Passer au contenu principal
Centre intégré universitaire de santé
et de services sociaux de l'Est-de-l'Île-de-Montréal

Centre intégré universitaire de santé et de services sociaux de l'Est-de-l'Île-de-Montréal

Jean-Sébastien Delisle, M.D., Ph. D.

Jean-Sébastien Delisle

Hématologue-greffeur, Professeur titulaire

L'équipe de l’IHOT

Chercheur-clinicien

Contact

Tél. : 514 252-3404

Dr Jean-Sébastien Delisle consacre ses recherches à l’immunothérapie cellulaire et, plus précisément, à la biologie des lymphocytes T ainsi qu'à l’impact de leur différenciation et fonction dans le développement et l’évaluation d’immunothérapies cellulaires. 

 

  • Chercheur chevronné FRQS (2023-2027)
  • Coordonnateur médical du CETC (Centre d’excellence en thérapie cellulaire) HMR
  • Directeur de l'unité de recherche en Immunologie du cancer et transplantation du Centre de recherche HMR
  • Membre du Comité de priorisation clinique et recherche de l'IHOT
  • Membre du Comité de direction de l'IHOT
  • Directeur du Réseau de thérapie cellulaire, tissulaire et génique du Québec (ThéCell)
  • Chercheur associé de l’Institut de recherche en immunologie et en cancérologie (IRIC)
  • Entrée en poste à l’Hôpital Maisonneuve-Rosemont : 2010

 

Formation :

  • Doctorat en sciences biomédicales : Université de Montréal (Canada), 2004-2010
  • Résidences en médecine interne et hématologie : Université McGill, Montréal (Canada), 1999-2004
  • Doctorat en médecine : Université de Montréal (Canada), 1994-1999

Découvrez ses publications

  • Abstracts of the Cell Therapy Transplant Canada 2023 Annual Conference

    Stephanie A Maier , Imran Ahmad , Tobias Berg, Susan Berrigan, Mahmoud Elsawy, Alejandro Garcia-Horton, Wilson Lam, Alix Lapworth, Luciana Melo Garcia, Ravi M Shah, Ram Vasudevan Nampoothiri , Jean-Sébastien Delisle
    DOI 10.3390/curroncol31060223 PMID 38920707
    Consulter

  • Armstrong strain lymphocytic choriomeningitis virus infection after accidental laboratory exposure

    Laurence Caron , Jean-Sébastien Delisle , James E Strong, Yvon Deschambault, Félix Lombard-Vadnais, Annie-Claude Labbé , Sylvie Lesage
    DOI 10.1186/s12985-023-02258-x PMID 38087355
    Consulter

  • SARS-CoV-2 Variants Omicron BA.4/5 and XBB.1.5 Significantly Escape T Cell Recognition in Solid-organ Transplant Recipients Vaccinated Against the Ancestral Strain

    Torin Halvorson, Sabine Ivison, Qing Huang, Gale Ladua, Demitra M Yotis, Dhiraj Mannar, Sriram Subramaniam, Victor H Ferreira, Deepali Kumar, Sara Belga, Megan K Levings, PREVenT Study Group , Jean-Sébastien Delisle
    DOI 10.1097/TP.0000000000004873 PMID 38012843
    Consulter

  • Improved outcomes of UM171-expanded cord blood transplantation compared with other graft sources: real-world evidence

    Sandra Cohen , Nadia Bambace , Imran Ahmad , Jean Roy , Xiaoying Tang, Mei-Jie Zhang, Linda Burns, Frédéric Barabé , Léa Bernard , Jean-Sébastien Delisle , Thomas Kiss , Sylvie Lachance , Denis-Claude Roy , Olivier Veilleux , Guy Sauvageau
    DOI 10.1182/bloodadvances.2023010599 PMID 37467030
    Consulter

  • CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax

    Mathieu Neault, Charles-Étienne Lebert-Ghali, Marilaine Fournier, Caroline Capdevielle, Elizabeth A R Garfinkle, Alyssa Obermayer, Anitria Cotton, Karine Boulay , Christina Sawchyn, Sarah St-Amand, Kamy H Nguyen, Béatrice Assaf, François E Mercier , Jean-Sébastien Delisle , Elliot A Drobetsky, Laura Hulea, Timothy I Shaw, Johannes Zuber, Tanja A Gruber, Heather J Melichar, Frédérick A Mallette
    DOI 10.1016/j.celrep.2023.113084 PMID 37716355
    Consulter

  • Omicron BA.4/5 Neutralization and T-Cell Responses in Organ Transplant Recipients After Booster Messenger RNA Vaccine: A Multicenter Cohort Study

    Victor H Ferreira, Matthew Ierullo, Faranak Mavandadnejad, Alexandra Kurtesi, Queenie Hu, W Rod Hardy, Victoria G Hall, Natalia Pinzon, Demitra Yotis , Anne-Claude Gingras, Sara Belga, Sarah Shalhoub, Marie-Josée Hébert, Atul Humar, Dima Kabbani, Deepali Kumar , Jean-Sébastien Delisle
    DOI 10.1093/cid/ciad175 PMID 36975097
    Consulter

  • Immunogenicity, Safety, and Breakthrough Severe Acute Respiratory Syndrome Coronavirus 2 Infections After Coronavirus Disease 2019 Vaccination in Organ Transplant Recipients: A Prospective Multicenter Canadian Study

    Dima Kabbani,corresponding author Demitra M Yotis, Victor H Ferreira, Sarah Shalhoub, Sara Belga, Varalika Tyagi, Matthew Ierullo, Vathany Kulasingam, Marie-Josée Hébert, Lori West , Jean-Sébastien Delisle , Normand Racine, Sacha A De Serres, Héloïse Cardinal, Mélanie Dieudé, Atul Humar, Deepali Kumar
    DOI 10.1093/ofid/ofad200 PMID 37213422
    Consulter

  • Immature and mature bone marrow-derived dendritic cells exhibit distinct intracellular mechanical properties

    Antoine Leblanc-Hotte, Cindy Audiger, Geneviève Chabot-Roy, Félix Lombard-Vadnais , Jean-Sébastien Delisle , Yves-Alain Peter , Sylvie Lesage
    DOI 10.1038/s41598-023-28625-w PMID 36737470
    Consulter

  • Impact of Implementing a Bendamustine-Based Conditioning Regimen on Outcomes of Autologous Stem Cell Transplantation in Lymphoma while Novel Cellular Therapies Emerge

    Sylvie Lachance , Alex Bourguignon, Josie-Anne Boisjoly, Philippe Bouchard , Imran Ahmad , Nadia Bambace , Léa Bernard , Sandra Cohen , Jean-Sébastien Delisle , Isabelle Fleury , Thomas Kiss , Luigina Mollica , Denis-Claude Roy , Guy Sauvageau , Olivier Veilleux , Justine Zehr, Miguel Chagnon , Jean Roy
    DOI 10.1016/j.jtct.2022.10.003 PMID 36243319
    Consulter

  • Bortezomib Maintenance After Allogeneic Transplantation in Newly Diagnosed Myeloma Patients Results in Decreased Incidence and Severity of Chronic GVHD

    Jean-Sébastien Claveau , Richard LeBlanc , Imran Ahmad , Jean-Sébastien Delisle , Sandra Cohen , Thomas Kiss , Nadia Bambace , Léa Bernard , Sylvie Lachance , Denis-Claude Roy , Guy Sauvageau , Olivier Veilleux , Jean Roy
    DOI 10.1016/j.jtct.2022.10.022 PMID 36334654
    Consulter

  • Blasts in context: the impact of the immune environment on acute myeloid leukemia prognosis and treatment

    Yasmina Serroukh , Josée Hébert , Lambert Busque , François Mercier , Chris Rudd , Sarit Assouline , Sylvie Lachance , Jean-Sébastien Delisle
    DOI 10.1016/j.blre.2022.100991 PMID 35941029
    Consulter

  • Abstracts of the Cell Therapy Transplant Canada 2022 Annual Conference

    Stephanie A Maier, Tobias Berg, Susan Berrigan, Jonathan Bramson, Chris Bredeson, Guy Cantin, Andrew Daly, Gwynivere A Davies, Mahmoud Elsawy , Alejandro Garcia-Horton, Wilson Lam, Alix Lapworth, Kylie Lepic, Luciana Melo Garcia, Kirk R Schultz , Ram Vasudevan Nampoothiri, Darrell White , Jean-Sébastien Delisle
    DOI 10.3390/curroncol29120783 PMID 36547197
    Consulter

  • Safety and Immunogenicity After a Three-Dose SARS-CoV-2 Vaccine Schedule in Allogeneic Stem Cell Transplant Recipients

    Muneyoshi Kimura, Victor H Ferreira, Sagar Kothari, Ivan Pasic, Jonas I Mattsson, Vathany Kulasingam, Atul Humar, Allison Mah , Jean-Sébastien Delisle , Matthew Ierullo, Beata Majchrzak-Kita, Deepali Kumar, Seyed M Hosseini-Moghaddam
    DOI 10.1016/j.jtct.2022.07.024 PMID 35914727
    Consulter

  • Combined PD-L1 and TIM3 blockade improves expansion of fit human CD8+ antigen-specific T cells for adoptive immunotherapy

    Shirin Lak, Valérie Janelle, Anissa Djedid, Gabrielle Boudreau, Ann Brasey, Véronique Lisi, Ali Smaani, Cédric Carli , Lambert Busque , Vincent-Philippe Lavallée , Jean-Sébastien Delisle
    DOI 10.1016/j.omtm.2022.09.016 PMID 36320412
    Consulter

  • Donor Age and Non-Relapse Mortality: Study of Their Association after HLA-Matched Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndrome

    Yasmine Kadri, Michelle Phan, Nadia Bambace , Léa Bernard , Sandra Cohen , Jean-Sébastien Delisle , Thomas Kiss , Sylvie Lachance , Denis-Claude Roy , Guy Sauvageau , Olivier Veilleux , Jean Roy , Imran Ahmad
    DOI 10.3390/curroncol29080470 PMID 36005208
    Consulter

  • Addition of elotuzumab to lenalidomide and dexamethasone for patients with newly diagnosed, transplantation ineligible multiple myeloma (ELOQUENT-1): an open-label, multicentre, randomised, phase 3 trial

    Meletios A Dimopoulos, Paul G Richardson, Nizar J Bahlis, Sebastian Grosicki, Michele Cavo, Meral Beksaç, Wojciech Legieć, Anna M Liberati, Hartmut Goldschmidt , Andrew Belch, Hila Magen, Alessandra Larocca, Jacob P Laubach, Maria T Petrucci, Donna Reece, Darrell White, María-Victoria Mateos, Ivan Špička, Mihaela Lazaroiu , Jesús Berdeja, Jonathan L Kaufman, Ying-Ming Jou, Alex Ganetsky, Mihaela Popa McKiver, Sagar Lonial, Katja Weisel; ELOQUENT-1 investigators , Jean-Sébastien Delisle
    DOI 10.1016/S2352-3026(22)00103-X PMID 35550060
    Consulter

  • Real-World Outcomes of Autologous and Allogeneic Hematopoietic Stem Cell Transplantation for Relapsed/Refractory Hodgkin Lymphoma in the Era of Novel Therapies: A Canadian Perspective

    Olivier Veilleux , Jean-Sébastien Claveau , Habiba Alaoui , Jean Roy , Imran Ahmad , Jean-Sébastien Delisle , Thomas Kiss , Nadia M Bambace , Léa Bernard , Sandra Cohen , Guy Sauvageau , Isabelle Fleury , Luigina Mollica , Denis-Claude Roy , Yasmina Serroukh , Sylvie Lachance
    DOI 10.1016/j.jtct.2021.12.005 PMID 34954149
    Consulter

  • Early free light chain reduction following treatment initiation predicts favorable outcome in intact immunoglobulin myeloma

    Jean-Sébastien Claveau , Sophie Savary Bélanger , Imran Ahmad , Jean-Sébastien Delisle , Vincent De Guire , Jean Roy , Richard LeBlanc
    DOI 10.1038/s41408-021-00600-6 PMID 34987163
    Consulter

  • Outcomes in newly diagnosed young or high-risk myeloma patients receiving tandem autologous/allogeneic transplant followed by bortezomib maintenance: a phase II study

    Richard LeBlanc , Imran Ahmad , Rafik Terra, Jean-Samuel Boudreault, David Ogez, Kristopher Lamore , Jean-Sébastien Delisle , Nadia Bambace , Léa Bernard , Sandra Cohen , Thomas Kiss , Sylvie Lachance , Séverine Landais, Émilie Lemieux-Blanchard , Guy Sauvageau , Michael Sebag , Denis-Claude Roy , Jean Roy
    DOI 10.1038/s41409-021-01532-2 PMID 34845367
    Consulter

  • p16INK4a Regulates Cellular Senescence in PD-1-Expressing Human T Cells

    Valérie Janelle, Mathieu Neault, Marie-Ève Lebel, Dave Maurice De Sousa, Salix Boulet, Ludovic Durrieu, Cédric Carli, Chloé Muzac, Sébastien Lemieux, Nathalie Labrecque, Heather J Melichar, Frédérick A Mallette , Jean-Sébastien Delisle
    DOI 10.3389/fimmu.2021.698565 PMID 34434190
    Consulter

  • CD5 levels define functionally heterogeneous populations of naïve human CD4+ T cells

    Aditi Sood, Marie-Ève Lebel, Mengqi Dong, Marilaine Fournier, Suzanne J Vobecky, Élie Haddad , Jean-Sébastien Delisle , Judith N Mandl, Nienke Vrisekoop, Heather J Melichar
    DOI 10.1002/eji.202048788 PMID 33682083
    Consulter

  • Myeloid-resident neuropilin-1 promotes choroidal neovascularization while mitigating inflammation

    Elisabeth M M A Andriessen, François Binet, Frédérik Fournier, Masayuki Hata, Agnieszka Dejda, Gaëlle Mawambo, Sergio Crespo‐Garcia, Frédérique Pilon, Manuel Buscarlet, Karine Beauchemin, Véronique Bougie , Garth Cumberlidge, Ariel M Wilson, Steve Bourgault, Flavio A Rezende, Normand Beaulieu , Jean-Sébastien Delisle , Przemyslaw Sapieha
    DOI 10.15252/emmm.201911754 PMID 33876574
    Consulter

  • Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes

    Grégory Ehx, Jean-David Larouche, Chantal Durette, Jean-Philippe Laverdure, Leslie Hesnard, Krystel Vincent, Marie-Pierre Hardy, Catherine Thériault, Caroline Rulleau, Joël Lanoix, Eric Bonneil, Albert Feghaly, Anca Apavaloaei , Nandita Noronha, Céline M Laumont , Jean-Sébastien Delisle , Luca Vago , Josée Hébert , Guy Sauvageau , Sébastien Lemieux, Pierre Thibault, Claude Perreault
    DOI 10.1016/j.immuni.2021.03.001 PMID 33740418
    Consulter

  • UM171-Expanded Cord Blood Transplants Support Robust T Cell Reconstitution with Low Rates of Severe Infections

    Maude Dumont-Lagacé, Qi Li , Mégane Tanguay , Jalila Chagraoui, Tibila Kientega, Guillaume B Cardin, Ann Brasey, Assya Trofimov, Cédric Carli , Imran Ahmad , Nadia M Bambace , Léa Bernard , Thomas Kiss , Jean Roy , Denis-Claude Roy , Sébastien Lemieux, Claude Perreault, Francis Rodier, Simon Frédéric Dufresne , Lambert Busque , Sylvie Lachance , Guy Sauvageau , Sandra Cohen , Jean-Sébastien Delisle
    DOI 10.1016/j.bbmt.2020.09.031 PMID 33022376
    Consulter

  • Single UM171-expanded cord blood transplant can cure severe idiopathic aplastic anemia in absence of suitable donors

    Jean-Sébastien Claveau , Sandra Cohen , Imran Ahmad , Jean-Sébastien Delisle , Thomas Kiss , Sylvie Lachance , Guy Sauvageau , Lambert Busque , Rose-Marie Brito, Nadia Bambace , Léa Bernard , Denis-Claude Roy , Jean Roy
    DOI 10.1111/ejh.13504 PMID 32749758
    Consulter

  • Newly diagnosed multiple myeloma patients treated with tandem auto-allogeneic stem cell transplant have better overall survival with similar outcomes at time of relapse compared to patients who received autologous transplant only

    Richard LeBlanc , Jean-Sébastien Claveau , Imran Ahmad , Jean-Sébastien Delisle , Nadia M Bambace , Léa Bernard , Sandra Cohen , Thomas Kiss , Sylvie Lachance , Séverine Landais , Denis-Claude Roy , Guy Sauvageau , Jean Roy
    DOI 10.1111/ctr.14099 PMID 32981146
    Consulter

  • T-Cell Immunotherapies Targeting Histocompatibility and Tumor Antigens in Hematological Malignancies

    Valérie Janelle, Caroline Rulleau, Simon Del Testa, Cédric Carli , Jean-Sébastien Delisle
    DOI 10.3389/fimmu.2020.00276 PMID 32153583
    Consulter

  • Hematopoietic stem cell transplantation using single UM171-expanded cord blood: a single-arm, phase 1-2 safety and feasibility study

    Sandra Cohen , Jean Roy , Sylvie Lachance , Jean-Sébastien Delisle , Anne Marinier , Lambert Busque , Denis-Claude Roy , Imran Ahmad , Nadia M Bambace , Léa Bernard , Thomas Kiss , Philippe Bouchard, Pierre Caudrelier, Sévérine Landais, Fannie Larochelle, Jalila Chagraoui, Bernhard Lehnertz, Sophie Corneau, Elisa Tomellini, Jeroen J A van Kampen, Jan J Cornelissen, Maude Dumont-Lagacé, Mégane Tanguay, Qi Li , Sébastien Lemieux, Peter W Zandstra , Guy Sauvageau
    DOI 10.1016/S2352-3026(19)30202-9 PMID 31704264
    Consulter

  • Evaluation of the Impact of Autologous Hematopoietic Stem Cell Transplantation on the Quality of Life of Older Patients with Lymphoma

    Christopher Lemieux , Imran Ahmad , Nadia M. Bambace , Léa Bernard , Sandra Cohen , Jean-Sébastien Delisle , Isabelle Fleury , Thomas Kiss , Luigina Mollica , Denis-Claude Roy , Guy Sauvageau , Jean Roy , Sylvie Lachance
    DOI 10.1016/j.bbmt.2019.09.007 PMID 31521818
    Consulter

  • TGFβ Programs Central Memory Differentiation in Ex Vivo-Stimulated Human T Cells

    Amina Dahmani, Valérie Janelle, Cédric Carli, Manon Richaud, Caroline Lamarche, Myriam Khalili, Mathieu Goupil, Ksenia Bezverbnaya, Jonathan L Bramson , Jean-Sébastien Delisle
    DOI 10.1158/2326-6066.CIR-18-0691 PMID 31308016
    Consulter

  • Allodepleted T-cell immunotherapy after haploidentical haematopoietic stem cell transplantation without severe acute graft-versus-host disease (GVHD) in the absence of GVHD prophylaxis

    Denis-Claude Roy , Sylvie Lachance , Sandra Cohen , Jean-Sébastien Delisle , Thomas Kiss , Guy Sauvageau , Lambert Busque , Imran Ahmad , Léa Bernard , Nadia M Bambace, Radia S Boumédine, Marie-Claude Guertin, Katayoun Rezvani, Stephan Mielke, Claude Perreault , Jean Roy
    DOI 10.1111/bjh.15970 PMID 31135970
    Consulter

  • Outcome of autologous hematopoietic stem cell transplant in older patients with B cell lymphoma when selected for fitness and chemosensitive disease

    Christopher Lemieux , Imran Ahmad , Nadia M. Bambace , Léa Bernard , Sandra Cohen , Jean-Sébastien Delisle , Isabelle Fleury , Thomas Kiss , Luigina Mollica , Denis-Claude Roy , Guy Sauvageau , Jean Roy , Sylvie Lachance
    DOI 10.1016/j.leukres.2019.01.002 PMID 30654975
    Consulter

  • Leukoreduction system chambers are a reliable cellular source for the manufacturing of T-cell therapeutics

    Gabrielle Boudreau, Cédric Carli, Caroline Lamarche, Caroline Rulleau, Guillaume Bonnaure, Sonia Néron , Jean-Sébastien Delisle
    DOI 10.1111/trf.15121 PMID 30589447
    Consulter

  • On-chip refractive index cytometry for whole-cell deformability discrimination

    Antoine Leblanc-Hotte, Nadine Sen Nkwe, Geneviève Chabot-Roy, El Bachir Affar , Sylvie Lesage , Jean-Sébastien Delisle , Yves-Alain Peter
    DOI 10.1039/c8lc00938d PMID 30570636
    Consulter

  • Double-Negative T Cell Levels Correlate with Chronic Graft-versus-Host Disease Severity

    Erin E Hillhouse, Stéphanie Thiant, Moutuaata M Moutuou, Félix Lombard-Vadnais, Rachel Parat , Jean-Sébastien Delisle , Imran Ahmad , Denis-Claude Roy , Martin Guimond , Jean Roy , Sylvie Lesage
    DOI 10.1016/j.bbmt.2018.09.008 PMID 30244108
    Consulter

  • A standardized immune phenotyping and automated data analysis platform for multicenter biomarker studies

    Sabine Ivison, Mehrnoush Malek, Rosa V Garcia, Raewyn Broady, Anne Halpin, Manon Richaud, Rollin F Brant, Szu-I Wang, Mathieu Goupil, Qingdong Guan , Peter Ashton, Jason Warren, Amr Rajab, Simon Urschel, Deepali Kumar, Mathias Streitz, Birgit Sawitzki, Stephan Schlickeiser, Janetta J Bijl, Donna A Wall , Jean-Sébastien Delisle , Lori J West, Ryan R Brinkman, Megan K Levings
    DOI 10.1172/jci.insight.121867 PMID 30518691
    Consulter

  • TGF-β in T Cell Biology: Implications for Cancer Immunotherapy

    Amina Dahmani , Jean-Sébastien Delisle
    DOI 10.3390/cancers10060194 PMID 29891791
    Consulter

  • Clinical-Scale Rapid Autologous BK Virus-Specific T Cell Line Generation From Kidney Transplant Recipients With Active Viremia for Adoptive Immunotherapy

    Caroline Lamarche, Julie Orio, Victoria Georges-Tobar, Thomas Pincez, Mathieu Goupil, Amina Dahmani, Cedric Carli, Ann Brasey , Lambert Busque , Jean-Sébastien Delisle
    DOI 10.1097/TP.0000000000001698 PMID 28230645
    Consulter

  • Cerebral adenovirus endotheliitis presenting as posterior reversible encephalopathy syndrome after allogeneic stem cell transplantation

    Jean-Sébastien Claveau , Richard LeBlanc , Imran Ahmad , J Ferreira, A-A Pistono, Nadia M Bambace , Léa Bernard , Sandra Cohen , Jean-Sébastien Delisle , Thomas Kiss , Sylvie Lachance , Jean Roy
    DOI 10.1038/bmt.2017.154 PMID 28692025
    Consulter

  • Opportunities and challenges for the cellular immunotherapy sector: a global landscape of clinical trials

    Katherine Bonter, Zackariah Breckenridge , Sylvie Lachance , Jean-Sébastien Delisle , Tania Bubela
    DOI 10.2217/rme-2017-0031 PMID 28850001
    Consulter

  • More Haste, Less Speed: Could Public-Private Partnerships Advance Cellular Immunotherapies?

    Tania Bubela, Katherine Bonter , Sylvie Lachance , Jean-Sébastien Delisle , E Richard Gold
    DOI 10.3389/fmed.2017.00134 PMID 28861415
    Consulter

  • Do We Need Full Donor Chimerism? How Alloreactive Cell Therapies without Substantial Engraftment Might Treat Hematologic Cancers

    Elizabeth F Krakow, Hui-Sheng Ai, Brian Shaffer , Jean-Sébastien Delisle , Kai-Xun Hu, Anthony D Sung
    DOI 10.2174/1389450116666150304103849 PMID 25738297
    Consulter

  • VEGF Requires the Receptor NRP-1 To Inhibit Lipopolysaccharide-Dependent Dendritic Cell Maturation

    Nougboli A E Oussa, Amina Dahmani, Marie Gomis, Manon Richaud, Emil Andreev, Ali-Reza Navab-Daneshmand, Julie Taillefer, Cédric Carli, Salix Boulet, Laurent Sabbagh , Nathalie Labrecque, Przemyslaw Sapieha , Jean-Sébastien Delisle
    DOI 10.4049/jimmunol.1601116 PMID 27815442
    Consulter

  • BK Polyomavirus and the Transplanted Kidney: Immunopathology and Therapeutic Approaches

    Caroline Lamarche, Julie Orio, Suzon Collette, Lynne Senécal, Marie-Josée Hébert, Édith Renoult, Lee Anne Tibbles , Jean-Sébastien Delisle
    DOI 10.1097/TP.0000000000001333 PMID 27391196
    Consulter

  • Proteogenomic-based discovery of minor histocompatibility antigens with suitable features for immunotherapy of hematologic cancers

    D P Granados, A Rodenbrock, J-P Laverdure, C Côté, O Caron-Lizotte, C Carli, H Pearson, V Janelle, C Durette, E Bonneil , Denis-Claude Roy , Jean-Sébastien Delisle , S Lemieux, P Thibault, C Perreault
    DOI 10.1038/leu.2016.22 PMID 26857467
    Consulter

  • Favorable long-term outcome of patients with multiple myeloma using a frontline tandem approach with autologous and non-myeloablative allogeneic transplantation

    Imran Ahmad , Richard LeBlanc , Sandra Cohen , Sylvie Lachance , Thomas Kiss , Guy Sauvageau , Denis-Claude Roy , Lambert Busque , Jean-Sébastien Delisle , Nadia M Bambace , Léa Bernard , W Sabry , Jean Roy
    DOI 10.1038/bmt.2015.319 PMID 26691426
    Consulter

  • Defining novel parameters for the optimal priming and expansion of minor histocompatibility antigen-specific T cells in culture

    Valérie Janelle, Cédric Carli, Julie Taillefer, Julie Orio , Jean-Sébastien Delisle
    DOI 10.1186/s12967-015-0495-z PMID 25925868
    Consulter

  • Early exposure to interleukin-21 limits rapidly generated anti-Epstein-Barr virus T-cell line differentiation

    Julie Orio, Cédric Carli, Valérie Janelle , Martin Giroux , Julie Taillefer, Mathieu Goupil, Manon Richaud , Denis-Claude Roy , Jean-Sébastien Delisle
    DOI 10.1016/j.jcyt.2014.12.009 PMID 25661862
    Consulter

  • Harnessing the power of alloreactivity without triggering graft-versus-host disease: how non-engrafting alloreactive cellular therapy might change the landscape of acute myeloid leukemia treatment

    Elizabeth F Krakow , Julie Bergeron , Sylvie Lachance , Denis-Claude Roy , Jean-Sébastien Delisle
    DOI 10.1016/j.blre.2014.08.002 PMID 25228333
    Consulter

  • Neuropilin-1 mediates myeloid cell chemoattraction and influences retinal neuroimmune crosstalk

    Agnieszka Dejda, Gaelle Mawambo, Agustin Cerani, Khalil Miloudi, Zhuo Shao, Jean-Francois Daudelin, Salix Boulet, Malika Oubaha, Felix Beaudoin, Naoufal Akla, Sullivan Henriques, Catherine Menard, Andreas Stahl , Jean-Sébastien Delisle , Flavio A Rezende, Nathalie Labrecque, Przemyslaw Sapieha
    DOI 10.1172/JCI76492 PMID 25271625
    Consulter

  • The TGF-β-Smad3 pathway inhibits CD28-dependent cell growth and proliferation of CD4 T cells

    Jean-Sébastien Delisle , Martin Giroux , G Boucher, J-R Landry, M-P Hardy, S Lemieux, R G Jones, B T Wilhelm, C Perreault
    DOI 10.1038/gene.2012.63 PMID 23328844
    Consulter

  • Immunoregulatory CD4(-)CD8(-) T cells as a potential therapeutic tool for transplantation, autoimmunity, and cancer

    Erin E Hillhouse , Jean-Sébastien Delisle , Sylvie Lesage
    DOI 10.3389/fimmu.2013.00006 PMID 23355840
    Consulter

  • Roles of transforming growth factor-β in graft-versus-host and graft-versus-tumor effects

    Cédric Carli , Martin Giroux , Jean-Sébastien Delisle
    DOI 10.1016/j.bbmt.2012.01.020 PMID 22326303
    Consulter

  • T cell activation leads to protein kinase C theta-dependent inhibition of TGF-beta signaling

    Martin Giroux , Jean-Sébastien Delisle , Alan O'Brien, Marie-Josée Hébert, Claude Perreault
    DOI 10.4049/jimmunol.1000137 PMID 20592275
    Consulter

  • SMAD3 prevents graft-versus-host disease by restraining Th1 differentiation and granulocyte-mediated tissue damage

    Martin Giroux , Jean-Sébastien Delisle , Simon-David Gauthier, Krista M Heinonen, Julie Hinsinger, Billy Houde, Louis Gaboury, Sylvie Brochu, Jiangping Wu, Marie-Josée Hébert, Claude Perreault
    DOI 10.1182/blood-2010-05-287649 PMID 21119112
    Consulter

  • Graft-versus-host disease causes failure of donor hematopoiesis and lymphopoiesis in interferon-gamma receptor-deficient hosts

    Jean-Sébastien Delisle , Louis Gaboury, Marie-Pier Bélanger, Eliane Tassé, Hideo Yagita, Claude Perreault
    DOI 10.1182/blood-2007-12-130534 PMID 18552211
    Consulter

  • Immunothérapie anti-cancer sans dommages collatéraux

    Marie-Christine Meunier , Jean-Sébastien Delisle , Chantal Baron, Claude Perreault
    DOI 10.1051/medsci/20062210794 PMID 17026920
    Consulter

  • T cells targeted against a single minor histocompatibility antigen can cure solid tumors

    Marie-Christine Meunier , Jean-Sébastien Delisle , Julie Bergeron , Vincent Rineau, Chantal Baron, Claude Perreault
    DOI 10.1038/nm1311 PMID 16227989
    Consulter

  • Coexpression of rat glutathione S-transferase A3 and human cytidine deaminase by a bicistronic retroviral vector confers in vitro resistance to nitrogen mustards and cytosine arabinoside in murine fibroblasts

    S Létourneau, J S Palerme , Jean-Sébastien Delisle , C M Beauséjour, R L Momparler, D Cournoyer
    DOI 10.1038/sj.cgt.7700169 PMID 10830723
    Consulter