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Centre intégré universitaire de santé
et de services sociaux de l'Est-de-l'Île-de-Montréal

Centre intégré universitaire de santé et de services sociaux de l'Est-de-l'Île-de-Montréal

Jean-Sébastien Delisle, M.D., Ph. D.

Jean-Sébastien Delisle

Hématologue-greffeur, Professeur titulaire

L'équipe de l’IHOT

Chercheur-clinicien

Contact

Tél. : 514 252-3404

Dr Jean-Sébastien Delisle consacre ses recherches à l’immunothérapie cellulaire et, plus précisément, à la biologie des lymphocytes T ainsi qu'à l’impact de leur différenciation et fonction dans le développement et l’évaluation d’immunothérapies cellulaires. 

 

  • Chercheur chevronné FRQS (2023-2027)
  • Coordonnateur médical du CETC (Centre d’excellence en thérapie cellulaire) HMR
  • Directeur de l'unité de recherche en Immunologie du cancer et transplantation du Centre de recherche HMR
  • Membre du Comité de priorisation clinique et recherche de l'IHOT
  • Membre du Comité de direction de l'IHOT
  • Directeur du Réseau de thérapie cellulaire, tissulaire et génique du Québec (ThéCell)
  • Chercheur associé de l’Institut de recherche en immunologie et en cancérologie (IRIC)
  • Entrée en poste à l’Hôpital Maisonneuve-Rosemont : 2010

 

Formation :

  • Doctorat en sciences biomédicales : Université de Montréal (Canada), 2004-2010
  • Résidences en médecine interne et hématologie : Université McGill, Montréal (Canada), 1999-2004
  • Doctorat en médecine : Université de Montréal (Canada), 1994-1999

Découvrez ses publications

  • A Pilot Study of UM171-Expanded Cord Blood Grafts for Tandem Auto/Allogeneic Hematopoietic Cell Transplant in High and Ultra-High-Risk Myeloma Patients

    Jean Roy , Sandra Cohen , Guy Sauvageau , Imran Ahmad , Valentyn Fournier, Rafik Terra, Pierre Caudrelier, Stéphanie Thiant, Gabrielle Thauvette, Nadia Bambace , Jean-Sébastien Delisle , Sylvie Lachance , Thomas Kiss , Léa Bernard , Denis-Claude Roy , Olivier Veilleux , Richard LeBlanc
    DOI 10.1016/j.jtct.2024.10.008 PMID 39419177
    Consulter
  • Approach to autologous stem cell transplantation in a patient with severe cold agglutinin disease, a case report

    DOI 10.1111/trf.18147 PMID 39876551
    Consulter
  • Successful desensitization of donor-specific antibodies in a single cord blood transplant recipient

    Tanguay M , Sandra Cohen , Ménard I, Meunier MC , Jean-Sébastien Delisle , Jean Roy , Olivier Veilleux , Imran Ahmad
    DOI 10.1080/16078454.2024.2448552 PMID 39763113
    Consulter
  • Characterization and effective expansion of CD4-CD8- TCRαβ+ T cells from individuals living with type 1 diabetes

    J Ernesto Fajardo-Despaigne, Félix Lombard-Vadnais, Adam-Nicolas Pelletier, Aïnhoa Olazabal, Lucie Boutin, Sarah Pasquin, Valérie Janelle, Laurent Legault , Jean-Sébastien Delisle , Erin E Hillhouse, Lise Coderre , Sylvie Lesage
    DOI 10.1016/j.omtm.2024.101400 PMID 39877593
    Consulter
  • Using machine learning for personalized prediction of longitudinal coronavirus disease 2019 vaccine responses in transplant recipients

    Azarfar G, Sun Y, Pasini E, Sidhu A, Brudno M, Humar A, Kumar D, Bhat M, Ferreira VH; PREVenT Study Group; PREVenT-COVID Group investigators , Jean-Sébastien Delisle
    DOI 10.1016/j.ajt.2024.11.033 PMID 39643006
    Consulter
  • The Long-Acting Glucagon-Like Peptide-2 Analog Apraglutide Enhances Intestinal Protection and Survival After Chemotherapy and Allogeneic Transplantation in Mice

    Mark D Minden, Cindy Audiger, Geneviève Chabot-Roy , Sylvie Lesage , Jean-Sébastien Delisle , Barbara Biemans, Violetta Dimitriadou
    DOI 10.12659/AOT.945249 PMID 39497378
    Consulter
  • Abstracts of the Cell Therapy Transplant Canada 2023 Annual Conference

    Stephanie A Maier , Imran Ahmad , Tobias Berg, Susan Berrigan, Mahmoud Elsawy, Alejandro Garcia-Horton, Wilson Lam, Alix Lapworth, Luciana Melo Garcia, Ravi M Shah, Ram Vasudevan Nampoothiri , Jean-Sébastien Delisle
    DOI 10.3390/curroncol31060223 PMID 38920707
    Consulter
  • Armstrong strain lymphocytic choriomeningitis virus infection after accidental laboratory exposure

    Laurence Caron , Jean-Sébastien Delisle , James E Strong, Yvon Deschambault, Félix Lombard-Vadnais, Annie-Claude Labbé , Sylvie Lesage
    DOI 10.1186/s12985-023-02258-x PMID 38087355
    Consulter
  • SARS-CoV-2 Variants Omicron BA.4/5 and XBB.1.5 Significantly Escape T Cell Recognition in Solid-organ Transplant Recipients Vaccinated Against the Ancestral Strain

    Torin Halvorson, Sabine Ivison, Qing Huang, Gale Ladua, Demitra M Yotis, Dhiraj Mannar, Sriram Subramaniam, Victor H Ferreira, Deepali Kumar, Sara Belga, Megan K Levings, PREVenT Study Group , Jean-Sébastien Delisle
    DOI 10.1097/TP.0000000000004873 PMID 38012843
    Consulter
  • Improved outcomes of UM171-expanded cord blood transplantation compared with other graft sources: real-world evidence

    Sandra Cohen , Nadia Bambace , Imran Ahmad , Jean Roy , Xiaoying Tang, Mei-Jie Zhang, Linda Burns, Frédéric Barabé , Léa Bernard , Jean-Sébastien Delisle , Thomas Kiss , Sylvie Lachance , Denis-Claude Roy , Olivier Veilleux , Guy Sauvageau
    DOI 10.1182/bloodadvances.2023010599 PMID 37467030
    Consulter
  • CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax

    Mathieu Neault, Charles-Étienne Lebert-Ghali, Marilaine Fournier, Caroline Capdevielle, Elizabeth A R Garfinkle, Alyssa Obermayer, Anitria Cotton, Karine Boulay , Christina Sawchyn, Sarah St-Amand, Kamy H Nguyen, Béatrice Assaf, François E Mercier , Jean-Sébastien Delisle , Elliot A Drobetsky, Laura Hulea, Timothy I Shaw, Johannes Zuber, Tanja A Gruber, Heather J Melichar, Frédérick A Mallette
    DOI 10.1016/j.celrep.2023.113084 PMID 37716355
    Consulter
  • Omicron BA.4/5 Neutralization and T-Cell Responses in Organ Transplant Recipients After Booster Messenger RNA Vaccine: A Multicenter Cohort Study

    Victor H Ferreira, Matthew Ierullo, Faranak Mavandadnejad, Alexandra Kurtesi, Queenie Hu, W Rod Hardy, Victoria G Hall, Natalia Pinzon, Demitra Yotis , Anne-Claude Gingras, Sara Belga, Sarah Shalhoub, Marie-Josée Hébert, Atul Humar, Dima Kabbani, Deepali Kumar , Jean-Sébastien Delisle
    DOI 10.1093/cid/ciad175 PMID 36975097
    Consulter
  • Immunogenicity, Safety, and Breakthrough Severe Acute Respiratory Syndrome Coronavirus 2 Infections After Coronavirus Disease 2019 Vaccination in Organ Transplant Recipients: A Prospective Multicenter Canadian Study

    Dima Kabbani,corresponding author Demitra M Yotis, Victor H Ferreira, Sarah Shalhoub, Sara Belga, Varalika Tyagi, Matthew Ierullo, Vathany Kulasingam, Marie-Josée Hébert, Lori West , Jean-Sébastien Delisle , Normand Racine, Sacha A De Serres, Héloïse Cardinal, Mélanie Dieudé, Atul Humar, Deepali Kumar
    DOI 10.1093/ofid/ofad200 PMID 37213422
    Consulter
  • Immature and mature bone marrow-derived dendritic cells exhibit distinct intracellular mechanical properties

    Antoine Leblanc-Hotte, Cindy Audiger, Geneviève Chabot-Roy, Félix Lombard-Vadnais , Jean-Sébastien Delisle , Yves-Alain Peter , Sylvie Lesage
    DOI 10.1038/s41598-023-28625-w PMID 36737470
    Consulter
  • Impact of Implementing a Bendamustine-Based Conditioning Regimen on Outcomes of Autologous Stem Cell Transplantation in Lymphoma while Novel Cellular Therapies Emerge

    Sylvie Lachance , Alex Bourguignon, Josie-Anne Boisjoly, Philippe Bouchard , Imran Ahmad , Nadia Bambace , Léa Bernard , Sandra Cohen , Jean-Sébastien Delisle , Isabelle Fleury , Thomas Kiss , Luigina Mollica , Denis-Claude Roy , Guy Sauvageau , Olivier Veilleux , Justine Zehr, Miguel Chagnon , Jean Roy
    DOI 10.1016/j.jtct.2022.10.003 PMID 36243319
    Consulter
  • Bortezomib Maintenance After Allogeneic Transplantation in Newly Diagnosed Myeloma Patients Results in Decreased Incidence and Severity of Chronic GVHD

    DOI 10.1016/j.jtct.2022.10.022 PMID 36334654
    Consulter
  • Blasts in context: the impact of the immune environment on acute myeloid leukemia prognosis and treatment

    Yasmina Serroukh , Josée Hébert , Lambert Busque , François Mercier , Chris Rudd , Sarit Assouline , Sylvie Lachance , Jean-Sébastien Delisle
    DOI 10.1016/j.blre.2022.100991 PMID 35941029
    Consulter
  • Abstracts of the Cell Therapy Transplant Canada 2022 Annual Conference

    Stephanie A Maier, Tobias Berg, Susan Berrigan, Jonathan Bramson, Chris Bredeson, Guy Cantin, Andrew Daly, Gwynivere A Davies, Mahmoud Elsawy , Alejandro Garcia-Horton, Wilson Lam, Alix Lapworth, Kylie Lepic, Luciana Melo Garcia, Kirk R Schultz , Ram Vasudevan Nampoothiri, Darrell White , Jean-Sébastien Delisle
    DOI 10.3390/curroncol29120783 PMID 36547197
    Consulter
  • Safety and Immunogenicity After a Three-Dose SARS-CoV-2 Vaccine Schedule in Allogeneic Stem Cell Transplant Recipients

    Muneyoshi Kimura, Victor H Ferreira, Sagar Kothari, Ivan Pasic, Jonas I Mattsson, Vathany Kulasingam, Atul Humar, Allison Mah , Jean-Sébastien Delisle , Matthew Ierullo, Beata Majchrzak-Kita, Deepali Kumar, Seyed M Hosseini-Moghaddam
    DOI 10.1016/j.jtct.2022.07.024 PMID 35914727
    Consulter
  • Combined PD-L1 and TIM3 blockade improves expansion of fit human CD8+ antigen-specific T cells for adoptive immunotherapy

    Shirin Lak, Valérie Janelle, Anissa Djedid, Gabrielle Boudreau, Ann Brasey, Véronique Lisi, Ali Smaani, Cédric Carli , Lambert Busque , Vincent-Philippe Lavallée , Jean-Sébastien Delisle
    DOI 10.1016/j.omtm.2022.09.016 PMID 36320412
    Consulter
  • Donor Age and Non-Relapse Mortality: Study of Their Association after HLA-Matched Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndrome

    DOI 10.3390/curroncol29080470 PMID 36005208
    Consulter
  • Addition of elotuzumab to lenalidomide and dexamethasone for patients with newly diagnosed, transplantation ineligible multiple myeloma (ELOQUENT-1): an open-label, multicentre, randomised, phase 3 trial

    Meletios A Dimopoulos, Paul G Richardson, Nizar J Bahlis, Sebastian Grosicki, Michele Cavo, Meral Beksaç, Wojciech Legieć, Anna M Liberati, Hartmut Goldschmidt , Andrew Belch, Hila Magen, Alessandra Larocca, Jacob P Laubach, Maria T Petrucci, Donna Reece, Darrell White, María-Victoria Mateos, Ivan Špička, Mihaela Lazaroiu , Jesús Berdeja, Jonathan L Kaufman, Ying-Ming Jou, Alex Ganetsky, Mihaela Popa McKiver, Sagar Lonial, Katja Weisel; ELOQUENT-1 investigators , Jean-Sébastien Delisle
    DOI 10.1016/S2352-3026(22)00103-X PMID 35550060
    Consulter
  • Real-World Outcomes of Autologous and Allogeneic Hematopoietic Stem Cell Transplantation for Relapsed/Refractory Hodgkin Lymphoma in the Era of Novel Therapies: A Canadian Perspective

    DOI 10.1016/j.jtct.2021.12.005 PMID 34954149
    Consulter
  • Early free light chain reduction following treatment initiation predicts favorable outcome in intact immunoglobulin myeloma

    Jean-Sébastien Claveau , Sophie Savary Bélanger , Imran Ahmad , Jean-Sébastien Delisle , Vincent De Guire , Jean Roy , Richard LeBlanc
    DOI 10.1038/s41408-021-00600-6 PMID 34987163
    Consulter
  • Outcomes in newly diagnosed young or high-risk myeloma patients receiving tandem autologous/allogeneic transplant followed by bortezomib maintenance: a phase II study

    Richard LeBlanc , Imran Ahmad , Rafik Terra, Jean-Samuel Boudreault, David Ogez, Kristopher Lamore , Jean-Sébastien Delisle , Nadia Bambace , Léa Bernard , Sandra Cohen , Thomas Kiss , Sylvie Lachance , Séverine Landais, Émilie Lemieux-Blanchard , Guy Sauvageau , Michael Sebag , Denis-Claude Roy , Jean Roy
    DOI 10.1038/s41409-021-01532-2 PMID 34845367
    Consulter
  • p16INK4a Regulates Cellular Senescence in PD-1-Expressing Human T Cells

    Valérie Janelle, Mathieu Neault, Marie-Ève Lebel, Dave Maurice De Sousa, Salix Boulet, Ludovic Durrieu, Cédric Carli, Chloé Muzac, Sébastien Lemieux, Nathalie Labrecque, Heather J Melichar, Frédérick A Mallette , Jean-Sébastien Delisle
    DOI 10.3389/fimmu.2021.698565 PMID 34434190
    Consulter
  • CD5 levels define functionally heterogeneous populations of naïve human CD4+ T cells

    Aditi Sood, Marie-Ève Lebel, Mengqi Dong, Marilaine Fournier, Suzanne J Vobecky, Élie Haddad , Jean-Sébastien Delisle , Judith N Mandl, Nienke Vrisekoop, Heather J Melichar
    DOI 10.1002/eji.202048788 PMID 33682083
    Consulter
  • Myeloid-resident neuropilin-1 promotes choroidal neovascularization while mitigating inflammation

    Elisabeth M M A Andriessen, François Binet, Frédérik Fournier, Masayuki Hata, Agnieszka Dejda, Gaëlle Mawambo, Sergio Crespo‐Garcia, Frédérique Pilon, Manuel Buscarlet, Karine Beauchemin, Véronique Bougie , Garth Cumberlidge, Ariel M Wilson, Steve Bourgault, Flavio A Rezende, Normand Beaulieu , Jean-Sébastien Delisle , Przemyslaw Sapieha
    DOI 10.15252/emmm.201911754 PMID 33876574
    Consulter
  • Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes

    Grégory Ehx, Jean-David Larouche, Chantal Durette, Jean-Philippe Laverdure, Leslie Hesnard, Krystel Vincent, Marie-Pierre Hardy, Catherine Thériault, Caroline Rulleau, Joël Lanoix, Eric Bonneil, Albert Feghaly, Anca Apavaloaei , Nandita Noronha, Céline M Laumont , Jean-Sébastien Delisle , Luca Vago , Josée Hébert , Guy Sauvageau , Sébastien Lemieux, Pierre Thibault, Claude Perreault
    DOI 10.1016/j.immuni.2021.03.001 PMID 33740418
    Consulter
  • UM171-Expanded Cord Blood Transplants Support Robust T Cell Reconstitution with Low Rates of Severe Infections

    Maude Dumont-Lagacé, Qi Li , Mégane Tanguay , Jalila Chagraoui, Tibila Kientega, Guillaume B Cardin, Ann Brasey, Assya Trofimov, Cédric Carli , Imran Ahmad , Nadia M Bambace , Léa Bernard , Thomas Kiss , Jean Roy , Denis-Claude Roy , Sébastien Lemieux, Claude Perreault, Francis Rodier, Simon Frédéric Dufresne , Lambert Busque , Sylvie Lachance , Guy Sauvageau , Sandra Cohen , Jean-Sébastien Delisle
    DOI 10.1016/j.bbmt.2020.09.031 PMID 33022376
    Consulter
  • Single UM171-expanded cord blood transplant can cure severe idiopathic aplastic anemia in absence of suitable donors

    DOI 10.1111/ejh.13504 PMID 32749758
    Consulter
  • Newly diagnosed multiple myeloma patients treated with tandem auto-allogeneic stem cell transplant have better overall survival with similar outcomes at time of relapse compared to patients who received autologous transplant only

    DOI 10.1111/ctr.14099 PMID 32981146
    Consulter
  • T-Cell Immunotherapies Targeting Histocompatibility and Tumor Antigens in Hematological Malignancies

    Valérie Janelle, Caroline Rulleau, Simon Del Testa, Cédric Carli , Jean-Sébastien Delisle
    DOI 10.3389/fimmu.2020.00276 PMID 32153583
    Consulter
  • Hematopoietic stem cell transplantation using single UM171-expanded cord blood: a single-arm, phase 1-2 safety and feasibility study

    Sandra Cohen , Jean Roy , Sylvie Lachance , Jean-Sébastien Delisle , Anne Marinier , Lambert Busque , Denis-Claude Roy , Imran Ahmad , Nadia M Bambace , Léa Bernard , Thomas Kiss , Philippe Bouchard, Pierre Caudrelier, Sévérine Landais, Fannie Larochelle, Jalila Chagraoui, Bernhard Lehnertz, Sophie Corneau, Elisa Tomellini, Jeroen J A van Kampen, Jan J Cornelissen, Maude Dumont-Lagacé, Mégane Tanguay, Qi Li , Sébastien Lemieux, Peter W Zandstra , Guy Sauvageau
    DOI 10.1016/S2352-3026(19)30202-9 PMID 31704264
    Consulter
  • Evaluation of the Impact of Autologous Hematopoietic Stem Cell Transplantation on the Quality of Life of Older Patients with Lymphoma

    DOI 10.1016/j.bbmt.2019.09.007 PMID 31521818
    Consulter
  • TGFβ Programs Central Memory Differentiation in Ex Vivo-Stimulated Human T Cells

    Amina Dahmani, Valérie Janelle, Cédric Carli, Manon Richaud, Caroline Lamarche, Myriam Khalili, Mathieu Goupil, Ksenia Bezverbnaya, Jonathan L Bramson , Jean-Sébastien Delisle
    DOI 10.1158/2326-6066.CIR-18-0691 PMID 31308016
    Consulter
  • Allodepleted T-cell immunotherapy after haploidentical haematopoietic stem cell transplantation without severe acute graft-versus-host disease (GVHD) in the absence of GVHD prophylaxis

    Denis-Claude Roy , Sylvie Lachance , Sandra Cohen , Jean-Sébastien Delisle , Thomas Kiss , Guy Sauvageau , Lambert Busque , Imran Ahmad , Léa Bernard , Nadia M Bambace, Radia S Boumédine, Marie-Claude Guertin, Katayoun Rezvani, Stephan Mielke, Claude Perreault , Jean Roy
    DOI 10.1111/bjh.15970 PMID 31135970
    Consulter
  • Outcome of autologous hematopoietic stem cell transplant in older patients with B cell lymphoma when selected for fitness and chemosensitive disease

    DOI 10.1016/j.leukres.2019.01.002 PMID 30654975
    Consulter
  • Leukoreduction system chambers are a reliable cellular source for the manufacturing of T-cell therapeutics

    Gabrielle Boudreau, Cédric Carli, Caroline Lamarche, Caroline Rulleau, Guillaume Bonnaure, Sonia Néron , Jean-Sébastien Delisle
    DOI 10.1111/trf.15121 PMID 30589447
    Consulter
  • On-chip refractive index cytometry for whole-cell deformability discrimination

    Antoine Leblanc-Hotte, Nadine Sen Nkwe, Geneviève Chabot-Roy, El Bachir Affar , Sylvie Lesage , Jean-Sébastien Delisle , Yves-Alain Peter
    DOI 10.1039/c8lc00938d PMID 30570636
    Consulter
  • Double-Negative T Cell Levels Correlate with Chronic Graft-versus-Host Disease Severity

    Erin E Hillhouse, Stéphanie Thiant, Moutuaata M Moutuou, Félix Lombard-Vadnais, Rachel Parat , Jean-Sébastien Delisle , Imran Ahmad , Denis-Claude Roy , Martin Guimond , Jean Roy , Sylvie Lesage
    DOI 10.1016/j.bbmt.2018.09.008 PMID 30244108
    Consulter
  • A standardized immune phenotyping and automated data analysis platform for multicenter biomarker studies

    Sabine Ivison, Mehrnoush Malek, Rosa V Garcia, Raewyn Broady, Anne Halpin, Manon Richaud, Rollin F Brant, Szu-I Wang, Mathieu Goupil, Qingdong Guan , Peter Ashton, Jason Warren, Amr Rajab, Simon Urschel, Deepali Kumar, Mathias Streitz, Birgit Sawitzki, Stephan Schlickeiser, Janetta J Bijl, Donna A Wall , Jean-Sébastien Delisle , Lori J West, Ryan R Brinkman, Megan K Levings
    DOI 10.1172/jci.insight.121867 PMID 30518691
    Consulter
  • High-throughput refractive index-based microphotonic sensor for enhanced cellular discrimination

    Antoine Leblanc-Hotte, Geneviève Chabot-Roy, Livia Odagiu, Manon Richaud , Sylvie Lesage , Jean-Sébastien Delisle , Yves-Alain Peter
    DOI 10.1016/j.snb.2018.03.087
    Consulter
  • TGF-β in T Cell Biology: Implications for Cancer Immunotherapy

    Amina Dahmani , Jean-Sébastien Delisle
    DOI 10.3390/cancers10060194 PMID 29891791
    Consulter
  • Clinical-Scale Rapid Autologous BK Virus-Specific T Cell Line Generation From Kidney Transplant Recipients With Active Viremia for Adoptive Immunotherapy

    Caroline Lamarche, Julie Orio, Victoria Georges-Tobar, Thomas Pincez, Mathieu Goupil, Amina Dahmani, Cedric Carli, Ann Brasey , Lambert Busque , Jean-Sébastien Delisle
    DOI 10.1097/TP.0000000000001698 PMID 28230645
    Consulter
  • Cerebral adenovirus endotheliitis presenting as posterior reversible encephalopathy syndrome after allogeneic stem cell transplantation

    DOI 10.1038/bmt.2017.154 PMID 28692025
    Consulter
  • Opportunities and challenges for the cellular immunotherapy sector: a global landscape of clinical trials

    Katherine Bonter, Zackariah Breckenridge , Sylvie Lachance , Jean-Sébastien Delisle , Tania Bubela
    DOI 10.2217/rme-2017-0031 PMID 28850001
    Consulter
  • More Haste, Less Speed: Could Public-Private Partnerships Advance Cellular Immunotherapies?

    Tania Bubela, Katherine Bonter , Sylvie Lachance , Jean-Sébastien Delisle , E Richard Gold
    DOI 10.3389/fmed.2017.00134 PMID 28861415
    Consulter
  • Do We Need Full Donor Chimerism? How Alloreactive Cell Therapies without Substantial Engraftment Might Treat Hematologic Cancers

    Elizabeth F Krakow, Hui-Sheng Ai, Brian Shaffer , Jean-Sébastien Delisle , Kai-Xun Hu, Anthony D Sung
    DOI 10.2174/1389450116666150304103849 PMID 25738297
    Consulter
  • VEGF Requires the Receptor NRP-1 To Inhibit Lipopolysaccharide-Dependent Dendritic Cell Maturation

    Nougboli A E Oussa, Amina Dahmani, Marie Gomis, Manon Richaud, Emil Andreev, Ali-Reza Navab-Daneshmand, Julie Taillefer, Cédric Carli, Salix Boulet, Laurent Sabbagh , Nathalie Labrecque, Przemyslaw Sapieha , Jean-Sébastien Delisle
    DOI 10.4049/jimmunol.1601116 PMID 27815442
    Consulter
  • BK Polyomavirus and the Transplanted Kidney: Immunopathology and Therapeutic Approaches

    Caroline Lamarche, Julie Orio, Suzon Collette, Lynne Senécal, Marie-Josée Hébert, Édith Renoult, Lee Anne Tibbles , Jean-Sébastien Delisle
    DOI 10.1097/TP.0000000000001333 PMID 27391196
    Consulter
  • Proteogenomic-based discovery of minor histocompatibility antigens with suitable features for immunotherapy of hematologic cancers

    D P Granados, A Rodenbrock, J-P Laverdure, C Côté, O Caron-Lizotte, C Carli, H Pearson, V Janelle, C Durette, E Bonneil , Denis-Claude Roy , Jean-Sébastien Delisle , S Lemieux, P Thibault, C Perreault
    DOI 10.1038/leu.2016.22 PMID 26857467
    Consulter
  • The Importance of Single-Mode Behavior in Silicon-On-Insulator Rib Waveguides With Very Large Cross Section for Resonant Sensing Applications

    Antoine Leblanc-Hotte , Jean-Sébastien Delisle , Sylvie Lesage , Yves-Alain Peter
    DOI 10.1109/JSTQE.2016.2545634
    Consulter
  • Favorable long-term outcome of patients with multiple myeloma using a frontline tandem approach with autologous and non-myeloablative allogeneic transplantation

    DOI 10.1038/bmt.2015.319 PMID 26691426
    Consulter
  • Defining novel parameters for the optimal priming and expansion of minor histocompatibility antigen-specific T cells in culture

    Valérie Janelle, Cédric Carli, Julie Taillefer, Julie Orio , Jean-Sébastien Delisle
    DOI 10.1186/s12967-015-0495-z PMID 25925868
    Consulter
  • Early exposure to interleukin-21 limits rapidly generated anti-Epstein-Barr virus T-cell line differentiation

    Julie Orio, Cédric Carli, Valérie Janelle , Martin Giroux , Julie Taillefer, Mathieu Goupil, Manon Richaud , Denis-Claude Roy , Jean-Sébastien Delisle
    DOI 10.1016/j.jcyt.2014.12.009 PMID 25661862
    Consulter
  • Harnessing the power of alloreactivity without triggering graft-versus-host disease: how non-engrafting alloreactive cellular therapy might change the landscape of acute myeloid leukemia treatment

    DOI 10.1016/j.blre.2014.08.002 PMID 25228333
    Consulter
  • Neuropilin-1 mediates myeloid cell chemoattraction and influences retinal neuroimmune crosstalk

    Agnieszka Dejda, Gaelle Mawambo, Agustin Cerani, Khalil Miloudi, Zhuo Shao, Jean-Francois Daudelin, Salix Boulet, Malika Oubaha, Felix Beaudoin, Naoufal Akla, Sullivan Henriques, Catherine Menard, Andreas Stahl , Jean-Sébastien Delisle , Flavio A Rezende, Nathalie Labrecque, Przemyslaw Sapieha
    DOI 10.1172/JCI76492 PMID 25271625
    Consulter
  • The TGF-β-Smad3 pathway inhibits CD28-dependent cell growth and proliferation of CD4 T cells

    Jean-Sébastien Delisle , Martin Giroux , G Boucher, J-R Landry, M-P Hardy, S Lemieux, R G Jones, B T Wilhelm, C Perreault
    DOI 10.1038/gene.2012.63 PMID 23328844
    Consulter
  • Immunoregulatory CD4(-)CD8(-) T cells as a potential therapeutic tool for transplantation, autoimmunity, and cancer

    DOI 10.3389/fimmu.2013.00006 PMID 23355840
    Consulter
  • Roles of transforming growth factor-β in graft-versus-host and graft-versus-tumor effects

    DOI 10.1016/j.bbmt.2012.01.020 PMID 22326303
    Consulter
  • T cell activation leads to protein kinase C theta-dependent inhibition of TGF-beta signaling

    Martin Giroux , Jean-Sébastien Delisle , Alan O'Brien, Marie-Josée Hébert, Claude Perreault
    DOI 10.4049/jimmunol.1000137 PMID 20592275
    Consulter
  • SMAD3 prevents graft-versus-host disease by restraining Th1 differentiation and granulocyte-mediated tissue damage

    Martin Giroux , Jean-Sébastien Delisle , Simon-David Gauthier, Krista M Heinonen, Julie Hinsinger, Billy Houde, Louis Gaboury, Sylvie Brochu, Jiangping Wu, Marie-Josée Hébert, Claude Perreault
    DOI 10.1182/blood-2010-05-287649 PMID 21119112
    Consulter
  • Graft-versus-host disease causes failure of donor hematopoiesis and lymphopoiesis in interferon-gamma receptor-deficient hosts

    Jean-Sébastien Delisle , Louis Gaboury, Marie-Pier Bélanger, Eliane Tassé, Hideo Yagita, Claude Perreault
    DOI 10.1182/blood-2007-12-130534 PMID 18552211
    Consulter
  • Immunothérapie anti-cancer sans dommages collatéraux

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