alexander Tom, Halima Medjahed, Daniel E Kaufmann, Andrés Finzi, Rita S Suri; Réseau Néphrologique Québécois (Quebec Renal Network) COVID-19 Study Investigators
      DOI 10.1016/j.ekir.2024.04.072 PMID 39156179
      Consulter

    • Calcineurin Inhibitor in NEuRoloGically deceased donors to decrease kidney delayed graft function study: study protocol of the CINERGY Pilot randomised controlled trial

      Frederick D'Aragon, Markus Selzner, Ruth Breau, Marie-Hélène Masse, Francois Lamontagne, Mélanie Masse, Michael Chassé, François-Martin Carrier , Héloïse Cardinal, Prosanto Chaudhury, Matthew Weiss, Francois Lauzier, Alexis F Turgeon, Anne-Julie Frenette, Brigitte Bolduc, Anique Ducharme , Caroline Lamarche , Etienne Couture, Sandra Holdsworth, Liz Bertholz, Heather Talbot, Marat Slessarev, Patrick Luke, John Gordon Boyd, M Khaled Shamseddin, Karen E A Burns, Jeffrey Zaltzman, Shane English , Greg Knoll, Sonny Dhanani, Andrew Healey, Steven Hanna, Bram Rochwerg, Simon J W Oczkowski, Darin Treleaven, Maureen Meade; Canadian Critical Care Trials Group and the Canadian Donation and Transplant Research Program
      DOI 10.1136/bmjopen-2024-086777 PMID 38871657
      Consulter

    • Identification of inflammatory biomarkers in IgA nephropathy using the NanoString technology: a validation study in Caucasians

      Laurence Gaumond , Caroline Lamarche , Stéphanie Beauchemin, Nathalie Henley, Naoual Elftouh, Casimiro Gerarduzzi, Louis-Philippe Laurin
      DOI 10.1007/s00011-023-01848-3 PMID 38291238
      Consulter

    • Cardiovascular Risk in Patients With Glomerular Disease: A Narrative Review of the Epidemiology, Mechanisms, Management, and Patient Priorities

      Robert L Myette , Caroline Lamarche , Ayodele Odutayo, Nancy Verdin, Mark Canney
      DOI 10.1177/20543581241232472 PMID 38404647
      Consulter

    • Unlocking the potential of Tregs: innovations in CAR technology

      Christopher J Requejo Cier, Nicolas Valentini , Caroline Lamarche
      DOI 10.3389/fmolb.2023.1267762 PMID 37900916
      Consulter

    • Regulatory T-cell dysfunction and its implication for cell therapy

      Nicolas Valentini, Christopher J Requejo Cier , Caroline Lamarche
      DOI 10.1093/cei/uxad051 PMID 37158407
      Consulter

    • Kidney Biopsy Findings Among Allogenic Hematopoietic Stem Cell Transplant Recipients With Kidney Injury: A Case Series

      Guillaume Roy, Ilinca Iordachescu, Virginie Royal , Caroline Lamarche , Imran Ahmad , Annie-Claire Nadeau-Fredette, Louis-Philippe Laurin
      DOI 10.1016/j.xkme.2023.100674 PMID 37492111
      Consulter

    • Prevalence and Impact of BK Polyomavirus in the Ureters of Kidney Donors: Research Letter

      Chagnon Sarah-Jane, Yangfan Zhao, Lamontagne Bruno, Royal Virginie , Caroline Lamarche
      DOI 10.1177/20543581231166478 PMID 37065966
      Consulter

    • Tonic-signaling chimeric antigen receptors drive human regulatory T cell exhaustion

      Caroline Lamarche , Kirsten Ward-Hartstonge, Tian Mi, David T S Lin, Qing Huang, Andrew Brown, Karlie Edwards, Gherman E Novakovsky, Christopher N Qi, Michael S Kobor, Caitlin C Zebley, Evan W Weber, Crystal L Mackall, Megan K Levings
      DOI 10.1073/pnas.2219086120 PMID 36972454
      Consulter

    • A third SARS-CoV-2 mRNA vaccine dose in people receiving hemodialysis overcomes B cell defects but elicits a skewed CD4+ T cell profile

      Gérémy Sannier, Alexandre Nicolas, Mathieu Dubé, Lorie Marchitto, Manon Nayrac, Olivier Tastet, Debashree Chatterjee, Alexandra Tauzin, Raphaël Lima-Barbosa , Mélanie Laporte, Rose Cloutier, Alina M Sreng Flores, Marianne Boutin, Shang Yu Gong, Mehdi Benlarbi, Shilei Ding, Catherine Bourassa, Gabrielle Gendron-Lepage, Halima Medjahed, Guillaume Goyette, Nathalie Brassard, Gloria-Gabrielle Delgado , Julia Niessl, Laurie Gokool, Chantal Morrisseau, Pascale Arlotto, Norka Rios, Cécile Tremblay, Valérie Martel-Laferrière, Alexandre Prat, Justin Bélair, William Beaubien-Souligny, Rémi Goupil, Annie-Claire Nadeau-Fredette , Caroline Lamarche , Andrés Finzi, Rita S Suri, Daniel E Kaufmann
      DOI 10.1016/j.xcrm.2023.100955 PMID 36863335
      Consulter

    • Advancing Discovery Research in Nephrology in Canada: A Conference Report From the 2021 Molecules and Mechanisms Mediating Kidney Health and Disease (M3K) Scientific Meeting and Investigator Summit

      Dylan Burger, Amira Abdelrasoul, R Todd Alexander, Barbara Ballermann, Darren Bridgewater, John S D Chan, Joanna Cunanan, Andrey V Cybulsky , Casimiro Gerarduzzi, Lakshman Gunaratnam, Sunny Hartwig, Andras Kapus, Christopher R J Kennedy , Caroline Lamarche , Robert L Myette, Ifeanyi Kennedy Nmecha, Leanne Stalker, Katalin Szaszi, Elena Torban, Shao Ling Zhang, Tomoko Takano
      DOI 10.1177/20543581221144824 PMID 36545249
      Consulter

    • Severity of COVID-19 among solid organ transplant recipients in Canada, 2020-2021: a prospective, multicentre cohort study

      Victoria G Hall, Javier T Solera, Ghadeer Al-Alahmadi, Tina Marinelli, Heloise Cardinal, Charles Poirier, Geneviève Huard, G V Ramesh Prasad, Sacha A De Serres, Debra Isaac, Rahul Mainra , Caroline Lamarche , Ruth Sapir-Pichhadze, Susan Gilmour, Atul Humar, Deepali Kumar
      DOI 10.1503/cmaj.220620 PMID 36302101
      Consulter

    • Innate Immunity and SARS-CoV-2 Vaccine Response in Hemodialysis Patients

      Nicolas Valentini, Lorie Marchitto, Maxime Raymond, Guillaume Goyette, Daniel E Kaufmann, Andrés Finzi, Rita S Suri , Caroline Lamarche
      DOI 10.34067/KID.0002542022 PMID 36514720
      Consulter

    • Outcomes of SARS-CoV-2 Infection in Unvaccinated Compared With Vaccinated Solid Organ Transplant Recipients: A Propensity Matched Cohort Study

      Victoria G Hall, Ghadeer Al-Alahmadi, Javier T Solera, Tina Marinelli, Heloise Cardinal, G V Ramesh Prasad, Sacha A De Serres, Debra Isaac, Rahul Mainra , Caroline Lamarche , Ruth Sapir-Pichhadze, Susan Gilmour, John Matelski, Atul Humar, Deepali Kumar
      DOI 10.1097/TP.0000000000004178 PMID 35502801
      Consulter

    • Fluid Collection after Kidney Transplantation

      Ariane Deneault-Marchand, Christian Cohade , Caroline Lamarche
      DOI 10.34067/KID.0001762022 PMID 35919536
      Consulter

    • Chimeric Antigen Receptor Regulatory T Cell in Transplantation: The Future of Cell Therapy?

      Caroline Lamarche , Jonathan S Maltzman
      DOI 10.1016/j.ekir.2022.04.003 PMID 35694556
      Consulter

    • Cellular therapies in kidney transplantation

      Simon Leclerc , Caroline Lamarche
      DOI 10.1097/MNH.0000000000000737 PMID 34412086
      Consulter

    • Qualitative and Quantitative Dosage of the Anti M-Type Phospholipase A2 Receptor Autoantibody: One-Year Experience in Quebec's Reference Center

      Simon Leclerc, Karim Benkirane, Annie-Claire Nadeau-Fredette, Naoual Elftouh, Jean-Philippe Lafrance, Vincent Pichette, Virginie Royal , Caroline Lamarche , Louis-Philippe Laurin
      DOI 10.1177/20543581211052729 PMID 34721885
      Consulter

    • Minimal Change Disease With Severe Acute Kidney Injury Following the Oxford-AstraZeneca COVID-19 Vaccine: A Case Report

      Simon Leclerc, Virginie Royal , Caroline Lamarche , Louis-Philippe Laurin
      DOI 10.1053/j.ajkd.2021.06.008 PMID 34242687
      Consulter

    • Short-term antibody response after 1 dose of BNT162b2 vaccine in patients receiving hemodialysis

      Rémi Goupil, Mehdi Benlarbi, William Beaubien-Souligny, Annie-Claire Nadeau-Fredette, Debashree Chatterjee, Guillaume Goyette, Lakshman Gunaratnam , Caroline Lamarche , Alexander Tom, Andrés Finzi, Rita S Suri; Réseau Rénal Québécois (Quebec Renal Network) COVID-19 Study Investigators
      DOI 10.1503/cmaj.210673 PMID 33980499
      Consulter

    • Biomarker implementation: Evaluation of the decision-making impact of CXCL10 testing in a pediatric cohort

      Caroline Lamarche , Atul K Sharma, Aviva Goldberg, Li Wang, Tom D Blydt-Hansen
      DOI 10.1111/petr.13908 PMID 33155737
      Consulter

    • The ONE Study: One Small Step for Patient Care, a Giant Leap for Cell Therapy

      Caroline Lamarche , Jonathan S Maltzman
      DOI 10.1053/j.ajkd.2020.07.006 PMID 32763258
      Consulter

    • Donor-specific chimeric antigen receptor Tregs limit rejection in naive but not sensitized allograft recipients

      Antoine Sicard , Caroline Lamarche , Madeleine Speck, May Wong, Isaac Rosado-Sánchez, Mathilde Blois, Nicolas Glaichenhaus, Majid Mojibian, Megan K Levings
      DOI 10.1111/ajt.15787 PMID 31957209
      Consulter

    • Pharmacodynamics of 250 mg and 500 mg oral furosemide in peritoneal dialysis

      Simon Leclerc, Louis-Philippe Laurin, Jean-Philippe Lafrance , Caroline Lamarche , Denis Ouimet, François Paquette, Vincent Pichette, Annie-Claire Nadeau-Fredette
      DOI 10.5414/CP203594 PMID 31657712
      Consulter

    • TGFβ Programs Central Memory Differentiation in Ex Vivo-Stimulated Human T Cells

      Amina Dahmani, Valérie Janelle, Cédric Carli, Manon Richaud , Caroline Lamarche , Myriam Khalili, Mathieu Goupil, Ksenia Bezverbnaya, Jonathan L Bramson , Jean-Sébastien Delisle
      DOI 10.1158/2326-6066.CIR-18-0691 PMID 31308016
      Consulter

    • Systematic testing and specificity mapping of alloantigen-specific chimeric antigen receptors in regulatory T cells

      Nicholas Aj Dawson , Caroline Lamarche , Romy E Hoeppli, Peter Bergqvist, Vivian Cw Fung, Emma McIver, Qing Huang, Jana Gillies, Madeleine Speck, Paul C Orban, Jonathan W Bush, Majid Mojibian, Megan K Levings
      DOI 10.1172/jci.insight.123672 PMID 30753169
      Consulter

    • Infectious Disease Risk in Dialysis Patients: A Transdisciplinary Approach

      Caroline Lamarche , Ioan-Andrei Iliuta, Thomas Kitzler
      DOI 10.1177/2054358119839080 PMID 31065378
      Consulter

    • Leukoreduction system chambers are a reliable cellular source for the manufacturing of T-cell therapeutics

      Gabrielle Boudreau, Cédric Carli , Caroline Lamarche , Caroline Rulleau, Guillaume Bonnaure, Sonia Néron , Jean-Sébastien Delisle
      DOI 10.1111/trf.15121 PMID 30589447
      Consulter

    • Guiding regulatory T cells to the allograft

      Caroline Lamarche , Megan K Levings
      DOI 10.1097/MOT.0000000000000483 PMID 29140829
      Consulter

    • Clinical-Scale Rapid Autologous BK Virus-Specific T Cell Line Generation From Kidney Transplant Recipients With Active Viremia for Adoptive Immunotherapy

      Caroline Lamarche , Julie Orio, Victoria Georges-Tobar, Thomas Pincez, Mathieu Goupil, Amina Dahmani, Cedric Carli, Ann Brasey , Lambert Busque , Jean-Sébastien Delisle
      DOI 10.1097/TP.0000000000001698 PMID 28230645
      Consulter

    • Association of Neutrophil-to-Lymphocyte Ratio With Inflammation and Erythropoietin Resistance in Chronic Dialysis Patients

      Jérôme Pineault , Caroline Lamarche , Jean-Philippe Lafrance, Georges Ouellet, Martine Leblanc, Vincent Pichette, Sarah Bezzaoucha, Michel Vallée
      DOI 10.1177/2054358117735563 PMID 29147572
      Consulter

    • Conversion of oral alfacalcidol to oral calcitriol in the treatment of secondary hyperparathyroidism in chronic hemodialysis patients

      Sandrine Rauscher, Jean-Philippe Lafrance, Vincent Pichette, Robert Z Bell, Katherine Desforges, Laurence Lepage, Georges Ouellet, Denis Ouimet, Martine Leblanc , Caroline Lamarche , Sarah Bezzaoucha, Michel Vallee
      DOI 10.1007/s11255-016-1446-1 PMID 27822674
      Consulter

    • Efficacy of Acute Cellular Rejection Treatment According to Banff Score in Kidney Transplant Recipients: A Systematic Review

      Caroline Lamarche , Jean-Maxime Côté, Lynne Sénécal, Héloïse Cardinal
      DOI 10.1097/TXD.0000000000000626 PMID 27990480
      Consulter

    • BK Polyomavirus and the Transplanted Kidney: Immunopathology and Therapeutic Approaches

      Caroline Lamarche , Julie Orio, Suzon Collette, Lynne Senécal, Marie-Josée Hébert, Édith Renoult, Lee Anne Tibbles , Jean-Sébastien Delisle
      DOI 10.1097/TP.0000000000001333 PMID 27391196
      Consulter

    • Retroperitoneal fibrosis: retrospective descriptive study on clinical features and management

      Ann-Sophie Laroche, Robert Z Bell, Sarah Bezzaoucha, Eva Földes , Caroline Lamarche , Michel Vallée
      DOI 10.2147/RRU.S115448 Abstract PMID 27822461
      Consulter

    • Effects of Chronic Renal Failure on Brain Cytochrome P450 in Rats

      Judith Naud, Jessica Harding , Caroline Lamarche , Stephanie Beauchemin, Francois A Leblond, Vincent Pichette
      DOI 10.1124/dmd.116.070052 PMID 27271372
      Consulter

    • Pharmacokinetic and Dynamic of Furosemide in Peritoneal Dialysis Patients

      Caroline Lamarche , Maude Pichette, Denis Ouimet, Michel Vallée, Robert Bell, Georges Ouellet, John Stewart, Vincent Pichette
      DOI 10.3747/pdi.2014.00328 PMID 26838993
      Consulter

    • Treatment of Polyomavirus-Associated Nephropathy With the Association of Sirolimus and Leflunomide

      Caroline Lamarche , Anne Boucher, Raymond Dandavino, Lynne Senécal, Suzon Collette, Duy Tran, Michel Vallée
      PMID 26643679
      Consulter

    • Efficacy of calcitriol compared to alfacalcidol for the treatment of secondary hyperparathyroidism in peritoneal dialysis patients

      Sarah Bezzaoucha, Jean-Philippe Lafrance, Denis Ouimet, Vincent Pichette, Robert Bell , Caroline Lamarche , Michel Vallée
      DOI 10.5414/CP202430 PMID 26308178
      Consulter

    • Presumed paradoxical embolus in a patient with diabetic ketoacidosis

      Catherine Langevin , Caroline Lamarche , Robert Z Bell, Michel Vallée
      DOI 10.2147/IJGM.S87521 PMID 26445558
      Consulter

    • The effect of lanthanum carbonate on metabolic acidosis in patients with chronic kidney disease stage IV, V and V-D

      William Beaubien-Souligny, Sarah Bezzaoucha, Vincent Pichette, Jean-Philippe Lafrance, Robert Bell , Caroline Lamarche , Denis Ouimet, Michel Vallee
      DOI 10.1007/s11255-015-1003-3 PMID 25982583
      Consulter

    • Effect of parathyroidectomy on vitamin D levels

      Caroline Lamarche , François Leblond, Denis Ouimet, Vincent Pichette
      DOI 10.1007/s00268-014-2836-0 PMID 25322699
      Consulter

    • Hemodialysis effects on phenytoin pharmacokinetics

      Sarah Bezzaoucha, Amine Merghoub , Caroline Lamarche , Vincent Pichette, Jean-Philippe Lafrance, Louis-Philippe Laurin, Michel Vallée, Robert Robitaille, Martine Leblanc, Robert Bell
      DOI 10.1007/s00228-013-1628-z PMID 24390629
      Consulter