Passer au contenu principal
Centre intégré universitaire de santé
et de services sociaux de l'Est-de-l'Île-de-Montréal

Centre intégré universitaire de santé et de services sociaux de l'Est-de-l'Île-de-Montréal

Josée Hébert, M.D.

Josée Hébert

Hématologue, Professeure titulaire

L'équipe de l’IHOT

Chercheur-clinicien

Contact

Tél. : 514 252-3404

Site web de Leucegene

Dre Josée Hébert co-dirige le projet Leucegene, dont les objectifs sont d’identifier de nouveaux biomarqueurs et cibles thérapeutiques et de développer de nouvelles thérapies pour traiter la leucémie myéloïde aigüe.

 

  • Directrice de la Banque de cellules leucémiques du Québec (BCLQ)
  • Directrice scientifique de la plateforme de cytogénétique de la BCLQ
  • Directrice médicale du laboratoire de cytogénétique de HMR
  • Titulaire de la Chaire Industrielle-Alliance de recherche en leucémie de l'Université de Montréal
  • Membre du comité exécutif du Réseau de recherche sur le cancer, Fonds de recherche du Québec - Santé (FRQS)
  • Entrée en poste à l’Hôpital Maisonneuve-Rosemont : 2000

 

Formation :

  • Fellowship en génétique moléculaire des leucémies : Institut national de la santé et de la recherche médicale, Hôpital Saint-Louis de Paris (France), 1992-1994
  • Résidences en médecine interne et hématologie : Université de Montréal (Canada), 1986-1991
  • Doctorat en médecine : Université de Montréal (Canada), 1979-1984

Découvrez ses publications

  • Comparative small molecule screening of primary human acute leukemias, engineered human leukemia and leukemia cell lines

    Safia Safa-Tahar-Henni, Karla Páez Martinez, Verena Gress, Nayeli Esparza, Élodie Roques, Florence Bonnet-Magnaval, Mélanie Bilodeau, Valérie Gagné, Eva Bresson, Sophie Cardin, Nehme El-Hachem, Isabella Iasenza, Gabriel Alzial , Isabel Boivin, Naoto Nakamichi 8, Anne-Cécile Soufflet, Cristina Mirela Pascariu, Jean Duchaine, Simon Mathien, Éric Bonneil, Kolja Eppert, Anne Marinier , Guy Sauvageau , Geneviève Deblois, Pierre Thibault , Josée Hébert , Connie J Eaves, Sonia Cellot, Frédéric Barabé, Brian T Wilhelm
    DOI 10.1038/s41375-024-02400-w PMID 39472547
    Consulter

  • Integrated drug resistance and leukemic stemness gene-expression scores predict outcomes in large cohort of over 3500 AML patients from 10 trials

    Abdelrahman H. Elsayed, Xueyuan Cao, Richard J. Marrero, Nam H. K. Nguyen, Huiyun Wu, Yonhui Ni, Raul C. Ribeiro, Herold Tobias, Peter J. Valk, François Béliveau, Guillaume Richard-Carpentier, , Josée Hébert , C. Michel Zwaan, Alan Gamis, Edward Anders Kolb, Richard Aplenc, Todd A. Alonzo, Soheil Meshinchi, Jeffrey Rubnitz, Stanley Pounds, Jatinder K. Lamba
    DOI 10.1038/s41698-024-00643-5 PMID 39090192
    Consulter

  • Genetic deletion of JAM-C in pre-leukemic cells rewires leukemic stem cell gene expression program in AML

    Julien M.P. Grenier, Céline Testut, Matthieu Bal, Florence Bardin, Maria De Grandis, Véronique Gelsi-Boyer, Julien Vernerny, Marjorie C Delahaye, Samuel Granjeaud, Christophe Zemmour, Jean-François Spinella, Triantafyllos Chavakis, Stephane JC Mancini , Jean-Marie Boher , Josée Hébert , Guy Sauvageau , Norbert Vey, Juerg Schwaller, Marie-Anne Hospital, Cyril Fauriat, Michel A Aurrand-Lions
    DOI 10.1182/bloodadvances.2023011747 PMID 38954834
    Consulter

  • Immunotherapeutic targeting of surfaceome heterogeneity in AML

    Marie-Eve Bordeleau, Éric Audemard, Arnaud Métois, Louis Theret, Véronique Lisi, Azer Farah, Jean-François Spinella, Jalila Chagraoui, Ossama Moujaber, Léo Aubert, Banafsheh Khakipoor, Laure Mallinger, Isabel Boivin, Nadine Mayotte , Azadeh Hajmirza, Éric Bonneil, François Béliveau, Sybille Pfammatter, Albert Feghaly, Geneviève Boucher, Patrick Gendron, Pierre Thibault, Frédéric Barabé, Sébastien Lemieux, Guillaume Richard-Carpentier , Josée Hébert , Vincent-Philippe Lavallée, Philippe P Roux , Guy Sauvageau
    DOI 10.1016/j.celrep.2024.114260 PMID 38838225
    Consulter

  • SF3B1 mutations provide genetic vulnerability to copper ionophores in human acute myeloid leukemia

    Céline Moison, Deanne Gracias, Julie Schmitt, Simon Girard, Jean-François Spinella, Simon Fortier, Isabel Boivin, Rodrigo Mendoza-Sanchez, Bounkham Thavonekham , Tara MacRae, Nadine Mayotte, Eric Bonneil, Mark Wittman, James Carmichael, Réjean Ruel, Pierre Thibault , Josée Hébert , Anne Marinier , Guy Sauvageau
    DOI 10.1126/sciadv.adl4018 PMID 38517966
    Consulter

  • CBFA2T3::GLIS2 pediatric acute megakaryoblastic leukemia is sensitive to BCL-XL inhibition by navitoclax and DT2216

    Verena Gress, Mathieu Roussy, Luc Boulianne, Mélanie Bilodeau, Sophie Cardin, Nehme El-Hachem, Véronique Lisi, Banafsheh Khakipoor, Alexandre Rouette, Azer Farah, Louis Théret, Léo Aubert, Furat Fatima, Éric Audemard, Pierre Thibault, Éric Bonneil , Jalila Chagraoui, Louise Laramée, Patrick Gendron, Loubna Jouan, Safa Jammali, Bastien Paré, Shawn M. Simpson, Thai Hoa Tran, Michel Duval, Pierre Teira , Henrique Bittencourt, Raoul Santiago, Frédéric Barabé , Guy Sauvageau , Martin A. Smith , Josée Hébert , Philippe P. Roux, Tanja A. Gruber, Vincent-Philippe Lavallée, Brian T. Wilhelm, Sonia Cellot
    DOI 10.1182/bloodadvances.2022008899 PMID 37729615
    Consulter

  • GPRC5C drives branched-chain amino acid metabolism in leukemogenesis

    Yu Wei Zhang, Talia Velasco-Hernandez, Julian Mess, Maria-Eleni Lalioti, Mari Carmen Romero-Mulero, Nadine Obier, Nikolaos Karantzelis, Jasmin Rettkowski, Katharina Schönberger , Noémie Karabacz, Karin Jäcklein, Tatsuya Morishima, Juan Luis Trincado, Paola Romecin, Alba Martinez, Hitoshi Takizawa, Khalid Shoumariyeh, Simon Renders, Robert Zeiser, Heike L. Pahl, François Béliveau , Josée Hébert , Bernhard Lehnertz , Guy Sauvageau , Pablo Menendez, Nina Cabezas-Wallscheid
    DOI 10.1182/bloodadvances.2023010460 PMID 37639313
    Consulter

  • DELE1 haploinsufficiency causes resistance to mitochondrial stress-induced apoptosis in monosomy 5/del(5q) AML

    Jean-François Spinella, Jalila Chagraoui, Céline Moison, Vincent P. Lavallée, Isabel Boivin, Deanne Gracias, Sylvie Lavallée, Guillaume Richard Carpentier, François Beliveau , Josée Hébert , Guy Sauvageau
    DOI 10.1038/s41375-023-02107-4 PMID 38102204
    Consulter

  • Optical Genome Mapping Reveals the Complex Genetic Landscape of Myeloma

    Amélie Giguère, Isabelle Raymond-Bouchard, Vanessa Collin , Jean-Sébastien Claveau , Josée Hébert , Richard LeBlanc
    DOI 10.3390/cancers15194687 PMID 37835381
    Consulter

  • Heterogeneity in leukemia cells that escape drug-induced senescence-like state

    David Miller, Kyra Kerkhofs, Farnoosh Abbas-Aghababazadeh, Sahib Singh Madahar, Mark D. Minden , Josée Hébert , Benjamin Haibe-Kains, Mark A. Bayfield, Samuel Benchimol
    DOI 10.1038/s41419-023-06015-4 PMID 37543610
    Consulter

  • Blasts in context: the impact of the immune environment on acute myeloid leukemia prognosis and treatment

    Yasmina Serroukh , Josée Hébert , Lambert Busque , François Mercier , Chris Rudd , Sarit Assouline , Sylvie Lachance , Jean-Sébastien Delisle
    DOI 10.1016/j.blre.2022.100991 PMID 35941029
    Consulter

  • Unified gene expression signature of novel NPM1 exon 5 mutations in acute myeloid leukemia

    Véronique Lisi, Ève Blanchard, Michael Vladovsky, Éric Audemard, Albert Ferghaly, Sébastien Lemieux , Josée Hébert , Guy Sauvageau , Vincent-Philippe Lavallée
    DOI 10.1182/bloodadvances.2022007300 PMID 35849707
    Consulter

  • HMGA2 expression defines a subset of human AML with immature transcriptional signature and vulnerability to G2/M inhibition

    Céline Moison, Jean-François Spinella, Jalila Chagraoui, Vincent-Philippe Lavallée, Bernhard Lehnertz, Clarisse Thiollier, Isabel Boivin, Nadine Mayotte, Tara MacRae, Anne Marinier , Josée Hébert , Guy Sauvageau
    DOI 10.1182/bloodadvances.2021005828 PMID 35797243
    Consulter

  • CDK7/12/13 inhibition targets an oscillating leukemia stem cell network and synergizes with venetoclax in acute myeloid leukemia

    Lixiazi He, Christian Arnold, Judith Thoma, Christian Rohde, Maksim Kholmatov, Swati Garg, Cheng‐Chih Hsiao, Linda Viol, Kaiqing Zhang https://orcid.org/0000-0003-0213-6035, Rui Sun, Christina Schmidt, Maike Janssen, Tara MacRae, Karin Huber, , Josée Hébert , Guy Sauvageau , Christian Thiede , Julia Spratte, Herbert Fluhr, Gabriela Aust, Carsten Müller‐Tidow, Christof Niehrs, Gislene Pereira, Jörg Hamann, Motomu Tanaka , Judith B Zaugg, Caroline Pabst
    DOI 10.15252/emmm.202114990 PMID 35253392
    Consulter

  • Monoallelic Heb/Tcf12 Deletion Reduces the Requirement for NOTCH1 Hyperactivation in T-Cell Acute Lymphoblastic Leukemia

    Diogo F T Veiga, Mathieu Tremblay, Bastien Gerby, Sabine Herblot, André Haman, Patrick Gendron, Sébastien Lemieux, Juan Carlos Zúñiga-Pflücker , Josée Hébert , Joseph Paul Cohen, Trang Hoang
    DOI 10.3389/fimmu.2022.867443 PMID 35401501
    Consulter

  • Vesicular trafficking is a key determinant of the statin response in acute myeloid leukemia

    Jana Krosl, Marie-Eve Bordeleau, Céline Moison, Tara MacRae, Isabel Boivin, Nadine Mayotte, Deanne Gracias, Irène Baccelli, Vincent-Philippe Lavallée, Richard Bisaillon, Bernhard Lehnertz, Rodrigo Mendoza-Sanchez, Réjean Ruel, Thierry Bertomeu , Jasmin Coulombe-Huntington, Geneviève Boucher, Nandita Noronha, Caroline Pabst, Mike Tyers, Patrick Gendron, Sébastien Lemieux, Frédéric Barabé, Anne Marinier , Josée Hébert , Guy Sauvageau
    DOI 10.1182/bloodadvances.2021006047 PMID 34731885
    Consulter

  • Epigenetic changes in human model KMT2A leukemias highlight early events during leukemogenesis

    Thomas Milan, Magalie Celton, Karine Lagacé, Élodie Roques, Safia Safa-Tahar-Henni, Eva Bresson, Anne Bergeron , Josée Hébert , Soheil Meshinchi , Sonia Cellot, Frédéric Barabé, Brian T Wilhelm
    DOI 10.3324/haematol.2020.271619 PMID 33375773
    Consulter

  • Legal and Ethical Considerations for the Design and Use of Web Portals for Researchers, Clinicians, and Patients: Scoping Literature Review

    Michael Lang, Sébastien Lemieux , Josée Hébert , Guy Sauvageau , Ma'n H Zawati
    DOI 10.2196/26450 PMID 34762055
    Consulter

  • Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes

    Grégory Ehx, Jean-David Larouche, Chantal Durette, Jean-Philippe Laverdure, Leslie Hesnard, Krystel Vincent, Marie-Pierre Hardy, Catherine Thériault, Caroline Rulleau, Joël Lanoix, Eric Bonneil, Albert Feghaly, Anca Apavaloaei , Nandita Noronha, Céline M Laumont , Jean-Sébastien Delisle , Luca Vago , Josée Hébert , Guy Sauvageau , Sébastien Lemieux, Pierre Thibault, Claude Perreault
    DOI 10.1016/j.immuni.2021.03.001 PMID 33740418
    Consulter

  • Human pluripotent stem cells identify molecular targets of trisomy 12 in chronic lymphocytic leukemia patients

    Jennifer C Reid, Diana Golubeva, Allison L Boyd, Cameron G Hollands, Charisa Henly, Luca Orlando, Andrew Leber , Josée Hébert , Fortunato Morabito, Giovanna Cutrona, Luca Agnelli, Massimo Gentile, Manlio Ferrarini, Antonino Neri, Brian Leber, Mickie Bhatia
    DOI 10.1016/j.celrep.2021.108845 PMID 33730576
    Consulter

  • Apoptotic Blocks in Primary Non-Hodgkin B Cell Lymphomas Identified by BH3 Profiling

    Ryan N Rys, Claudia M Wever, Dominique Geoffrion, Christophe Goncalves, Artin Ghassemian, Eugene Brailovski, Jeremy Ryan, Liliana Stoica , Josée Hébert , Tina Petrogiannis-Haliotis, Svetlana Dmitrienko, Saul Frenkiel, Annette Staiger, German Ott, Christian Steidl, David W Scott, Pierre Sesques, Sonia Del Rincon, Koren K Mann, Anthony Letai, Nathalie A Johnson
    DOI 10.3390/cancers13051002 PMID 33670870
    Consulter

  • Erratum: The uracil-DNA glycosylase UNG protects the fitness of normal and cancer B cells expressing AID

    Shiva Safavi, Ariane Larouche, Astrid Zahn, Anne-Marie Patenaude, Diana Domanska, Kiersten Dionne, Torbjørn Rognes, Felix Dingler, Seong-Kwi Kang, Yan Liu, Nathalie Johnson , Josée Hébert , Ramiro E Verdun, Cristina A Rada, Francisco Vega, Hilde Nilsen, Javier M D Noia
    DOI 10.1093/narcan/zcaa045 PMID 34316697
    Consulter

  • The uracil-DNA glycosylase UNG protects the fitness of normal and cancer B cells expressing AID

    Shiva Safavi, Ariane Larouche, Astrid Zahn, Anne-Marie Patenaude, Diana Domanska, Kiersten Dionne, Torbjørn Rognes, Felix Dingler, Seong-Kwi Kang, Yan Liu, Nathalie Johnson , Josée Hébert , Ramiro E Verdun, Cristina A Rada, Francisco Vega, Hilde Nilsen, Javier M Di Noia
    DOI 10.1093/narcan/zcaa019 PMID 33554121
    Consulter

  • High frequency of germline RUNX1 mutations in patients with RUNX1-mutated AML

    Laura Simon, Jean-François Spinella, Chi-Yuan Yao, Vincent-Philippe Lavallée, Isabel Boivin, Geneviève Boucher, Eric Audemard, Marie-Eve Bordeleau, Sébastien Lemieux , Josée Hébert , Guy Sauvageau
    DOI 10.1182/blood.2019003357 PMID 32315381
    Consulter

  • Cryptic recurrent ACIN1-NUTM1 fusions in non-KMT2A-rearranged infant acute lymphoblastic leukemia

    Thomas Pincez, Josette-Renée Landry, Mathieu Roussy, Loubna Jouan, Mélanie Bilodeau, Louise Laramée, Françoise Couture, Daniel Sinnett, Patrick Gendron , Josée Hébert , Luc Oligny, Alexandre Rouette, Thai H Tran, Brian T Wilhelm, Henrique Bittencourt, Sonia Cellot
    DOI 10.1002/gcc.22808 PMID 31515871
    Consulter

  • Genetic characterization of ABT-199 sensitivity in human AML

    Richard Bisaillon, Céline Moison, Clarisse Thiollier, Jana Krosl, Marie-Eve Bordeleau, Bernhard Lehnertz, Vincent-Philippe Lavallée, Tara MacRae, Nadine Mayotte , Caroline Labelle, Geneviève Boucher, Jean-François Spinella, Isabel Boivin, Giovanni D'Angelo, Sylvie Lavallée, Anne Marinier, Sébastien Lemieux , Josée Hébert , Guy Sauvageau
    DOI 10.1038/s41375-019-0485-x PMID 31300747
    Consulter

  • Cost-Effectiveness Analysis of a HMGA2 Prognostic Test for Acute Myeloid Leukemia in a Canadian Setting

    Gabriel Tremblay, Ben Rousseau, Miriam Marquis, Cyrielle Beaubois , Guy Sauvageau , Josée Hébert
    DOI 10.1007/s40258-019-00503-5 PMID 31392669
    Consulter

  • The neuropeptide receptor calcitonin receptor-like (CALCRL) is a potential therapeutic target in acute myeloid leukemia

    Linus Angenendt, Eike Bormann, Caroline Pabst, Vijay Alla, Dennis Görlich, Leonie Braun, Kim Dohlich, Christian Schwöppe, Stefan K. Bohlander, Maria Francisca Arteaga, Klaus Wethmar, Wolfgang Hartmann , Adrian Angenendt, Torsten Kessler, Rolf M. Mesters, Matthias Stelljes, Maja Rothenberg-Thurley, Karsten Spiekermann , Josée Hébert , Guy Sauvageau , Peter J. M. Valk, Bob Löwenberg, Hubert Serve, Carsten Müller-Tidow, Georg Lenz, Bernhard J. Wörmann, M. Christina Sauerland, Wolfgang Hiddemann , Wolfgang E. Berdel, Utz Krug, Klaus H. Metzeler, Jan-Henrik Mikesch, Tobias Herold, Christoph Schliemann
    DOI 10.1038/s41375-019-0505-x PMID 31182782
    Consulter

  • Human models of NUP98-KDM5A megakaryocytic leukemia in mice contribute to uncovering new biomarkers and therapeutic vulnerabilities

    Sophie Cardin, Mélanie Bilodeau, Mathieu Roussy, Léo Aubert, Thomas Milan, Loubna Jouan, Alexandre Rouette, Louise Laramée, Patrick Gendron, Jean Duchaine, Hélène Decaluwe, Jean-François Spinella, Stéphanie Mourad, Françoise Couture, Daniel Sinnett , Élie Haddad, Josette-Renée Landry, Jing Ma, R. Keith Humphries, Philippe P. Roux , Josée Hébert , Tanja A. Gruber, Brian T. Wilhelm, Sonia Cellot
    DOI 10.1182/bloodadvances.2019030981 PMID 31698461
    Consulter

  • Targeted variant detection using unaligned RNA-Seq reads

    Eric Olivier Audemard, Patrick Gendron, Albert Feghaly, Vincent-Philippe Lavallée , Josée Hébert , Guy Sauvageau , Sébastien Lemieux
    DOI 10.26508/lsa.201900336 PMID 31427380
    Consulter

  • IDH1 as a Cooperating Mutation in AML Arising in the Context of Shwachman-Diamond Syndrome

    Stéphanie Mourad, Mélanie Bilodeau, Mathieu Roussy, Louise Laramée, Luc Boulianne, Alexandre Rouette, Loubna Jouan, Patrick Gendron, Michel Duval, Pierre Teira , Josée Hébert , Henrique Bittencourt, Yves Pastore, Josette-Renée Landry, Sonia Cellot
    DOI 10.3389/fonc.2019.00772 PMID 31475115
    Consulter

  • Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A, NPM1, and FLT3-ITD triple-mutated AML

    Swati Garg, Armando Reyes-Palomares, Lixiazi He, Anne Bergeron, Vincent-Philippe Lavallée, Sébastien Lemieux, Patrick Gendron, Christian Rohde, Jianglong Xia, Prarabdha Jagdhane, Carsten Müller-Tidow, Daniel B. Lipka, Suzan Imren, R. Keith Humphries , Claudia Waskow, Binje Vick, Irmela Jeremias, Guillaume Richard-Carpentier , Josée Hébert , Guy Sauvageau , Judith B. Zaugg, Frédéric Barabé, Caroline Pabst
    DOI 10.1182/blood.2018862383 PMID 31076446
    Consulter

  • Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia

    Irène Baccelli, Yves Gareau, Bernhard Lehnertz, Stéphane Gingras, Jean-François Spinella, Sophie Corneau, Nadine Mayotte, Simon Girard, Mélanie Frechette, Valérie Blouin-Chagnon, Koryne Leveillé, Isabel Boivin, Tara MacRae, Jana Krosl , Clarisse Thiollier, Vincent-Philippe Lavallée, Evgeny Kanshin, Thierry Bertomeu, Jasmin Coulombe-Huntington, Corinne St-Denis, Marie-Eve Bordeleau, Geneviève Boucher , Philippe P Roux, Sébastien Lemieux, Mike Tyers, Pierre Thibault , Josée Hébert , Anne Marinier , Guy Sauvageau
    DOI 10.1016/j.ccell.2019.06.003 PMID 31287994
    Consulter

  • Complex karyotype AML displays G2/M signature and hypersensitivity to PLK1 inhibition

    Céline Moison, Vincent-Philippe Lavallée, Clarisse Thiollier, Bernhard Lehnertz, Isabel Boivin, Nadine Mayotte, Yves Gareau, Mélanie Fréchette, Valérie Blouin-Chagnon , Sophie Corneau, Sylvie Lavallée, Sébastien Lemieux, Anne Marinier , Josée Hébert , Guy Sauvageau
    DOI 10.1182/bloodadvances.2018028480 PMID 30782614
    Consulter

  • The Adhesion G Protein-Coupled Receptor GPR97/ ADGRG3 Is Expressed in Human Granulocytes and Triggers Antimicrobial Effector Functions

    Cheng-Chih Hsiao, Tai-Ying Chu, Chia-Jung Wu, Maartje van den Biggelaar, Caroline Pabst , Josée Hébert , Taco W Kuijpers, Brendon P Scicluna, Kuan-Yu I, Tse-Ching Chen, Ines Liebscher, Jörg Hamann, Hsi-Hsien Lin
    DOI 10.3389/fimmu.2018.02830 PMID 30559745
    Consulter

  • The genomic landscape of two Burkitt lymphoma cases and derived cell lines: comparison between primary and relapse samples

    Claudia M Wever, Dominique Geoffrion, Bruno M Grande, Stephen Yu, Miguel Alcaide, Maryse Lemaire, Yasser Riazalhosseini , Josée Hébert , Christina Gavino, Donald C Vinh, Tina Petrogiannis-Haliotis, Svetlana Dmitrienko, Koren K Mann, Ryan D Morin, Nathalie A Johnson
    DOI 10.1080/10428194.2017.1413186 PMID 29295643
    Consulter

  • High expression of HMGA2 independently predicts poor clinical outcomes in acute myeloid leukemia

    Miriam Marquis, Cyrielle Beaubois, Vincent-Philippe Lavallée, Michal Abrahamowicz, Coraline Danieli, Sébastien Lemieux , Imran Ahmad , Andrew Wei, Stephen B. Ting, Shaun Fleming, Anthony Schwarer, David Grimwade, William Grey, Robert K. Hills, Paresh Vyas, Nigel Russell , Guy Sauvageau , Josée Hébert
    DOI 10.1038/s41408-018-0103-6 PMID 30061630
    Consulter

  • Transcriptomic landscape of acute promyelocytic leukemia reveals aberrant surface expression of the platelet aggregation agonist Podoplanin

    Vincent-Philippe Lavallée, Jalila Chagraoui, Tara MacRae, Miriam Marquis, Arnaud Bonnefoy, Jana Krosl, Sébastien Lemieux, Anne Marinier, Caroline Pabst, Georges-Étienne Rivard , Josée Hébert , Guy Sauvageau
    DOI 10.1038/s41375-018-0069-1 PMID 29550835
    Consulter

  • GFI1 facilitates efficient DNA repair by regulating PRMT1 dependent methylation of MRE11 and 53BP1

    Charles Vadnais, Riyan Chen, Jennifer Fraszczak, Zhenbao Yu, Jonathan Boulais, Jordan Pinder, Daria Frank, Cyrus Khandanpour , Josée Hébert , Graham Dellaire, Jean-François Côté, Stéphane Richard, Alexandre Orthwein, Elliot Drobetsky, Tarik Möröy
    DOI 10.1038/s41467-018-03817-5 PMID 29651020
    Consulter

  • MEF2C Phosphorylation Is Required for Chemotherapy Resistance in Acute Myeloid Leukemia

    Fiona C Brown, Eric Still, Richard P Koche, Christina Y Yim, Sumiko Takao, Paolo Cifani, Casie Reed, Shehana Gunasekera, Scott B Ficarro, Peter Romanienko, Willie Mark , Craig McCarthy, Elisa de Stanchina, Mithat Gonen, Venkatraman Seshan, Patrick Bhola, Conor O'Donnell, Barbara Spitzer, Crystal Stutzke, Vincent-Philippe Lavallée , Josée Hébert , Andrei V Krivtsov, Ari Melnick, Elisabeth M Paietta, Martin S Tallman, Anthony Letai , Guy Sauvageau , Gayle Pouliot, Ross Levine, Jarrod A Marto, Scott A Armstrong, Alex Kentsis
    DOI 10.1158/2159-8290.CD-17-1271 PMID 29431698
    Consulter

  • NUP98-BPTF gene fusion identified in primary refractory acute megakaryoblastic leukemia of infancy

    Mathieu Roussy, Mélanie Bilodeau, Loubna Jouan, Pauline Tibout, Louise Laramée, Emmanuelle Lemyre, France Léveillé, Frédérique Tihy, Sophie Cardin, Camille Sauvageau, Françoise Couture, Isabelle Louis , Aurélien Choblet, Natalie Patey, Patrick Gendron, Michel Duval, Pierre Teira , Josée Hébert , Brian T. Wilhelm, John K. Choi, Tanja A. Gruber, Henrique Bittencourt, Sonia Cellot
    DOI 10.1002/gcc.22532 PMID 29427526
    Consulter

  • Identification of novel biomarkers for MLL-translocated acute myeloid leukemia

    Karine Lagacé, Fréderic Barabé , Josée Hébert , Sonia Cellot, Brian T Wilhelm
    DOI 10.1016/j.exphem.2017.08.006 PMID 28911906
    Consulter

  • H3K27M/I mutations promote context-dependent transformation in acute myeloid leukemia with RUNX1 alterations

    Bernhard Lehnertz, Yu Wei Zhang, Isabel Boivin, Nadine Mayotte, Elisa Tomellini, Jalila Chagraoui, Vincent-Philippe Lavallée , Josée Hébert , Guy Sauvageau
    DOI 10.1182/blood-2017-03-774653 PMID 28855157
    Consulter

  • Chemogenomic Landscape of RUNX1-mutated AML Reveals Importance of RUNX1 Allele Dosage in Genetics and Glucocorticoid Sensitivity

    Laura Simon, Vincent-Philippe Lavallée, Marie-Eve Bordeleau, Jana Krosl, Irène Baccelli, Geneviève Boucher, Bernhard Lehnertz, Jalila Chagraoui, Tara MacRae, Réjean Ruel , Yves Chantigny, Sébastien Lemieux, Anne Marinier , Josée Hébert , Guy Sauvageau
    DOI 10.1158/1078-0432.CCR-17-1259 PMID 28855357
    Consulter

  • MiSTIC, an integrated platform for the analysis of heterogeneity in large tumour transcriptome datasets

    Sebastien Lemieux, Tobias Sargeant, David Laperrière, Houssam Ismail, Geneviève Boucher, Marieke Rozendaal, Vincent-Philippe Lavallée, Dariel Ashton-Beaucage, Brian Wilhelm , Josée Hébert , Douglas J Hilton, Sylvie Mader , Guy Sauvageau
    DOI 10.1093/nar/gkx338 PMID 28472340
    Consulter

  • AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia

    Fengbiao Zhou, Yi Liu, Christian Rohde, Cornelius Pauli, Dennis Gerloff, Marcel Köhn, Danny Misiak, Nicole Bäumer, Chunhong Cui, Stefanie Göllner, Thomas Oellerich, Hubert Serve, Maria-Paz Garcia-Cuellar, Robert Slany , Jaroslaw P. Maciejewski, Bartlomiej Przychodzen, Barbara Seliger, Hans-Ulrich Klein, Christoph Bartenhagen, Wolfgang E. Berdel, Martin Dugas, Makoto Mark Taketo, Daneyal Farouq, Schraga Schwartz, Aviv Regev , Josée Hébert , Guy Sauvageau , Caroline Pabst, Stefan Hüttelmaier, Carsten Müller-Tidow
    DOI 10.1038/ncb3563 PMID 28650479
    Consulter

  • Adhesion GPCRs in Regulating Immune Responses and Inflammation

    Hsi-Hsien Lin, Cheng-Chih Hsiao, Caroline Pabst , Josée Hébert , Torsten Schöneberg, Jörg Hamann
    DOI 10.1016/bs.ai.2017.05.005 PMID 28950945
    Consulter

  • Modeling human MLL-AF9 translocated acute myeloid leukemia from single donors reveals RET as a potential therapeutic target

    F Barabé, L Gil, M Celton, A Bergeron, V Lamontagne, É Roques, K Lagacé, A Forest, R Johnson, L Pécheux, J Simard, J Pelloux, A Bellemare-Pelletier, E Gagnon , Josée Hébert , S Cellot, B T Wilhelm
    DOI 10.1038/leu.2016.302 PMID 27780967
    Consulter

  • A novel approach for the identification of efficient combination therapies in primary human acute myeloid leukemia specimens

    I Baccelli, J Krosl, G Boucher, I Boivin, V-P Lavallée , Josée Hébert , S Lemieux, A Marinier , Guy Sauvageau
    DOI 10.1038/bcj.2017.10 PMID 28211886
    Consulter

  • High-throughput screening in niche-based assay identifies compounds to target preleukemic stem cells

    Bastien Gerby, Diogo F T Veiga, Jana Krosl, Sami Nourreddine, Julianne Ouellette, André Haman, Geneviève Lavoie, Iman Fares, Mathieu Tremblay, Véronique Litalien, Elizabeth Ottoni, Milena Kosic , Dominique Geoffrion, Joël Ryan, Paul S Maddox, Jalila Chagraoui, Anne Marinier , Josée Hébert , Guy Sauvageau , Benjamin H Kwok, Philippe P Roux, Trang Hoang
    DOI 10.1172/JCI86489 PMID 27797342
    Consulter

  • Expression of immunoproteasome genes is regulated by cell-intrinsic and -extrinsic factors in human cancers

    Alexandre Rouette, Assya Trofimov, David Haberl, Geneviève Boucher, Vincent-Philippe Lavallée, Giovanni D'Angelo , Josée Hébert , Guy Sauvageau , Sébastien Lemieux, Claude Perreault
    DOI 10.1038/srep34019 PMID 27659694
    Consulter

  • Identification of MYC mutations in acute myeloid leukemias with NUP98-NSD1 translocations

    V-P Lavallée, S Lemieux, G Boucher, P Gendron, I Boivin, S Girard , Josée Hébert , Guy Sauvageau
    DOI 10.1038/leu.2016.19 PMID 26859078
    Consulter

  • Dynamic Bcl-xL (S49) and (S62) Phosphorylation/Dephosphorylation during Mitosis Prevents Chromosome Instability and Aneuploidy in Normal Human Diploid Fibroblasts

    Prasamit Saurav Baruah, Myriam Beauchemin , Josée Hébert , Richard Bertrand
    DOI 10.1371/journal.pone.0159091 PMID 27398719
    Consulter

  • Chemo-genomic interrogation of CEBPA mutated AML reveals recurrent CSF3R mutations and subgroup sensitivity to JAK inhibitors

    Vincent-Philippe Lavallée, Jana Krosl, Sébastien Lemieux, Geneviève Boucher, Patrick Gendron, Caroline Pabst, Isabel Boivin, Anne Marinier, Cynthia J. Guidos, Sylvain Meloche , Josée Hébert , Guy Sauvageau
    DOI 10.1182/blood-2016-03-705053 PMID 27034432
    Consulter

  • Transcriptome analysis of G protein-coupled receptors in distinct genetic subgroups of acute myeloid leukemia: identification of potential disease-specific targets

    A Maiga, S Lemieux, C Pabst, V-P Lavallée, M Bouvier , Guy Sauvageau , Josée Hébert
    DOI 10.1038/bcj.2016.36 PMID 27258612
    Consulter

  • RNA-sequencing analysis of core binding factor AML identifies recurrent ZBTB7A mutations and defines RUNX1-CBFA2T3 fusion signature

    Vincent-Philippe Lavallée, Sébastien Lemieux, Geneviève Boucher, Patrick Gendron, Isabel Boivin, Richard N. Armstrong , Guy Sauvageau , Josée Hébert
    DOI 10.1182/blood-2016-03-703868 PMID 26968532
    Consulter

  • GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo

    Caroline Pabst, Anne Bergeron, Vincent-Philippe Lavallée, Jonathan Yeh, Patrick Gendron, Gudmundur L. Norddahl, Jana Krosl, Isabel Boivin , Eric Deneault, Jessica Simard, Suzan Imren, Geneviève Boucher, Kolja Eppert, Tobias Herold, Stefan K. Bohlander, Keith Humphries, Sébastien Lemieux , Josée Hébert , Guy Sauvageau , Frédéric Barabé
    DOI 10.1182/blood-2015-11-683649 PMID 26834243
    Consulter

  • UTX inhibition as selective epigenetic therapy against TAL1-driven T-cell acute lymphoblastic leukemia

    Aissa Benyoucef, Carmen G Palii, Chaochen Wang, Christopher J Porter, Alphonse Chu, Fengtao Dai, Véronique Tremblay, Patricia Rakopoulos, Kulwant Singh, Suming Huang, Francoise Pflumio , Josée Hébert , Jean-Francois Couture, Theodore J Perkins, Kai Ge, F Jeffrey Dilworth, Marjorie Brand
    DOI 10.1101/gad.276790.115 PMID 26944678
    Consulter

  • Disclosure of incidental findings in cancer genomic research: investigators' perceptions on obligations and barriers

    E Kleiderman, D Avard, A Besso, S Ali-Khan , Guy Sauvageau , Josée Hébert
    DOI 10.1111/cge.12540 PMID 25492269
    Consulter

  • The transcriptomic landscape and directed chemical interrogation of MLL-rearranged acute myeloid leukemias

    Vincent-Philippe Lavallée, Irène Baccelli, Jana Krosl, Brian Wilhelm, Frédéric Barabé, Patrick Gendron, Geneviève Boucher, Sébastien Lemieux, Anne Marinier, Sylvain Meloche , Josée Hébert , Guy Sauvageau
    DOI 10.1038/ng.3371 PMID 26237430
    Consulter

  • EVI1-rearranged acute myeloid leukemias are characterized by distinct molecular alterations

    Vincent-Philippe Lavallée, Patrick Gendron, Sébastien Lemieux, Giovanni D’Angelo , Josée Hébert , Guy Sauvageau
    DOI 10.1182/blood-2014-07-591529 PMID 25331116
    Consulter

  • SCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cells

    Bastien Gerby, Cedric S Tremblay, Mathieu Tremblay, Shanti Rojas-Sutterlin, Sabine Herblot , Josée Hébert , Guy Sauvageau , Sébastien Lemieux, Eric Lécuyer, Diogo F T Veiga, Trang Hoang
    DOI 10.1371/journal.pgen.1004768 PMID 25522233
    Consulter

  • UBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activity

    Marie-Eve Bordeleau, Romain Aucagne, Jalila Chagraoui, Simon Girard, Nadine Mayotte, Éric Bonneil, Pierre Thibault, Caroline Pabst, Anne Bergeron, Frédéric Barabé , Josée Hébert , Martin Sauvageau, Christel Boutonnet, Sylvain Meloche , Guy Sauvageau
    DOI 10.1182/blood-2014-01-548651 PMID 25185265
    Consulter

  • Epigenetic regulation of GATA2 and its impact on normal karyotype acute myeloid leukemia

    M Celton, A Forest, G Gosse, S Lemieux , Josée Hébert , Guy Sauvageau , B T Wilhelm
    DOI 10.1038/leu.2014.67 PMID 24514424
    Consulter

  • Identification of small molecules that support human leukemia stem cell activity ex vivo

    Caroline Pabst, Jana Krosl, Iman Fares, Geneviève Boucher, Réjean Ruel, Anne Marinier, Sébastien Lemieux , Josée Hébert , Guy Sauvageau
    DOI 10.1038/nmeth.2847 PMID 24562423
    Consulter

  • Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance

    Manuel Buscarlet, Veneta Krasteva, Lena Ho, Camille Simon , Josée Hébert , Brian Wilhelm, Gerald R Crabtree , Guy Sauvageau , Pierre Thibault, Julie A Lessard
    DOI 10.1182/blood-2013-02-483495 PMID 24478402
    Consulter

  • The methyltransferase G9a regulates HoxA9-dependent transcription in AML

    Bernhard Lehnertz, Caroline Pabst, Le Su, Michelle Miller, Feng Liu, Lin Yi, Regan Zhang, Jana Krosl, Eric Yung, Jeanette Kirschner, Patty Rosten, T Michael Underhill, Jian Jin , Josée Hébert , Guy Sauvageau , R Keith Humphries, Fabio M Rossi
    DOI 10.1101/gad.236794.113 PMID 24532712
    Consulter

  • Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair

    Helen Yu, Helen Pak, Ian Hammond-Martel, Mehdi Ghram, Amélie Rodrigue, Salima Daou, Haithem Barbour, Luc Corbeil , Josée Hébert , Elliot Drobetsky, Jean Yves Masson, Javier M Di Noia, El Bachir Affar
    DOI 10.1073/pnas.1309085110 PMID 24347639
    Consulter

  • Funding considerations for the disclosure of genetic incidental findings in biobank research

    L Black, D Avard, M H Zawati, B M Knoppers , Josée Hébert , Guy Sauvageau , Leucegene Project
    DOI 10.1111/cge.12190 PMID 23662709
    Consulter

  • Identification of a novel fusion gene involving RUNX1 and the antisense strand of SV2B in a BCR-ABL1-positive acute leukemia

    Amélie Giguère , Josée Hébert
    DOI 10.1002/gcc.22105 PMID 24123676
    Consulter

  • RNA-Seq reveals spliceosome and proteasome genes as most consistent transcripts in human cancer cells

    Tara Macrae, Tobias Sargeant, Sébastien Lemieux , Josée Hébert , Eric Deneault , Guy Sauvageau
    DOI 10.1371/journal.pone.0072884 PMID 24069164
    Consulter

  • Nuclear remodeling of telomeres in chronic myeloid leukemia

    Oumar Samassekou , Josée Hébert , Sabine Mai, Ju Yan
    DOI 10.1002/gcc.22046 PMID 23341124
    Consulter

  • Presence of alternative lengthening of telomeres associated circular extrachromosome telomere repeats in primary leukemia cells of chronic myeloid leukemia

    Oumar Samassekou, Abba Malina , Josée Hébert , Ju Yan
    DOI 10.1186/1756-8722-6-26 PMID 23547895
    Consulter

  • Monitoring Response and Resistance to the Novel Arsenical Darinaparsin in an AML Patient

    Torsten H Nielsen, Nathalie Johnson, Nicolas Garnier, Stanley Kwan, Lu Yao, Eftihia Cocolakis , Josée Hébert , Robert A Morgan, Eric Paquet, Kevin P Callahan, Craig T Jordan, Sarit Assouline, Wilson H Miller Jr, Koren K Mann
    DOI 10.3389/fphar.2013.00009 PMID 23408639
    Consulter

  • A role for GPx3 in activity of normal and leukemia stem cells

    Olivier Herault, Kristin J Hope, Eric Deneault, Nadine Mayotte, Jalila Chagraoui, Brian T Wilhelm, Sonia Cellot, Martin Sauvageau, Miguel A Andrade-Navarro , Josée Hébert , Guy Sauvageau
    DOI 10.1084/jem.20102386 PMID 22508837
    Consulter

  • A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia

    Camille Simon, Jalila Chagraoui, Jana Krosl, Patrick Gendron, Brian Wilhelm, Sébastien Lemieux, Geneviève Boucher, Pierre Chagnon, Simon Drouin, Raphaëlle Lambert, Claude Rondeau , Annie Bilodeau, Sylvie Lavallée, Martin Sauvageau , Josée Hébert , Guy Sauvageau
    DOI 10.1101/gad.186411.111 PMID 22431509
    Consulter

  • The MRE11 GAR motif regulates DNA double-strand break processing and ATR activation

    Zhenbao Yu, Gillian Vogel, Yan Coulombe, Danielle Dubeau, Elizabeth Spehalski , Josée Hébert , David O Ferguson, Jean Yves Masson, Stéphane Richard
    DOI 10.1038/cr.2011.128 PMID 21826105
    Consulter

  • Sef downregulation by Ras causes MEK1/2 to become aberrantly nuclear localized leading to polyploidy and neoplastic transformation

    Stéphanie Duhamel , Josée Hébert , Louis Gaboury, Amélie Bouchard, Ronald Simon, Guido Sauter, Mark Basik, Sylvain Meloche
    DOI 10.1158/0008-5472.CAN-11-2126 PMID 22298595
    Consulter

  • Chromosome arm-specific long telomeres: a new clonal event in primary chronic myelogenous leukemia cells

    Oumar Samassekou, Huiyu Li , Josée Hébert , Aimé Ntwari, Haixia Wang, Catherine Grenier Cliché, Eric Bouchard, Shiang Huang, Ju Yan
    DOI 10.1593/neo.11358 PMID 21677878
    Consulter

  • Modeling T-cell acute lymphoblastic leukemia induced by the SCL and LMO1 oncogenes

    Mathieu Tremblay, Cédric S Tremblay, Sabine Herblot, Peter D Aplan , Josée Hébert , Claude Perreault, Trang Hoang
    DOI 10.1101/gad.1897910 PMID 20516195
    Consulter

  • Microhomologies and topoisomerase II consensus sequences identified near the breakpoint junctions of the recurrent t(7;21)(p22;q22) translocation in acute myeloid leukemia

    Amélie Giguère , Josée Hébert
    DOI 10.1002/gcc.20848 PMID 21319259
    Consulter

  • An anticlastogenic function for the Polycomb Group gene Bmi1

    Jalila Chagraoui , Josée Hébert , Simon Girard , Guy Sauvageau
    DOI 10.1073/pnas.1014263108 PMID 21402923
    Consulter

  • Growth factor independence 1 protects hematopoietic stem cells against apoptosis but also prevents the development of a myeloproliferative-like disease

    Cyrus Khandanpour, Christian Kosan, Marie-Claude Gaudreau, Ulrich Dührsen , Josée Hébert , Hui Zeng, Tarik Möröy
    DOI 10.1002/stem.575 PMID 21732494
    Consulter

  • RNA-seq analysis of 2 closely related leukemia clones that differ in their self-renewal capacity

    Brian T. Wilhelm, Mathieu Briau, Pamela Austin, Amélie Faubert, Geneviève Boucher, Pierre Chagnon, Kristin Hope, Simon Girard, Nadine Mayotte, Josette-Renee Landry , Josée Hébert , Guy Sauvageau
    DOI 10.1182/blood-2010-07-293332 PMID 20980679
    Consulter

  • Genome-wide interrogation of Mammalian stem cell fate determinants by nested chromosome deletions

    Simon Fortier, Mélanie Bilodeau, Tara Macrae, Jean-Philippe Laverdure, Valeria Azcoitia, Simon Girard, Jalila Chagraoui, Nancy Ringuette , Josée Hébert , Jana Krosl, Nadine Mayotte , Guy Sauvageau
    DOI 10.1371/journal.pgen.1001241 PMID 21170304
    Consulter

  • Breast carcinoma-associated fibroblasts rarely contain p53 mutations or chromosomal aberrations

    Abdel Nasser Hosein, Min Wu, Suzanna L Arcand, Sylvie Lavallée , Josée Hébert , Patricia N Tonin, Mark Basik
    DOI 10.1158/0008-5472.CAN-10-0673 PMID 20570891
    Consulter

  • Individual telomere lengths in chronic myeloid leukemia

    Oumar Samassekou, Aimé Ntwari , Josée Hébert , Ju Yan
    DOI 10.1593/neo.09836 PMID 19881950
    Consulter

  • A mouse PRMT1 null allele defines an essential role for arginine methylation in genome maintenance and cell proliferation

    Zhenbao Yu, Taiping Chen , Josée Hébert , En Li, Stéphane Richard
    DOI 10.1128/MCB.00042-09 PMID 19289494
    Consulter

  • Allelic methylation bias of the RARB2 tumor suppressor gene promoter in cancer

    Jane J Pappas, André Toulouse , Josée Hébert , Raouf Fetni, W E C Bradley
    DOI 10.1002/gcc.20603 PMID 18663751
    Consulter

  • Evidence suggesting the presence of a stem cell clone anteceding the acquisition of the JAK2-V617F mutation

    R Jamal, C Bélisle, M-C Lessard , Josée Hébert , Denis-Claude Roy , R Levine , Lambert Busque
    DOI 10.1038/leu.2008.6 PMID 18239619
    Consulter

  • Characterization of three new serous epithelial ovarian cancer cell lines

    Véronique Ouellet, Magdalena Zietarska, Lise Portelance, Julie Lafontaine, Jason Madore, Marie-Line Puiffe, Suzanna L Arcand, Zhen Shen , Josée Hébert , Patricia N Tonin, Diane M Provencher, Anne-Marie Mes-Masson
    DOI 10.1186/1471-2407-8-152 PMID 18507860
    Consulter

  • Quantitative expression profiling guided by common retroviral insertion sites reveals novel and cell type specific cancer genes in leukemia

    Martin Sauvageau, Michelle Miller, Sébastien Lemieux, Julie Lessard , Josée Hébert , Guy Sauvageau
    DOI 10.1182/blood-2007-07-098236 PMID 17906077
    Consulter

  • Rapid and selective death of leukemia stem and progenitor cells induced by the compound 4-benzyl, 2-methyl, 1,2,4-thiadiazolidine, 3,5 dione (TDZD-8)

    Monica L Guzman, Xiaojie Li, Cheryl A Corbett, Randall M Rossi, Timothy Bushnell, Jane L Liesveld, , Josée Hébert , Fay Young, Craig T Jordan
    DOI 10.1182/blood-2007-05-088815 PMID 17785584
    Consulter

  • Galectin-7 in lymphoma: elevated expression in human lymphoid malignancies and decreased lymphoma dissemination by antisense strategies in experimental model

    Mélanie Demers, Katherine Biron-Pain , Josée Hébert , Alain Lamarre, Thierry Magnaldo, Yves St-Pierre
    DOI 10.1158/0008-5472.CAN-06-3891 PMID 17363605
    Consulter

  • A retroviral strategy that efficiently creates chromosomal deletions in mammalian cells

    Mélanie Bilodeau, Simon Girard , Josée Hébert , Guy Sauvageau
    DOI 10.1038/nmeth1011 PMID 17277782
    Consulter

  • The réseau de recherche sur le cancer: favoring a multi-disciplinary approach

    Anne-Marie Mes-Masson, Louise Champoux , Josée Hébert , Gerald Batist, Bernard Lespérance
    PMID 16980224
    Consulter

  • Allogeneic transplantation for multiple myeloma: further evidence for a GVHD-associated graft-versus-myeloma effect

    Richard LeBlanc , S Montminy-Métivier, R Bélanger , Lambert Busque , D Fish , Denis-Claude Roy , Jeannine Kassis , J Boileau, R Lavallée, D Bélanger, F Letendre , Josée Hébert , Guy Sauvageau , C Perreault , Jean Roy
    DOI 10.1038/sj.bmt.1703253 PMID 11781644
    Consulter

  • Homozygous MTS1 (p16INK4A) deletion in primary tumor cells of 163 leukemic patients

    J M Cayuela , Josée Hébert , F Sigaux
    PMID 7833489
    Consulter

  • Inversion-associated translocations in acute myelomonocytic leukemia with eosinophilia

    R Berger, J Derré, M Le Coniat , Josée Hébert , P S Romana, P Jonveaux
    DOI 10.1002/gcc.2870120110 PMID 7534112
    Consulter

  • Candidate tumor-suppressor genes MTS1 (p16INK4A) and MTS2 (p15INK4B) display frequent homozygous deletions in primary cells from T- but not from B-cell lineage acute lymphoblastic leukemias

    Josée Hébert , J M Cayuela, J Berkeley, F Sigaux
    PMID 7994022
    Consulter

  • Detection of minimal residual disease in acute myelomonocytic leukemia with abnormal marrow eosinophils by nested polymerase chain reaction with allele specific amplification

    Josée Hébert , J M Cayuela, M T Daniel, R Berger, F Sigaux
    PMID 7919348
    Consulter

  • Cytogenetic studies in patients with Richter's syndrome

    Josée Hébert , P Jonveaux, M F d'Agay, R Berger
    DOI 10.1016/0165-4608(94)90184-8 PMID 8174077
    Consulter

  • Translocation t(3;22)(q27;q11) in non-Hodgkin's malignant lymphoma: chromosome painting and molecular studies

    Josée Hébert , S P Romana, J Hillion, J P Kerkaert, C Bastard, R Berger
    PMID 8255095
    Consulter

  • Increase in T3 levels during hypocorticism in patients with chronic secondary adrenocortical insufficiency

    R Comtois , Josée Hébert , J P Soucy
    DOI 10.1530/acta.0.1260319 PMID 1317631
    Consulter

  • Reversible hypertriiodothyroninaemia due to adrenal insufficiency

    R Comtois , Josée Hébert , J P Soucy
    DOI 10.1111/j.1365-2796.1991.tb00409.x PMID 2066714
    Consulter