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Centre intégré universitaire de santé
et de services sociaux de l'Est-de-l'Île-de-Montréal

Centre intégré universitaire de santé et de services sociaux de l'Est-de-l'Île-de-Montréal

Sandra Cohen, M.D.

Sandra Cohen

Hématologue-greffeuse, Professeure agrégée de clinique

L'équipe de l’IHOT

Chercheur-clinicien

Contact

Tél. : 514 252-3404

Les intérêts de recherche de Dre Sandra Cohen portent sur la greffe de sang de cordon ombilical et plus particulièrement sur l’expansion des cellules souches du sang de cordon avec la molécule UM171, sur les syndromes lymphoprolifératifs et sur la réduction des infections post-allogreffe.

 

  • Entrée en poste à l’Hôpital Maisonneuve-Rosemont : 2001

 

Formation :

  • Fellowship en greffe de cellules souches hématopoïétiques : City of Hope National Cancer Center, Californie (États-Unis)
  • Résidences en médecine interne et hématologie : Université McGill, Montréal (Canada), 1993-1998
  • Doctorat en médecine : Université de Sherbrooke (Canada), 1989-1993
     

Découvrez ses publications

  • Improved outcomes of UM171-expanded cord blood transplantation compared with other graft sources: real-world evidence

    Sandra Cohen , Nadia Bambace , Imran Ahmad , Jean Roy , Xiaoying Tang, Mei-Jie Zhang, Linda Burns, Frédéric Barabé , Léa Bernard , Jean-Sébastien Delisle , Thomas Kiss , Sylvie Lachance , Denis-Claude Roy , Olivier Veilleux , Guy Sauvageau
    DOI 10.1182/bloodadvances.2023010599 PMID 37467030
    Consulter
  • Corrigendum to' UM171 expansion of cord blood improves donor availability and HLA matching for all patients, including minorities' [Transplantation and Cellular Therapy 28/7 (2022) 410-410

    Maude Dumont-Lagacé, Albert Feghaly, Marie-Christine Meunier, Marcie Finney, Wouter Van't Hof, Emeline Masson Frenet , Guy Sauvageau , Sandra Cohen
    DOI 10.1016/j.jtct.2023.08.024 PMID 37726096
    Consulter
  • International Society for Cell & Gene Therapy Stem Cell Engineering Committee: Cellular therapies for the treatment of graft-versus-host-disease after hematopoietic stem cell transplant

    Moises Garcia-Rosa, Allistair Abraham, Alice Bertaina, Senthil Velan Bhoopalan, Carmem Bonfim , Sandra Cohen , Amy DeZern, Chrystal Louis, Joseph Oved, Mara Pavel-Dinu, Duncan Purtill , Annalisa Ruggeri , Athena Russell, Akshay Sharma, Robert Wynn, Jaap Jan Boelens, Susan Prockop
    DOI 10.1016/j.jcyt.2023.02.007 PMID 36941149
    Consulter
  • Transplant for non-malignant disorders: an International Society for Cell & Gene Therapy Stem Cell Engineering Committee report on the role of alternative donors, stem cell sources and graft engineering

    Orly R Klein, Carmem Bonfim, Allistair Abraham, Annalisa Ruggeri, Duncan Purtill , Sandra Cohen , Robert Wynn, Athena Russell, Akshay Sharma, Rachele Ciccocioppo, Susan Prockop, Jaap Jan Boelens, Alice Bertaina
    DOI 10.1016/j.jcyt.2022.12.005 PMID 36710227
    Consulter
  • Towards clinically meaningful expansion of human HSCs

    Maria Florencia Tellechea, Jalila Chagraoui , Sandra Cohen , Guy Sauvageau
    DOI 10.1038/s41422-023-00817-z PMID 37161072
    Consulter
  • Bortezomib Maintenance After Allogeneic Transplantation in Newly Diagnosed Myeloma Patients Results in Decreased Incidence and Severity of Chronic GVHD

    DOI 10.1016/j.jtct.2022.10.022 PMID 36334654
    Consulter
  • Impact of Implementing a Bendamustine-Based Conditioning Regimen on Outcomes of Autologous Stem Cell Transplantation in Lymphoma while Novel Cellular Therapies Emerge

    Sylvie Lachance , Alex Bourguignon, Josie-Anne Boisjoly, Philippe Bouchard , Imran Ahmad , Nadia Bambace , Léa Bernard , Sandra Cohen , Jean-Sébastien Delisle , Isabelle Fleury , Thomas Kiss , Luigina Mollica , Denis-Claude Roy , Guy Sauvageau , Olivier Veilleux , Justine Zehr, Miguel Chagnon , Jean Roy
    DOI 10.1016/j.jtct.2022.10.003 PMID 36243319
    Consulter
  • Viral infection in hematopoietic stem cell transplantation: an International Society for Cell & Gene Therapy Stem Cell Engineering Committee review on the role of cellular therapy in prevention and treatment

    Maja Stanojevic, Alice Bertaina, Carmem Bonfim, Rachele Ciccocioppo , Sandra Cohen , Duncan Purtill, Annalisa Ruggeri, Athena Russell, Akshay Sharma, Robert Wynn, Jaap Jan Boelens, Susan Prockop, Allistair Abraham; ISCT working committee on stem cell engineering
    DOI 10.1016/j.jcyt.2022.05.010 PMID 35705447
    Consulter
  • Donor Age and Non-Relapse Mortality: Study of Their Association after HLA-Matched Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndrome

    DOI 10.3390/curroncol29080470 PMID 36005208
    Consulter
  • UM171 Expansion of Cord Blood Improves Donor Availability and HLA Matching For All Patients, Including Minorities

    Maude Dumont-Lagacé, Albert Feghaly, Marie-Christine Meunier, Marcie Finney, Wouter Van't Hof, Emeline Masson Frenet , Guy Sauvageau , Sandra Cohen
    DOI 10.1016/j.jtct.2022.03.016 PMID 35311667
    Consulter
  • An ISCT Stem Cell Engineering Committee Position Statement on Immune Reconstitution: the importance of predictable and modifiable milestones of immune reconstitution to transplant outcomes

    Alice Bertaina, Allistair Abraham, Carmem Bonfim , Sandra Cohen , Duncan Purtill, Annalisa Ruggeri, Daniel Weiss, Robert Wynn, Jaap Jan Boelens, Susan Prockop; ISCT Committee on Stem Cell Engineering
    DOI 10.1016/j.jcyt.2021.09.011 PMID 35331394
    Consulter
  • Real-World Outcomes of Autologous and Allogeneic Hematopoietic Stem Cell Transplantation for Relapsed/Refractory Hodgkin Lymphoma in the Era of Novel Therapies: A Canadian Perspective

    DOI 10.1016/j.jtct.2021.12.005 PMID 34954149
    Consulter
  • Curative therapy for hemoglobinopathies: an International Society for Cell & Gene Therapy Stem Cell Engineering Committee review comparing outcomes, accessibility and cost of ex vivo stem cell gene therapy versus allogeneic hematopoietic stem cell tran...

    Alexis Leonard, Alice Bertaina, Carmem Bonfim , Sandra Cohen , Susan Prockop, Duncan Purtill, Athena Russell, Jaap Jan Boelens, Robert Wynn, Annalisa Ruggeri, Allistair Abraham
    DOI 10.1016/j.jcyt.2021.09.003 PMID 34879990
    Consulter
  • Outcomes in newly diagnosed young or high-risk myeloma patients receiving tandem autologous/allogeneic transplant followed by bortezomib maintenance: a phase II study

    Richard LeBlanc , Imran Ahmad , Rafik Terra, Jean-Samuel Boudreault, David Ogez, Kristopher Lamore , Jean-Sébastien Delisle , Nadia Bambace , Léa Bernard , Sandra Cohen , Thomas Kiss , Sylvie Lachance , Séverine Landais, Émilie Lemieux-Blanchard , Guy Sauvageau , Michael Sebag , Denis-Claude Roy , Jean Roy
    DOI 10.1038/s41409-021-01532-2 PMID 34845367
    Consulter
  • UM171-Expanded Cord Blood Transplants Support Robust T Cell Reconstitution with Low Rates of Severe Infections

    Maude Dumont-Lagacé, Qi Li , Mégane Tanguay , Jalila Chagraoui, Tibila Kientega, Guillaume B Cardin, Ann Brasey, Assya Trofimov, Cédric Carli , Imran Ahmad , Nadia M Bambace , Léa Bernard , Thomas Kiss , Jean Roy , Denis-Claude Roy , Sébastien Lemieux, Claude Perreault, Francis Rodier, Simon Frédéric Dufresne , Lambert Busque , Sylvie Lachance , Guy Sauvageau , Sandra Cohen , Jean-Sébastien Delisle
    DOI 10.1016/j.bbmt.2020.09.031 PMID 33022376
    Consulter
  • Single UM171-expanded cord blood transplant can cure severe idiopathic aplastic anemia in absence of suitable donors

    DOI 10.1111/ejh.13504 PMID 32749758
    Consulter
  • Newly diagnosed multiple myeloma patients treated with tandem auto-allogeneic stem cell transplant have better overall survival with similar outcomes at time of relapse compared to patients who received autologous transplant only

    DOI 10.1111/ctr.14099 PMID 32981146
    Consulter
  • Hematopoietic stem cell transplantation using single UM171-expanded cord blood: a single-arm, phase 1-2 safety and feasibility study

    Sandra Cohen , Jean Roy , Sylvie Lachance , Jean-Sébastien Delisle , Anne Marinier , Lambert Busque , Denis-Claude Roy , Imran Ahmad , Nadia M Bambace , Léa Bernard , Thomas Kiss , Philippe Bouchard, Pierre Caudrelier, Sévérine Landais, Fannie Larochelle, Jalila Chagraoui, Bernhard Lehnertz, Sophie Corneau, Elisa Tomellini, Jeroen J A van Kampen, Jan J Cornelissen, Maude Dumont-Lagacé, Mégane Tanguay, Qi Li , Sébastien Lemieux, Peter W Zandstra , Guy Sauvageau
    DOI 10.1016/S2352-3026(19)30202-9 PMID 31704264
    Consulter
  • Evaluation of the Impact of Autologous Hematopoietic Stem Cell Transplantation on the Quality of Life of Older Patients with Lymphoma

    DOI 10.1016/j.bbmt.2019.09.007 PMID 31521818
    Consulter
  • Allodepleted T-cell immunotherapy after haploidentical haematopoietic stem cell transplantation without severe acute graft-versus-host disease (GVHD) in the absence of GVHD prophylaxis

    Denis-Claude Roy , Sylvie Lachance , Sandra Cohen , Jean-Sébastien Delisle , Thomas Kiss , Guy Sauvageau , Lambert Busque , Imran Ahmad , Léa Bernard , Nadia M Bambace, Radia S Boumédine, Marie-Claude Guertin, Katayoun Rezvani, Stephan Mielke, Claude Perreault , Jean Roy
    DOI 10.1111/bjh.15970 PMID 31135970
    Consulter
  • Outcome of autologous hematopoietic stem cell transplant in older patients with B cell lymphoma when selected for fitness and chemosensitive disease

    DOI 10.1016/j.leukres.2019.01.002 PMID 30654975
    Consulter
  • Cerebral adenovirus endotheliitis presenting as posterior reversible encephalopathy syndrome after allogeneic stem cell transplantation

    DOI 10.1038/bmt.2017.154 PMID 28692025
    Consulter
  • Favorable long-term outcome of patients with multiple myeloma using a frontline tandem approach with autologous and non-myeloablative allogeneic transplantation

    DOI 10.1038/bmt.2015.319 PMID 26691426
    Consulter
  • Small molecule regulation of normal and leukemic stem cells

    Iman Fares, Laura Rivest-Khan , Sandra Cohen , Guy Sauvageau
    DOI 10.1097/MOH.0000000000000151 PMID 26049751
    Consulter
  • Favorable outcomes from allogeneic and autologous stem cell transplantation for patients with transformed nonfollicular indolent lymphoma

    Diego Villa, Anupkumar George, John F Seymour, Cynthia L Toze, Michael Crump, Christina Lee, Rena Buckstein, Douglas A Stewart, David MacDonald, Ronan Foley , Anargyros Xenocostas, Mitchell Sabloff, Neil Chua, Felix Couture, Jean F Larouche , Sandra Cohen , Kerry J Savage, Joseph M Connors, Tony Panzarella, Dennis A Carney, Michael Dickinson, John Kuruvilla
    DOI 10.1016/j.bbmt.2014.07.015 PMID 25042735
    Consulter
  • Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal

    Iman Fares, Jalila Chagraoui, Yves Gareau, Stéphane Gingras, Réjean Ruel, Nadine Mayotte, Elizabeth Csaszar, David J H F Knapp, Paul Miller, Mor Ngom, Suzan Imren , Denis-Claude Roy , Kori L Watts, Hans-Peter Kiem, Robert Herrington, Norman N Iscove, R Keith Humphries, Connie J Eaves , Sandra Cohen , Anne Marinier, Peter W Zandstra , Guy Sauvageau
    DOI 10.1126/science.1256337 PMID 25237102
    Consulter
  • Safety and cost-effectiveness of outpatient autologous stem cell transplantation in patients with multiple myeloma

    DOI 10.1016/j.bbmt.2012.12.006 PMID 23253556
    Consulter
  • Blood stem cell products: toward sustainable benchmarks for clinical translation

    Elizabeth Csaszar , Sandra Cohen , Peter W Zandstra
    DOI 10.1002/bies.201200118 PMID 23299858
    Consulter
  • Autologous and allogeneic stem-cell transplantation for transformed follicular lymphoma: a report of the Canadian blood and marrow transplant group

    Diego Villa, Michael Crump, Tony Panzarella, Kerry J Savage, Cynthia L Toze, Douglas A Stewart, David A MacDonald, Rena Buckstein, Christina Lee, Mohsen Alzahrani, Morel Rubinger, Ronan Foley , Anargyros Xenocostas, Mitchell Sabloff, Alexandra Muccilli, Neil Chua, Felix Couture, Jean-François Larouche , Sandra Cohen , Joseph M Connors, Kimberley Ambler, Abdulwahab Al-Tourah, Khaled M Ramadan, John Kuruvilla
    DOI 10.1200/JCO.2012.44.0693 PMID 23401459
    Consulter
  • Defining the role of sirolimus in the management of graft-versus-host disease: from prophylaxis to treatment

    DOI 10.1016/j.bbmt.2012.06.020 PMID 22771839
    Consulter
  • False-positive human T-lymphotropic virus serology after intravenous immunoglobulin transfusion

    Sophie Savary Bélanger, Douglas Fish, John Kim , Sandra Cohen
    DOI 10.1503/cmaj.120019 PMID 22927508
    Consulter
  • Tandem autologous-allogeneic nonmyeloablative sibling transplantation in relapsed follicular lymphoma leads to impressive progression-free survival with minimal toxicity

    DOI 10.1016/j.bbmt.2011.11.028 PMID 22155507
    Consulter
  • Cardiac tamponade potentially related to sirolimus following cord blood transplantation

    DOI 10.1038/bmt.2011.44 PMID 21399672
    Consulter
  • Allogeneic hematopoietic stem cell collection from a donor with end-stage renal disease

    DOI 10.1038/bmt.2011.31 PMID 21358687
    Consulter
  • Incidence and prognostic value of eosinophilia in chronic graft-versus-host disease after nonmyeloablative hematopoietic cell transplantation

    DOI 10.1016/j.bbmt.2011.04.012 PMID 21601640
    Consulter
  • High incidence of herpes zoster in nonmyeloablative hematopoietic stem cell transplantation

    Shih Hann Su, Valérie Martel-Laferrière, Annie-Claude Labbé, David R Snydman, David Kent, Michel Laverdière, Claire Béliveau, Tanya Logvinenko , Sandra Cohen , Sylvie Lachance , Thomas Kiss , Jean Roy
    DOI 10.1016/j.bbmt.2010.10.025 PMID 20977944
    Consulter
  • Photodepletion differentially affects CD4+ Tregs versus CD4+ effector T cells from patients with chronic graft-versus-host disease

    Jean-Philippe Bastien 1, Gorazd Krosl, Cynthia Therien, Marissa Rashkovan, Christian Scotto , Sandra Cohen , David S Allan, Donna Hogge, R Maarten Egeler, Claude Perreault , Denis-Claude Roy
    DOI 10.1182/blood-2010-03-273193 PMID 20798236
    Consulter
  • Allogeneic stem cell transplantation provides durable disease control in poor-risk chronic lymphocytic leukemia: long-term clinical and MRD results of the German CLL Study Group CLL3X trial

    Peter Dreger, Hartmut Döhner, Matthias Ritgen, Sebastian Böttcher, Raymonde Busch, Sascha Dietrich, Donald Bunjes , Sandra Cohen , Jörg Schubert, Ute Hegenbart, Dietrich Beelen, Matthias Zeis, Michael Stadler, Justin Hasenkamp, Lutz Uharek, Christof Scheid, Andreas Humpe, Thorsten Zenz, Dirk Winkler, Michael Hallek, Michael Kneba, Norbert Schmitz, Stephan Stilgenbauer , German CLL Study Group
    DOI 10.1182/blood-2010-03-275420 PMID 20595516
    Consulter
  • Late acute renal failure due to bilateral kidney infiltration by ALL as single manifestation of relapse after allogeneic transplantation

    DOI 10.1038/bmt.2009.246 PMID 19767785
    Consulter
  • Munchausen's syndrome in the allogeneic stem cell transplantation setting: a rare but potentially devastating condition

    M-A Archambault-Grenier , Jean Roy , N Beauchemin , Sandra Cohen , Sylvie Lachance , Thomas Kiss
    DOI 10.1038/bmt.2009.192 PMID 19668234
    Consulter
  • Graft-versus-host disease prophylaxis with tacrolimus and mycophenolate mofetil in HLA-matched nonmyeloablative transplant recipients is associated with very low incidence of GVHD and nonrelapse mortality

    Waleed Sabry , Richard LeBlanc , Annie-Claude Labbé , Guy Sauvageau , Stephen Couban , Thomas Kiss , Lambert Busque , Sandra Cohen , Sylvie Lachance , Denis-Claude Roy , Jean Roy
    DOI 10.1016/j.bbmt.2009.04.004 PMID 19589481
    Consulter
  • Diphyllobothriasis, a rare cause of profuse diarrhea following autologous transplantation

    DOI 10.1038/bmt.2008.439 PMID 19169286
    Consulter
  • Quantitative MRD monitoring identifies distinct GVL response patterns after allogeneic stem cell transplantation for chronic lymphocytic leukemia: results from the GCLLSG CLL3X trial

    M Ritgen, S Böttcher, S Stilgenbauer, D Bunjes, J Schubert , Sandra Cohen , A Humpe, M Hallek, M Kneba, N Schmitz, H Döhner, P Dreger; German CLL Study Group
    DOI 10.1038/leu.2008.96 PMID 18418404
    Consulter
  • High incidence of invasive aspergillosis associated with intestinal graft-versus-host disease following nonmyeloablative transplantation

    Annie-Claude Labbé, Shi Hann Su, Michel Laverdière, Jacques Pépin, Carlos Patiño , Sandra Cohen , Thomas Kiss , Sylvie Lachance , Guy Sauvageau , Lambert Busque , Denis-Claude Roy , Jean Roy
    DOI 10.1016/j.bbmt.2007.06.013 PMID 17889356
    Consulter
  • Allogeneic hematopoietic cell transplantation following reduced intensity conditioning for treatment of myelofibrosis

    David S Snyder, Joycelynne Palmer, Anthony S Stein, Vinod Pullarkat, Firoozeh Sahebi , Sandra Cohen , Nayana Vora, Karl Gaal, Ryo Nakamura, Stephen J Forman
    DOI 10.1016/j.bbmt.2006.06.014 PMID 17085309
    Consulter
  • Efficacy of mycophenolate mofetil in the treatment of chronic graft-versus-host disease

    Francisco Lopez, Pablo Parker, Auayporn Nademanee, Roberto Rodriguez, Zaid Al-Kadhimi, Ravi Bhatia , Sandra Cohen , Peter Falk, Henry Fung, Mark Kirschbaum, Amrita Krishnan, Neil Kogut, Arturo Molina, Ryotaro Nakamura, Margaret O'Donnell, Leslie Popplewell, Vinod Pullarkat, Joseph Rosenthal, Firoozeh Sahebi, Eileen Smith, David Snyder, George Somlo, Ricardo Spielberger , Anthony Stein, Robert Sweetman, Jasmine Zain, Stephen Forman
    DOI 10.1016/j.bbmt.2005.01.011 PMID 15812396
    Consulter
  • Maintaining high autopsy rates in a Canadian blood and marrow transplant program: preserving a diagnostic and research tool

    D S Allan, R Bélanger , Lambert Busque , Sandra Cohen , D Fish , Denis-Claude Roy , Jean Roy
    DOI 10.1038/sj.bmt.1704869 PMID 15735662
    Consulter
  • Cyclosporine and mycophenolate mofetil prophylaxis with fludarabine and melphalan conditioning for unrelated donor transplantation: a prospective study of 22 patients with hematologic malignancies

    R Rodriguez, P Parker, A Nademanee, D Smith, M R O'Donnell, A Stein, D S Snyder, H C Fung, A Y Krishnan, L Popplewell , Sandra Cohen , G Somlo, M Angelopoulou, Z Al-Kadhimi, P M Falk, R Spielberger, N Kogut, F Sahebi, D Senitzer, M Slovak, J Schriber, S J Forman
    DOI 10.1038/sj.bmt.1704493 PMID 15064696
    Consulter
  • Chronic myeloid leukemia with an e13a3 BCR-ABL fusion: benign course responsive to imatinib with an RT-PCR advisory

    David S Snyder, Ross McMahon , Sandra Cohen , Marilyn L Slovak
    DOI 10.1002/ajh.10456 PMID 14755375
    Consulter
  • A long-term follow-up report on allogeneic stem cell transplantation for patients with primary refractory acute myelogenous leukemia: impact of cytogenetic characteristics on transplantation outcome

    H C Fung, A Stein, M l Slovak, M R O'donnell, D S Snyder , Sandra Cohen , D Smith, A Krishnan, R Spielberger, R Bhatia, S Bhatia, P Falk, A Molina, A Nademanee, P Parker, R Rodriguez, J Rosenthal, R Sweetman, N Kogut, F Sahebi, L Popplewell, N Vora, G Somlo, K Margolin, W Chow, E Smith, S J Forman
    DOI 10.1016/j.bbmt.2003.08.004 PMID 14677116
    Consulter
  • Reduced-intensity allogeneic stem cell transplantation for patients whose prior autologous stem cell transplantation for hematologic malignancy failed

    H C Fung , Sandra Cohen , R Rodriguez, D Smith, A Krishnan, G Somlo, F Sahebi, D Senitzer, M R O'Donnell, A Stein, D S Snyder, R Spielberger, R Bhatia, P Falk, A Molina, A Nademanee, P Parker, N Kogut, L Popplewell, N Vora, K Margolin, S J Forman
    DOI 10.1016/s1083-8791(03)00241-6 PMID 14569561
    Consulter