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Centre intégré universitaire de santé
et de services sociaux de l'Est-de-l'Île-de-Montréal

Centre intégré universitaire de santé et de services sociaux de l'Est-de-l'Île-de-Montréal

Natasha Szuber, M.D., M. Sc.

Natasha Szuber

Hémato-oncologue, Professeure agrégée de clinique

L'équipe de l’IHOT

Médecin

Contact

Tél. : 514 252-3404

En plus de sa formation médicale, Dre Natasha Szuber a obtenu une maîtrise en physiologie de l’Université McGill. Ses intérêts en clinique et en recherche sont principalement axés sur les néoplasies myéloprolifératives et les maladies « imitatrices » tels les érythrocytoses secondaires. 

 

  • Clinicienne chercheure FRQS
  • Entrée en poste à l’Hôpital Maisonneuve-Rosemont : 2018

 

Formation :

  • Fellowship en hématologie : Mayo Clinic, Rochester (États-Unis), 2017-2018
  • Résidences en médecine interne, hématologie et oncologie médicale : Université de Montréal (Canada), 2010-2016
  • Doctorat en médecine : Université de Montréal (Canada), 2005-2010
  • Maîtrise en physiologie : Université McGill, Montréal (Canada), 2002-2005

Découvrez ses publications

  • Proposals for Revised International Working Group-European LeukemiaNet Criteria for Anemia Response in Myelofibrosis

    Ayalew Tefferi, Giovanni Barosi, Francesco Passamonti, Juan Carlos Hernandez-Boluda, Prithviraj Bose, Konstanze Döhner, Martin Ellis, Naseema Gangat, Jacqueline S. Garcia, Heinz Gisslinger, Jason Gotlib, Paola Guglielmelli, Vikas Gupta, Claire N. Harrison , Elizabeth O. Hexner, Gabriela S Hobbs, Jean-Jacques Kiladjian, Steffen Koschmieder, Nicolaus Kröger, Andrew T Kuykendall, Giuseppe Gaetano Loscocco , John O. Mascarenhas, Lucia Masarova, Ruben Mesa, Barbara Mora, Olatoyosi Odenike, Stephen T. Oh, Animesh D Pardanani, Anand A Patel, Naveen Pemmaraju, Alessandro Rambaldi, Raajit K. Rampal, Shireen Sirhan , Natasha Szuber , Moshe Talpaz, Pankit Vachhani, Alessandro M. Vannucchi, Tiziano Barbui
    DOI 10.1182/blood.2024025802 PMID 39116296
    Consulter

  • Methodological challenges in the development of endpoints for myelofibrosis clinical trials

    Giovanni Barosi, Ayalew Tefferi, Naseema Gangat , Natasha Szuber , Alessandro Rambaldi, Olatoyosi Odenike, Nicolaus Kröger, Nico Gagelmann, Moshe Talpaz, Hagop Kantarjian, Robert Peter Gale
    DOI 10.1016/S2352-3026(24)00067-X PMID 38604205
    Consulter

  • Chronic neutrophilic leukemia and atypical chronic myeloid leukemia: 2024 update on diagnosis, genetics, risk stratification, and management

    Natasha Szuber , Attilio Orazi, Ayalew Tefferi
    DOI 10.1002/ajh.27321 PMID 38644693
    Consulter

  • CALR mutation burden in essential thrombocythemia and disease outcome

    Paola Guglielmelli , Natasha Szuber , Naseema Gangat, Giulio Capecchi, Chiara Maccari, Michaël Harnois, Omer Karrar, Maymona Abdelmagid, Manjola Balliu, Elena Nacca, Alessandro Atanasio, Ilaria Sestini, Audrey Désilets, Giuseppe Gaetano Loscocco, Giada Rotunno , Lambert Busque , Ayalew Tefferi, Alessandro Maria Vannucchi
    DOI 10.1182/blood.2023023428 PMID 38252902
    Consulter

  • Clinical Features and Long-Term Outcomes of a Pan-Canadian Cohort of Adolescents and Young Adults with Myeloproliferative Neoplasms: A Canadian MPN Group Study

    James T. England , Natasha Szuber , Shireen Sirhan, Tom Dunne, Sonia Cerquozzi, Madeleine Hill, Pierre J. A. Villeneuve, Jenny M. Ho, Bekim Sadikovic, Pratibha Bhai, Nupur Krishnan, Sebastian Dowhanik, Chris Hillis, Jose-Mario Capo-Chichi, Hubert Tsui, Verna Cheung, Karine Gauthier , Hassan Sibai, Marta B. Davidson, Aniket Bankar, Rouslan Kotchetkov, Vikas Gupta, Dawn Maze
    DOI 10.1038/s41375-024-02155-4 PMID 38321107
    Consulter

  • A globally applicable "triple A" risk model for essential thrombocythemia based on Age, Absolute neutrophil count, and Absolute lymphocyte count

    Ayalew Tefferi, Giuseppe G. Loscocco, Faiqa Farrukh , Natasha Szuber , Francesco Mannelli, Animesh Pardanani, Curtis A. Hanson, Rhett P. Ketterling, Valerio De Stefano, Alessandra Carobbio, Tiziano Barbui, Paola Guglielmelli, Naseema Gangat, Alessandro M. Vannucchi
    DOI 10.1002/ajh.27079 PMID 37665758
    Consulter

  • Interplay between hereditary and acquired factors determines the neutrophil counts in older individuals

    Marie-France Gagnon , Sylvie Provost, Maxine Sun, Sami Ayachi, Manuel Buscarlet , Luigina Mollica , Natasha Szuber , Marie-Pierre Dubé , Lambert Busque
    DOI 10.1182/bloodadvances.2022008793 PMID 36930802
    Consulter

  • JAK2 unmutated erythrocytosis: 2023 Update on diagnosis and management

    Naseema Gangat , Natasha Szuber , Ayalew Tefferi
    DOI 10.1002/ajh.26920 PMID 36966432
    Consulter

  • Sodium-glucose co-transporter-2 inhibitor use and JAK2 unmutated erythrocytosis in 100 consecutive cases

    Naseema Gangat, Mostafa Abdallah , Natasha Szuber , Antoine Saliba, Hassan Alkhateeb, Aref Al-Kali, Kebede H. Begna, Animesh Pardanani, Ayalew Tefferi
    DOI 10.1002/ajh.26933 PMID 37073574
    Consulter

  • Higher Rates of Perioperative Thrombosis and Distinct Management Practices in Secondary Erythrocytosis Versus Polycythemia Vera

    Natasha Szuber , Michael Harnois, Robert Delage, Shireen Sirhan , Lambert Busque
    DOI 10.1182/blood-2022-170026
    Consulter

  • Prognostic Impact of High Calreticulin Variant Allele Frequency in Patients with Myeloproliferative Neoplasms

    Audrey Desilets, Michael Harnois , Lambert Busque , Natasha Szuber
    DOI 10.1182/blood-2022-163785
    Consulter

  • Site-specific venous thrombosis in essential thrombocythemia: Impact on subsequent vascular events and survival

    Naseema Gangat, Amritpal Singh , Natasha Szuber , Kebede Begna, Michelle Elliott, Alexandra Wolanskyj-Spinner, Curtis A Hanson, Animesh Pardanani, Valerio De Stefano, Tiziano Barbui, Alessandro M Vannucchi, Ayalew Tefferi
    DOI 10.1111/jth.15834 PMID 35894106
    Consulter

  • Perioperative management of myeloproliferative neoplasms: A pan-Canadian physician survey and international expert opinion

    Natasha Szuber , Panagiota Toliopoulos , Lambert Busque , Sonia Cerquozzi, Lynda Foltz, Vikas Gupta, Ayalew Tefferi, Alessandro Maria Vannucchi, Christopher Hillis, Brian Leber, Dawn Maze, Jaroslav Prchal, Harold J. Olney, Shireen Sirhan
    DOI 10.1002/ajh.26739 PMID 36151067
    Consulter

  • 1.5 million platelet count limit at essential thrombocythemia diagnosis: correlations and relevance to vascular events

    Naseema Gangat , Natasha Szuber , Yamna Jadoon, Faiqa Farrukh, Kebede Begna, Michelle A. Elliott, Alexandra P. Wolanskyj-Spinner, Curtis A. Hanson, Animesh D. Pardanani, Valerio De Stefano, Tiziano Barbui, Alessandro Maria Vannucchi, Ayalew Tefferi
    DOI 10.1182/bloodadvances.2022007023 PMID 35271689
    Consulter

  • Myeloproliferative neoplasms - a global view

    Ayalew Tefferi, Jean-Christophe Ianotto, Vikram Mathews, Jan Samuelsson , Natasha Szuber , Zhijian Xiao, Peter Hokland
    DOI 10.1111/bjh.18213 PMID 35482584
    Consulter

  • Cytogenetic abnormalities in essential thrombocythemia: Clinical and molecular correlates and prognostic relevance in 809 informative cases

    Naseema Gangat, Yamna Jadoon , Natasha Szuber , Curtis A Hanson, Alexandra P Wolanskyj-Spinner, Rhett P Ketterling, Animesh Pardanani, Ayalew Tefferi
    DOI 10.1038/s41408-022-00639-z PMID 35301278
    Consulter

  • Chronic neutrophilic leukemia: 2022 update on diagnosis, genomic landscape, prognosis, and management

    Natasha Szuber , Michelle Elliott, Ayalew Tefferi
    DOI 10.1002/ajh.26481 PMID 35089603
    Consulter

  • JAK2 wild-type erythrocytosis associated with sodium-glucose cotransporter 2 inhibitor therapy

    Naseema Gangat , Natasha Szuber , Hassan Alkhateeb, Aref Al-Kali, Animesh Pardanani, Ayalew Tefferi
    DOI 10.1182/blood.2021013996 PMID 34653249
    Consulter

  • A population-based study of outcomes in polycythemia vera, essential thrombocythemia, and primary myelofibrosis in the United States from 2001 to 2015: Comparison with data from a Mayo Clinic single institutional series

    Caleb J Smith, John W Thomas, Gordon Ruan, Meredith C Hyun, Radhika Bansal, Nicole McLaughlin, Animesh Pardanani, Naseema Gangat, Ronald S Go , Natasha Szuber , Gaurav Goyal, Mithun Vinod Shah, Ayalew Tefferi
    DOI 10.1002/ajh.26377 PMID 34661932
    Consulter

  • JAK2 unmutated erythrocytosis: current diagnostic approach and therapeutic views

    Naseema Gangat , Natasha Szuber , Animesh Pardanani, Ayalew Tefferi
    DOI 10.1038/s41375-021-01290-6 PMID 34021251
    Consulter

  • Venetoclax with azacitidine or decitabine in blast-phase myeloproliferative neoplasm: A multicenter series of 32 consecutive cases

    Naseema Gangat, Paola Guglielmelli , Natasha Szuber , Kebede H Begna, Mrinal M Patnaik, Mark R Litzow, Aref Al-Kali, James M Foran, Jeanne M Palmer, Hassan Alkhateeb, Michelle A Elliott, Curtis A , Animesh Pardanani, Francesco Mannelli, Alessandro M Vannucchi, Ayalew Tefferi
    DOI 10.1002/ajh.26186 PMID 33844862
    Consulter

  • Current Management of Chronic Neutrophilic Leukemia

    Natasha Szuber , Ayalew Tefferi
    DOI 10.1007/s11864-021-00856-x PMID 34097138
    Consulter

  • Extreme thrombocytosis in low-risk essential thrombocythemia: Retrospective review of vascular events and treatment strategies

    Ayalew Tefferi , Natasha Szuber , Animesh Pardanani, Curtis A Hanson, Alessandro M Vannucchi, Tiziano Barbui, Naseema Gangat
    DOI 10.1002/ajh.26137 PMID 33617676
    Consulter

  • Risk of infection in MPN patients in the era of Covid-19: A prospective multicenter study of 257 patients from the CML-MPN Quebec Research Group

    Kevin Simpson-Poirier, Michaël Harnois, Harold J Olney, Shireen Sirhan , Michel-Olivier Gratton , Sarit Assouline, Pierre Laneuville, Robert Delage , Luigina Mollica , Lambert Busque , Natasha Szuber
    DOI 10.1002/ajh.26159 PMID 33719144
    Consulter

  • Mutations and thrombosis in essential thrombocythemia

    Paola Guglielmelli, Naseema Gangat, Giacomo Coltro, Terra L Lasho, Giuseppe Gaetano Loscocco, Christy M Finke, Erika Morsia, Benedetta Sordi , Natasha Szuber , Curtis A Hanson, Animesh Pardanani, Alessandro M Vannucchi, Ayalew Tefferi
    DOI 10.1038/s41408-021-00470-y PMID 33907189
    Consulter

  • Phenotypical differences and thrombosis rates in secondary erythrocytosis versus polycythemia vera

    Eliane Nguyen, Michaël Harnois , Lambert Busque , Shireen Sirhan, Sarit Assouline, Ines Chamaki, Harold Olney , Luigina Mollica , Natasha Szuber
    DOI 10.1038/s41408-021-00463-x PMID 33859172
    Consulter

  • Young platelet millionaires with essential thrombocythemia

    Naseema Gangat , Natasha Szuber , Tabinda Jawaid, Curtis A Hanson, Animesh Pardanani, Ayalew Tefferi
    DOI 10.1002/ajh.26114 PMID 33524176
    Consulter

  • A population-based study of chronic neutrophilic leukemia in the United States

    Gordon J. Ruan, Caleb J. Smith, Courtney Day, William S. Harmsen, Darci L. Zblewski, Hassan Alkhateeb, Kebede Begna, Aref Al-Kali, Mark R. Litzow, William Hogan , Natasha Szuber , Naseema Gangat, Mrinal S. Patnaik, Animesh Pardanani, Michelle A. Elliott, Ayalew Tefferi, Ronald S. Go, Mithun V. Shah
    DOI 10.1038/s41408-020-0334-1 PMID 32541648
    Consulter

  • Mutation-enhanced international prognostic systems for essential thrombocythaemia and polycythaemia vera

    Ayalew Tefferi, Paola Guglielmelli, Terra L Lasho, Giacomo Coltro, Christy M Finke, Giuseppe G Loscocco, Benedetta Sordi , Natasha Szuber , Giada Rotunno, Annalisa Pacilli, Curtis A Hanson, Rhett P Ketterling, Animesh Pardanani, Naseema Gangat, Alessandro M Vannucchi
    DOI 10.1111/bjh.16380 PMID 31945802
    Consulter

  • Chronic neutrophilic leukemia: 2020 update on diagnosis, molecular genetics, prognosis, and management

    Natasha Szuber , Michelle Elliott, Ayalew Tefferi
    DOI 10.1002/ajh.25688 PMID 31769070
    Consulter

  • 3023 Mayo Clinic Patients With Myeloproliferative Neoplasms: Risk-Stratified Comparison of Survival and Outcomes Data Among Disease Subgroups

    Natasha Szuber , Mythri Mudireddy, Maura Nicolosi, Domenico Penna, Rangit R Vallapureddy, Terra L Lasho, Christy Finke, Kebede H Begna, Michelle A Elliott, C Christopher Hook, Alexandra P Wolanskyj, Mrinal M Patnaik, Curtis A Hanson , Rhett P Ketterling, Shireen Sirhan, Animesh Pardanani, Naseema Gangat , Lambert Busque , Ayalew Tefferi
    DOI 10.1016/j.mayocp.2018.08.022 PMID 30824279
    Consulter

  • Determinants of long-term outcome in type 1 calreticulin-mutated myelofibrosis

    Natasha Szuber , Terra L Lasho, Christy Finke, Curtis A Hanson, Rhett P Ketterling, Animesh Pardanani, Naseema Gangat, Ayalew Tefferi
    DOI 10.1038/s41375-018-0283-x PMID 30315236
    Consulter

  • Decreased survival and increased rate of fibrotic progression in essential thrombocythemia chronicled after the FDA approval date of anagrelide

    Ayalew Tefferi , Natasha Szuber , Rangit R Vallapureddy, Kebede H Begna, Mrinal M Patnaik, Michelle A Elliott, C Christopher Hook, Alexandra P Wolanskyj, Curtis A Hanson, Rhett P Ketterling, Animesh Pardanani, Naseema Gangat
    DOI 10.1002/ajh.25294 PMID 30252953
    Consulter

  • Myeloproliferative neoplasms in the young: Mayo Clinic experience with 361 patients age 40 years or younger

    Natasha Szuber , Rangit R Vallapureddy, Domenico Penna, Terra L Lasho, Christy Finke, Curtis A Hanson, Rhett P Ketterling, Animesh Pardanani, Naseema Gangat, Ayalew Tefferi
    DOI 10.1002/ajh.25270 PMID 30157297
    Consulter

  • MPL-mutated essential thrombocythemia: a morphologic reappraisal

    Natasha Szuber , Curtis A Hanson, Terra L Lasho, Christy Finke, Rhett P Ketterling, Animesh Pardanani, Naseema Gangat, Ayalew Tefferi
    DOI 10.1038/s41408-018-0159-3 PMID 30459342
    Consulter

  • Serum erythropoietin levels in essential thrombocythemia: phenotypic and prognostic correlates

    Natasha Szuber , Sravanthi Lavu, Mythri Mudireddy, Maura Nicolosi, Domenico Penna, Rangit R Vallapureddy, Terra L Lasho, Christy Finke, Curtis A Hanson, Rhett P Ketterling, Animesh Pardanani, Naseema Gangat, Ayalew Tefferi
    DOI 10.1038/s41408-018-0157-5 PMID 30455425
    Consulter

  • Genetic predictors of response to specific drugs in primary myelofibrosis

    Domenico Penna , Natasha Szuber , Terra L Lasho, Christy M Finke, Rangit R Vallapureddy, Curtis A Hanson, Rhett P Ketterling, Animesh Pardanani, Naseema Gangat, Ayalew Tefferi
    DOI 10.1038/s41408-018-0158-4 PMID 30455475
    Consulter

  • Development of a prognostically relevant cachexia index in primary myelofibrosis using serum albumin and cholesterol levels

    Ayalew Tefferi, Maura Nicolosi, Domenico Penna, Mythri Mudireddy , Natasha Szuber , Terra L. Lasho, Curtis A. Hanson, Rhett P. Ketterling, Naseema Gangat, Animesh D. Pardanani
    DOI 10.1182/bloodadvances.2018018051 PMID 30097464
    Consulter

  • The impact of sex on disease phenotype and prognostic thresholds of anemia in myelodysplastic syndromes

    Domenico Penna, Maura Nicolosi, Rangit R Vallapureddy , Natasha Szuber , Terra L Lasho, Curtis A Hanson, Rhett P Ketterling, Animesh Pardanani, Naseema Gangat, Ayalew Tefferi
    DOI 10.1002/ajh.25114 PMID 29659079
    Consulter

  • Driver mutations in primary myelofibrosis and their implications

    Natasha Szuber , Ayalew Tefferi
    DOI 10.1097/MOH.0000000000000406 PMID 29256926
    Consulter

  • Driver mutations and prognosis in primary myelofibrosis: Mayo-Careggi MPN alliance study of 1,095 patients

    Ayalew Tefferi, Maura Nicolosi, Mythri Mudireddy , Natasha Szuber , Christy M Finke, Terra L Lasho, Curtis A Hanson, Rhett P Ketterling, Animesh Pardanani, Naseema Gangat , Carmela Mannarelli, Tiziana Fanelli, Paola Guglielmelli, Alessandro M Vannucchi
    DOI 10.1002/ajh.24978 PMID 29164670
    Consulter

  • Mutations and prognosis in myelodysplastic syndromes: karyotype-adjusted analysis of targeted sequencing in 300 consecutive cases and development of a genetic risk model

    Naseema Gangat, Mythri Mudireddy, Terra L Lasho, Christy M Finke, Maura Nicolosi , Natasha Szuber , Mrinal M Patnaik, Animesh Pardanani, Curtis A Hanson, Rhett P Ketterling, Ayalew Tefferi
    DOI 10.1002/ajh.25064 PMID 29417633
    Consulter

  • Splanchnic vein thrombosis in patients with myeloproliferative neoplasms: The Mayo clinic experience with 84 consecutive cases

    Sravanthi Lavu , Natasha Szuber , Mythri Mudireddy, Meera Yogarajah, Naseema Gangat, Animesh Pardanani, Curtis A Hanson, Rhett P Ketterling, Aneel A Ashrani, Patrick S Kamath, Ayalew Tefferi
    DOI 10.1002/ajh.24993 PMID 29194707
    Consulter

  • Targeted next-generation sequencing in blast phase myeloproliferative neoplasms

    Terra L. Lasho, Mythri Mudireddy, Christy M. Finke, Curtis A. Hanson, Rhett P. Ketterling , Natasha Szuber , Kebede H. Begna, Mrinal M. Patnaik, Naseema Gangat, Animesh Pardanani, Ayalew Tefferi
    DOI 10.1182/bloodadvances.2018015875 PMID 29467191
    Consulter

  • CSF3R-mutated chronic neutrophilic leukemia: long-term outcome in 19 consecutive patients and risk model for survival

    Natasha Szuber , Christy M Finke, Terra L Lasho, Michelle A Elliott, Curtis A Hanson, Animesh Pardanani, Ayalew Tefferi
    DOI 10.1038/s41408-018-0058-7 PMID 29449543
    Consulter

  • Chronic neutrophilic leukemia: new science and new diagnostic criteria

    Natasha Szuber , Ayalew Tefferi
    DOI 10.1038/s41408-018-0049-8 PMID 29440636
    Consulter

  • DNMT3A and TET2 dominate clonal hematopoiesis and demonstrate benign phenotypes and different genetic predispositions

    Manuel Buscarlet, Sylvie Provost, Yassamin Feroz Zada, Amina Barhdadi, Vincent Bourgoin, Guylaine Lépine , Luigina Mollica , Natasha Szuber , Marie-Pierre Dubé , Lambert Busque
    DOI 10.1182/blood-2017-04-777029 PMID 28655780
    Consulter

  • Severe bleeding diatheses in an elderly patient with combined type autoantibody against factor XIII A subunit; novel approach to the diagnosis and classification of anti-factor XIII antibodies

    M Kun , Natasha Szuber , É Katona, K Pénzes, A Bonnefoy, B Bécsi, F Erdődi, G E Rivard, L Muszbek
    DOI 10.1111/hae.13205 PMID 28345289
    Consulter

  • Novel germline mutations in the calreticulin gene: implications for the diagnosis of myeloproliferative neoplasms

    Natasha Szuber , Bruno Lamontagne , Lambert Busque
    DOI 10.1136/jclinpath-2016-203940 PMID 27466382
    Consulter

  • Alternative treatment paradigm for thalassemia using iron chelators

    Natasha Szuber , Joan L Buss, Shan Soe-Lin, Hady Felfly, Marie Trudel, Prem Ponka
    DOI 10.1016/j.exphem.2008.01.006 PMID 18456387
    Consulter